Skip to main content

Articles

Page 3 of 37

  1. Homozygous CDKN2A/B deletion has been associated with an increased risk of recurrence in meningiomas. However, the evidence is confined to a limited number of studies, and the importance of heterozygous CDKN2A...

    Authors: Johannes Wach, Alim Emre Basaran, Felix Arlt, Martin Vychopen, Clemens Seidel, Alonso Barrantes-Freer, Wolf Müller, Frank Gaunitz and Erdem Güresir
    Citation: Acta Neuropathologica Communications 2023 11:189
  2. Intracranial germ cell tumors (IGCTs) are a rare subtype of central nervous system neoplasms that predominantly affect young individuals and exhibit a higher incidence in East Asia. IGCTs can be pathologically...

    Authors: Yi Zhang, Chengyi Zhong, Xindi Ke, Jifang Liu, Zhang Ye, Lin Lu, Kan Deng, Huijuan Zhu and Yong Yao
    Citation: Acta Neuropathologica Communications 2023 11:188
  3. A relevant number of cancer patients who receive potentially neurotoxic cytostatic agents develop a chemotherapy-induced peripheral neuropathy over time. Moreover, the increasing use of immunotherapies and tar...

    Authors: Stefanie Hartinger, Jakob Hammersen, Niklas A. Leistner, Anna Lawson McLean, Clemens Risse, Christian Senft, Stefanie Schütze, Bianka Heiling, Matthias Schwab and Irina Mäurer
    Citation: Acta Neuropathologica Communications 2023 11:187
  4. In IDH-mutant astrocytoma, IDH2 mutation is quite rare and biological mechanisms underlying tumor progression in IDH2-mutant astrocytoma remain elusive. Here, we report a unique case of IDH2 mutant astrocytoma, C...

    Authors: Kensuke Tateishi, Yohei Miyake, Taishi Nakamura, Hiromichi Iwashita, Takahiro Hayashi, Akito Oshima, Hirokuni Honma, Hiroaki Hayashi, Kyoka Sugino, Miyui Kato, Kaishi Satomi, Satoshi Fujii, Takashi Komori, Tetsuya Yamamoto, Daniel P. Cahill and Hiroaki Wakimoto
    Citation: Acta Neuropathologica Communications 2023 11:186
  5. Misfolded α-synuclein (α-syn) is believed to contribute to neurodegeneration in Lewy body disease (LBD) based on considerable evidence including a gene-dosage effect observed in relation to point mutations and...

    Authors: Tomoya Kon, Shelley L. Forrest, Seojin Lee, Ivan Martinez‑Valbuena, Jun Li, Nasna Nassir, Mohammed J. Uddin, Anthony E. Lang and Gabor G. Kovacs
    Citation: Acta Neuropathologica Communications 2023 11:185
  6. Pathogenic germline variants in the DNA polymerase genes POLE and POLD1 cause polymerase proofreading-associated polyposis, a dominantly inherited disorder with increased risk of colorectal carcinomas and other t...

    Authors: Christine A. M. Weber, Nicole Krönke, Valery Volk, Bernd Auber, Alisa Förster, Detlef Trost, Robert Geffers, Majid Esmaeilzadeh, Michael Lalk, Arya Nabavi, Amir Samii, Joachim K. Krauss, Friedrich Feuerhake, Christian Hartmann, Bettina Wiese, Frank Brand…
    Citation: Acta Neuropathologica Communications 2023 11:184
  7. Chemotherapy resistance is considered one of the main causes of tumor relapse, still challenging researchers for the identification of the molecular mechanisms sustaining its emergence. Here, we setup and char...

    Authors: Elena Mariotto, Elena Rampazzo, Roberta Bortolozzi, Fatlum Rruga, Ilaria Zeni, Lorenzo Manfreda, Chiara Marchioro, Martina Canton, Alice Cani, Ruben Magni, Alessandra Luchini, Silvia Bresolin, Giampietro Viola and Luca Persano
    Citation: Acta Neuropathologica Communications 2023 11:183
  8. Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are related neurodegenerative diseases that belong to a common disease spectrum based on overlapping clinical, pathological and genetic evi...

    Authors: Mari Carmen Pelaez, Antoine Desmeules, Pauline A. Gelon, Bastien Glasson, Laetitia Marcadet, Alicia Rodgers, Daniel Phaneuf, Silvia Pozzi, Paul A. Dutchak, Jean-Pierre Julien and Chantelle F. Sephton
    Citation: Acta Neuropathologica Communications 2023 11:182
  9. Tau seed amplification assays (SAAs) directly measure the seeding activity of tau and would therefore be ideal biomarkers for clinical trials targeting seeding-competent tau in Alzheimer’s disease (AD). Howeve...

    Authors: Bryan Frey, David Holzinger, Keenan Taylor, Dagmar E. Ehrnhoefer, Andreas Striebinger, Sandra Biesinger, Laura Gasparini, Michael J. O’Neill, Florian Wegner, Stefan Barghorn, Günter U. Höglinger and Roland G. Heym
    Citation: Acta Neuropathologica Communications 2023 11:181
  10. Despite the presence of significant cortical pTDP-43 inclusions of heterogeneous morphologies in patients diagnosed with amyotrophic lateral sclerosis (ALS), pathological subclassification is routinely perform...

    Authors: Rachel H. Tan, Heather McCann, Claire E. Shepherd, Monica Pinkerton, Srestha Mazumder, Emma M. Devenney, Gabrielle L. Adler, Dominic B. Rowe, Jillian Kril, Glenda M. Halliday and Matthew C. Kiernan
    Citation: Acta Neuropathologica Communications 2023 11:180
  11. Focal cortical dysplasia type II (FCDII) is the most common cause of drug-resistant focal epilepsy in children. Herein, we performed a deep histopathology-based genotype–phenotype analysis to further elucidate...

    Authors: Jonas Honke, Lucas Hoffmann, Roland Coras, Katja Kobow, Costin Leu, Tom Pieper, Till Hartlieb, Christian G. Bien, Friedrich Woermann, Thomas Cloppenborg, Thilo Kalbhenn, Ahmed Gaballa, Hajo Hamer, Sebastian Brandner, Karl Rössler, Arnd Dörfler…
    Citation: Acta Neuropathologica Communications 2023 11:179
  12. The development of novel treatments for Progressive Supranuclear Palsy (PSP) is hindered by a knowledge gap of the impact of neurodegenerative neuropathology on brain structure and function. The current standa...

    Authors: Tanrada Pansuwan, Annelies Quaegebeur, Sanne S. Kaalund, Eric Hidari, Mayen Briggs, James B. Rowe and Timothy Rittman
    Citation: Acta Neuropathologica Communications 2023 11:178
  13. Epithelial membrane protein 3 (EMP3) is an N-glycosylated tetraspanin with a putative trafficking function. It is highly expressed in isocitrate dehydrogenase-wild-type glioblastoma (IDH-wt GBM), and its high exp...

    Authors: Antoni Andreu Martija, Alexandra Krauß, Natalie Bächle, Laura Doth, Arne Christians, Damir Krunic, Martin Schneider, Dominic Helm, Rainer Will, Christian Hartmann, Christel Herold-Mende, Andreas von Deimling and Stefan Pusch
    Citation: Acta Neuropathologica Communications 2023 11:177
  14. As the progression of low-grade diffuse astrocytomas into grade 4 tumors significantly impacts patient prognosis, a better understanding of this process is of paramount importance for improved patient care. In...

    Authors: Kirsi J. Rautajoki, Serafiina Jaatinen, Anja Hartewig, Aliisa M. Tiihonen, Matti Annala, Iida Salonen, Masi Valkonen, Vili Simola, Elisa M. Vuorinen, Anni Kivinen, Minna J. Rauhala, Riikka Nurminen, Kendra K. Maass, Sirpa-Liisa Lahtela, Arja Jukkola, Olli Yli-Harja…
    Citation: Acta Neuropathologica Communications 2023 11:176
  15. MGMT promoter methylation testing is required for prognosis and predicting temozolomide response in gliomas. Accurate results depend on sufficient tumor cellularity, but histologic estimates of cellularity are su...

    Authors: Matthew McCord, Pouya Jamshidi, Vineeth Thirunavu, Lucas Santana-Santos, Erica Vormittag-Nocito, David Dittman, Stephanie Parker, Joseph Baczkowski, Lawrence Jennings, Jordain Walshon, Kathleen McCortney, Kristyn Galbraith, Hui Zhang, Rimas V. Lukas, Roger Stupp, Karan Dixit…
    Citation: Acta Neuropathologica Communications 2023 11:175
  16. Group 3 medulloblastoma is one of the most aggressive types of childhood brain tumors. Roughly 30% of cases carry genetic alterations in MYC, SMARCA4, or both genes combined. While overexpression of MYC has previ...

    Authors: Carolin Göbel, Shweta Godbole, Melanie Schoof, Dörthe Holdhof, Catena Kresbach, Carolin Loose, Julia Neumann and Ulrich Schüller
    Citation: Acta Neuropathologica Communications 2023 11:174
  17. Authors: Louise Reveret, Manon Leclerc, Vincent Emond, Cyntia Tremblay, Andréanne Loiselle, Philippe Bourassa, David A. Bennett, Sébastien S. Hébert and Frédéric Calon
    Citation: Acta Neuropathologica Communications 2023 11:173

    The original article was published in Acta Neuropathologica Communications 2023 11:159

  18. Distinctive post-translational modifications (PTM) characterize tau inclusions found in tauopathy patients. Using detergent-insoluble tau isolated from Alzheimer’s disease (AD-tau) or Progressive Supranuclear ...

    Authors: Ethan D. Smith, Quan Vo, Benoit I. Giasson, David R. Borchelt, Stefan Prokop and Paramita Chakrabarty
    Citation: Acta Neuropathologica Communications 2023 11:172
  19. Glaucoma, the second leading cause of irreversible blindness worldwide, is associated with age and sensitivity to intraocular pressure (IOP). We have shown that elevated IOP causes an early increase in levels ...

    Authors: Sarah Naguib, Jon R. Backstrom, Elisabeth Artis, Purnima Ghose, Amy Stahl, Rachael Hardin, Ameer A. Haider, John Ang, David J. Calkins and Tonia S. Rex
    Citation: Acta Neuropathologica Communications 2023 11:171
  20. Authors: Arnault Tauziède-Espariat, Emmanuelle Uro-Coste, Yvan Nicaise, Philipp Sievers, Andreas von Deimling, Felix Sahm, Oumaima Aboubakr, Alice Métais, Fabrice Chrétien and Pascale Varlet
    Citation: Acta Neuropathologica Communications 2023 11:170
  21. Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) comprise a spectrum of neurodegenerative diseases linked to TDP-43 proteinopathy, which at the cellular level, is characterized by loss of ...

    Authors: R. Keating Godfrey, Eric Alsop, Reed T. Bjork, Brijesh S. Chauhan, Hillary C. Ruvalcaba, Jerry Antone, Lauren M. Gittings, Allison F. Michael, Christi Williams, Grace Hala’ufia, Alexander D. Blythe, Megan Hall, Rita Sattler, Kendall Van Keuren-Jensen and Daniela C. Zarnescu
    Citation: Acta Neuropathologica Communications 2023 11:168
  22. Duchenne muscular dystrophy (DMD) is a devastating X-linked muscular disease, caused by mutations in the DMD gene encoding Dystrophin and affecting 1:5000 boys worldwide. Lack of Dystrophin leads to progressive m...

    Authors: Nastasia Cardone, Valentina Taglietti, Serena Baratto, Kaouthar Kefi, Baptiste Periou, Ciryl Gitiaux, Christine Barnerias, Peggy Lafuste, France Leturcq Pharm, Juliette Nectoux Pharm, Chiara Panicucci, Isabelle Desguerre, Claudio Bruno, François-Jerome Authier, Chiara Fiorillo, Frederic Relaix…
    Citation: Acta Neuropathologica Communications 2023 11:167
  23. Tau tubulin kinase-1 (TTBK1), a neuron-specific tau kinase, is highly expressed in the entorhinal cortex and hippocampal regions, where early tau pathology evolves in Alzheimer’s disease (AD). The protein expr...

    Authors: Kayo Yukawa, Satomi Yamamoto-Mcguire, Louis Cafaro, Christine Hong, Fredrik Kamme, Tsuneya Ikezu and Seiko Ikezu
    Citation: Acta Neuropathologica Communications 2023 11:166
  24. Facioscapulohumeral muscular dystrophy (FSHD) is an autosomal dominant epigenetic disorder with highly variable muscle involvement and disease progression. Ongoing clinical trials, aimed at counteracting muscl...

    Authors: Elvira Ragozzino, Sara Bortolani, Lorena Di Pietro, Andrea Papait, Ornella Parolini, Mauro Monforte, Giorgio Tasca and Enzo Ricci
    Citation: Acta Neuropathologica Communications 2023 11:165
  25. Identifying genetic modifiers of familial amyotrophic lateral sclerosis (ALS) may reveal targets for therapeutic modulation with potential application to sporadic ALS. GGGGCC (G4C2) repeat expansions in the C9orf...

    Authors: Craig L. Bennett, Somasish Dastidar, Frederick J. Arnold, Spencer U. McKinstry, Cameron Stockford, Brian D. Freibaum, Bryce L. Sopher, Meilin Wu, Glen Seidner, William Joiner, J. Paul Taylor, Ryan J. H. West and Albert R. La Spada
    Citation: Acta Neuropathologica Communications 2023 11:164
  26. Rare cases of paraneoplastic obesity in children suggest sporadic obesity might also arise from an adaptive immune cell-mediated mechanism. Since the hypothalamus is a central regulator of feeding behavior and...

    Authors: Jared T. Ahrendsen, Yi Nong, Yuda Huo, Jasmine Steele and Matthew P. Anderson
    Citation: Acta Neuropathologica Communications 2023 11:163
  27. The alpha-synuclein (aSyn) seed amplification assay (SAA) can identify aSyn aggregates as indicator for Lewy body pathology in biomaterials of living patients and help in diagnosing Parkinson´s disease and dem...

    Authors: Stefan Bräuer, Marcello Rossi, Johann Sajapin, Thomas Henle, Thomas Gasser, Piero Parchi, Kathrin Brockmann and Björn H. Falkenburger
    Citation: Acta Neuropathologica Communications 2023 11:162
  28. Mice transgenic for human mutant P301S tau are widely used as models for human tauopathies. They develop neurodegeneration and abundant filamentous inclusions made of human mutant four-repeat tau. Here we used...

    Authors: Manuel Schweighauser, Alexey G. Murzin, Jennifer Macdonald, Isabelle Lavenir, R. Anthony Crowther, Sjors H.W. Scheres and Michel Goedert
    Citation: Acta Neuropathologica Communications 2023 11:160
  29. Cognitive decline due to Alzheimer’s disease (AD) is frequent in the geriatric population, which has been disproportionately affected by the COVID-19 pandemic. In this study, we investigated the levels of angi...

    Authors: Louise Reveret, Manon Leclerc, Vincent Emond, Cyntia Tremblay, Andréanne Loiselle, Philippe Bourassa, David A. Bennett, Sébastien S. Hébert and Frédéric Calon
    Citation: Acta Neuropathologica Communications 2023 11:159

    The Correction to this article has been published in Acta Neuropathologica Communications 2023 11:173

  30. In Parkinson’s disease, pathogenic factors such as the intraneuronal accumulation of the protein α-synuclein affect key metabolic processes. New approaches are required to understand how metabolic dysregulatio...

    Authors: Sofia Spataro, Bohumil Maco, Stéphane Escrig, Louise Jensen, Lubos Polerecky, Graham Knott, Anders Meibom and Bernard L. Schneider
    Citation: Acta Neuropathologica Communications 2023 11:157
  31. Plexiform neurofibroma (PN) is a leading cause of morbidity in children with the genetic condition Neurofibromatosis Type 1 (NF1), often disfiguring or threatening vital structures. During formation of PN, a c...

    Authors: Vladimir Amani, Kent A. Riemondy, Rui Fu, Andrea M. Griesinger, Enrique Grimaldo, Graziella Ribeiro De Sousa, Ahmed Gilani, Molly Hemenway, Nicholas K. Foreman, Andrew M. Donson and Nicholas Willard
    Citation: Acta Neuropathologica Communications 2023 11:158
  32. Although recent molecular analyses revealed that sporadic meningiomas have various genetic, epigenetic, and transcriptomic profiles, meningioma in patients with neurofibromatosis type 2 (NF2) have not been ful...

    Authors: Yu Teranishi, Satoru Miyawaki, Masahiro Nakatochi, Atsushi Okano, Kenta Ohara, Hiroki Hongo, Daiichiro Ishigami, Yu Sakai, Daisuke Shimada, Shunsaku Takayanagi, Masako Ikemura, Daisuke Komura, Hiroto Katoh, Jun Mitsui, Shinichi Morishita, Tetsuo Ushiku…
    Citation: Acta Neuropathologica Communications 2023 11:156
  33. Inflammasomes, primarily responsible for the activation of IL-1β, have emerged as critical regulators of the tumor microenvironment. By using in vivo and in vitro brain metastasis models, as well as human samp...

    Authors: Ádám Mészáros, Kinga Molnár, Csilla Fazakas, Bernát Nógrádi, Adél Lüvi, Tamás Dudás, László Tiszlavicz, Attila Elek Farkas, István Adorján Krizbai and Imola Wilhelm
    Citation: Acta Neuropathologica Communications 2023 11:155
  34. Astrocytes are a major category of glial support cell in the central nervous system and play a variety of essential roles in both health and disease. As our understanding of the diverse functions of these cell...

    Authors: Paul F. Cullen, Arpan G. Mazumder, Daniel Sun and John G. Flanagan
    Citation: Acta Neuropathologica Communications 2023 11:154
  35. One of the most significant challenges in patients with medulloblastoma is reducing the dose of craniospinal irradiation (CSI) to minimize neurological sequelae in survivors. Molecular characterization of pati...

    Authors: Kohei Fukuoka, Jun Kurihara, Tomoko Shofuda, Naoki Kagawa, Kai Yamasaki, Ryo Ando, Joji Ishida, Masayuki Kanamori, Atsufumi Kawamura, Young-Soo Park, Chikako Kiyotani, Takuya Akai, Dai Keino, Yosuke Miyairi, Atsushi Sasaki, Junko Hirato…
    Citation: Acta Neuropathologica Communications 2023 11:153
  36. Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease associated with repetitive head trauma. Brain pathology in CTE is characterized by neuronal loss, gliosis, and a distinctive pattern of neu...

    Authors: Ragini Phansalkar, Vanessa S. Goodwill, Jeffrey J. Nirschl, Chiara De Lillo, Jihee Choi, Elizabeth Spurlock, David G. Coughlin, Donald Pizzo, Christina J. Sigurdson, Annie Hiniker, Victor E. Alvarez, Ann C. Mckee and Jonathan H. Lin
    Citation: Acta Neuropathologica Communications 2023 11:152
  37. Motor neurons (MNs), which are primarily affected in amyotrophic lateral sclerosis (ALS), are a specialized type of neurons that are long and non-dividing. Given their unique structure, these cells heavily rel...

    Authors: Jimmy Beckers, Arun Kumar Tharkeshwar, Laura Fumagalli, Matilde Contardo, Evelien Van Schoor, Raheem Fazal, Dietmar Rudolf Thal, Siddharthan Chandran, Renzo Mancuso, Ludo Van Den Bosch and Philip Van Damme
    Citation: Acta Neuropathologica Communications 2023 11:151
  38. The hippocampus is a primary region affected in Alzheimer’s disease (AD). Because AD postmortem brain tissue is not available prior to symptomatic stage, we lack understanding of early cellular pathogenic mech...

    Authors: Yuriy Pomeshchik, Erika Velasquez, Jeovanis Gil, Oxana Klementieva, Ritha Gidlöf, Marie Sydoff, Silvia Bagnoli, Benedetta Nacmias, Sandro Sorbi, Gunilla Westergren-Thorsson, Gunnar K. Gouras, Melinda Rezeli and Laurent Roybon
    Citation: Acta Neuropathologica Communications 2023 11:150
  39. Lewy body (LB) pathology commonly occurs in individuals with Alzheimer’s disease (AD) pathology. However, it remains unclear which genetic risk factors underlie AD pathology, LB pathology, or AD-LB co-patholog...

    Authors: Seth Talyansky, Yann Le Guen, Nandita Kasireddy, Michael E. Belloy and Michael D. Greicius
    Citation: Acta Neuropathologica Communications 2023 11:149
  40. Authors: Osamu Yokota, Tomoko Miki, Hanae Nakashima-Yasuda, Hideki Ishizu, Takashi Haraguchi, Chikako Ikeda, Akinori Miyashita, Takeshi Ikeuchi, Shintaro Takenoshita, Seishi Terada and Manabu Takaki
    Citation: Acta Neuropathologica Communications 2023 11:148
  41. TSPO is a promising novel tracer target for positron-emission tomography (PET) imaging of brain tumors. However, due to the heterogeneity of cell populations that contribute to the TSPO-PET signal, imaging int...

    Authors: Lorraine Weidner, Julia Lorenz, Stefanie Quach, Frank K. Braun, Tanja Rothhammer-Hampl, Laura-Marie Ammer, Arabel Vollmann-Zwerenz, Laura M. Bartos, Franziska J. Dekorsy, Adrien Holzgreve, Sabrina V. Kirchleitner, Niklas Thon, Tobias Greve, Viktoria Ruf, Jochen Herms, Stefanie Bader…
    Citation: Acta Neuropathologica Communications 2023 11:147
  42. Retinal ganglion cells are highly metabolically active requiring strictly regulated metabolism and functional mitochondria to keep ATP levels in physiological range. Imbalances in metabolism and mitochondrial ...

    Authors: Alessio Canovai, James R. Tribble, Melissa Jöe, Daniela Y. Westerlund, Rosario Amato, Ian A. Trounce, Massimo Dal Monte and Pete A. Williams
    Citation: Acta Neuropathologica Communications 2023 11:146
  43. Among transmissible spongiform encephalopathies or prion diseases affecting humans, sporadic forms such as sporadic Creutzfeldt–Jakob disease are the vast majority. Unlike genetic or acquired forms of the dise...

    Authors: Hasier Eraña, Carlos M. Díaz-Domínguez, Jorge M. Charco, Enric Vidal, Ezequiel González-Miranda, Miguel A. Pérez-Castro, Patricia Piñeiro, Rafael López-Moreno, Cristina Sampedro-Torres-Quevedo, Leire Fernández-Veiga, Juan Tasis-Galarza, Nuria L. Lorenzo, Aileen Santini-Santiago, Melisa Lázaro, Sandra García-Martínez, Nuno Gonçalves-Anjo…
    Citation: Acta Neuropathologica Communications 2023 11:145
  44. Mild traumatic brain injury (mTBI) induced by low-intensity blast (LIB) is a serious health problem affecting military service members and veterans. Our previous reports using a single open-field LIB mouse mod...

    Authors: Chao Li, Shanyan Chen, Heather R. Siedhoff, DeAna Grant, Pei Liu, Ashley Balderrama, Marcus Jackson, Amitai Zuckerman, C. Michael Greenlief, Firas Kobeissy, Kevin W. Wang, Ralph G. DePalma, Ibolja Cernak, Jiankun Cui and Zezong Gu
    Citation: Acta Neuropathologica Communications 2023 11:144
  45. Diffuse gliomas are a heterogeneous category of primary central nervous system tumors. Due to their infiltrative growth precluding complete surgical resection, most diffuse high-grade gliomas are treated with ...

    Authors: Matthew D. Wood, Carol Beadling, Tanaya Neff, Steve Moore, Christina A. Harrington, Lissa Baird and Christopher Corless
    Citation: Acta Neuropathologica Communications 2023 11:143
  46. Dystrophic neurites (DNs) are abnormal axons and dendrites that are swollen or deformed in various neuropathological conditions. In Alzheimer’s disease (AD), DNs play a crucial role in impairing neuronal commu...

    Authors: Jaemyung Jang, Seungeun Yeo, Soonbong Baek, Hyun Jin Jung, Mi Suk Lee, Seung Hee Choi and Youngshik Choe
    Citation: Acta Neuropathologica Communications 2023 11:142
  47. The MV1 and MV2 subtypes of sporadic Creutzfeldt–Jakob disease (sCJD) are linked to the heterozygous methionine (M)/valine (V) polymorphism at codon 129 of the prion protein (PrP) gene. MV2 is phenotypically h...

    Authors: Laura Cracco, Gianfranco Puoti, Antonio Cornacchia, Katie Glisic, Seong‑Ki Lee, Zerui Wang, Mark L. Cohen, Brian S. Appleby and Ignazio Cali
    Citation: Acta Neuropathologica Communications 2023 11:141
  48. G4C2 hexanucleotide repeat expansions in a non-coding region of the C9orf72 gene are the most common cause of familial amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). G4C2 insertion length ...

    Authors: Javier Morón-Oset, Lilly Katharina Sophie Fischer, Nathalie Jauré, Pingze Zhang, Annika Julia Jahn, Tessa Supèr, André Pahl, Adrian M. Isaacs, Sebastian Grönke and Linda Partridge
    Citation: Acta Neuropathologica Communications 2023 11:140

Annual Journal Metrics

  • 2022 Citation Impact
    7.1 - 2-year Impact Factor
    7.8 - 5-year Impact Factor
    1.289 - SNIP (Source Normalized Impact per Paper)
    2.395 - SJR (SCImago Journal Rank)

    2023 Speed
    3 days submission to first editorial decision for all manuscripts (Median)
    50 days submission to accept (Median)

    2023 Usage
    1,631,164 downloads
    3,652 Altmetric mentions