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  1. Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative condition associated with repetitive traumatic brain injury (rTBI) seen in contact-sport athletes and military personnel. The medial te...

    Authors: Christy M. Kelley, Sylvia E. Perez and Elliott J. Mufson

    Citation: Acta Neuropathologica Communications 2019 7:207

    Content type: Research

    Published on:

  2. Aldehyde dehydrogenase 2 deficiency (ALDH2*2) causes facial flushing in response to alcohol consumption in approximately 560 million East Asians. Recent meta-analysis demonstrated the potential link between AL...

    Authors: Amit U. Joshi, Lauren D. Van Wassenhove, Kelsey R. Logas, Paras S. Minhas, Katrin I. Andreasson, Kenneth I. Weinberg, Che-Hong Chen and Daria Mochly-Rosen

    Citation: Acta Neuropathologica Communications 2019 7:190

    Content type: Research

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  3. Multiple Sclerosis (MS) is the most common cause of acquired neurological disability in young adults, pathologically characterized by leukocyte infiltration of the central nervous system, demyelination of the ...

    Authors: Thecla A. van Wageningen, Eva Vlaar, Gijs Kooij, Cornelis A. M. Jongenelen, Jeroen J. G. Geurts and Anne-Marie van Dam

    Citation: Acta Neuropathologica Communications 2019 7:206

    Content type: Research

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  4. To identify pathogenetic markers and potential drivers of different lesion types in the white matter (WM) of patients with progressive multiple sclerosis (PMS), we sequenced RNA from 73 different WM areas. Com...

    Authors: Maria L. Elkjaer, Tobias Frisch, Richard Reynolds, Tim Kacprowski, Mark Burton, Torben A. Kruse, Mads Thomassen, Jan Baumbach and Zsolt Illes

    Citation: Acta Neuropathologica Communications 2019 7:205

    Content type: Research

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  5. Alzheimer disease (AD) is a neurodegenerative disorder characterized pathologically by the accumulation of amyloid-beta (Aβ) plaques and tau neurofibrillary tangles (NFTs). Recently, primary age-related tauopa...

    Authors: Miguel Quintas-Neves, Merilee A. Teylan, Lilah Besser, João Soares-Fernandes, Charles N. Mock, Walter A. Kukull, John F. Crary and Tiago Gil Oliveira

    Citation: Acta Neuropathologica Communications 2019 7:204

    Content type: Research

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  6. Many mouse models of Alzheimer’s disease (AD) exhibit impairments in hippocampal long-term-potentiation (LTP), seemingly corroborating the strong correlation between synaptic loss and cognitive decline reporte...

    Authors: Enrico Faldini, Tariq Ahmed, Luc Bueé, David Blum and Detlef Balschun

    Citation: Acta Neuropathologica Communications 2019 7:202

    Content type: Research

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  7. The presence of genome-wide DNA hypermethylation is a hallmark of lower grade gliomas (LGG) with isocitrate dehydrogenase (IDH) mutations. Further molecular classification of IDH mutant gliomas is defined by t...

    Authors: Ruslan Al-Ali, Katharina Bauer, Jong-Whi Park, Ruba Al Abdulla, Valentina Fermi, Andreas von Deimling, Christel Herold-Mende, Jan-Philipp Mallm, Carl Herrmann, Wolfgang Wick and Şevin Turcan

    Citation: Acta Neuropathologica Communications 2019 7:201

    Content type: Research

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  8. Damage to axonal transport is an early pathogenic event in Alzheimer’s disease. The amyloid precursor protein (APP) is a key axonal transport cargo since disruption to APP transport promotes amyloidogenic proc...

    Authors: Gábor M. Mórotz, Elizabeth B. Glennon, Jenny Greig, Dawn H. W. Lau, Nishita Bhembre, Francesca Mattedi, Nadine Muschalik, Wendy Noble, Alessio Vagnoni and Christopher C. J. Miller

    Citation: Acta Neuropathologica Communications 2019 7:200

    Content type: Research

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  9. CREB (cyclic AMP response element binding protein) binding protein (CBP, CREBBP) is a ubiquitously expressed transcription coactivator with intrinsic histone acetyltransferase (KAT) activity. Germline mutation...

    Authors: Melanie Schoof, Michael Launspach, Dörthe Holdhof, Lynhda Nguyen, Verena Engel, Severin Filser, Finn Peters, Jana Immenschuh, Malte Hellwig, Judith Niesen, Volker Mall, Birgit Ertl-Wagner, Christian Hagel, Michael Spohn, Beat Lutz, Jan Sedlacik…

    Citation: Acta Neuropathologica Communications 2019 7:199

    Content type: Research

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  10. Aβ-amyloid deposition is a key feature of Alzheimer’s disease, but Consortium to Establish a Registry for Alzheimer's Disease (CERAD) assessment, based on neuritic plaque density, shows a limited relationships...

    Authors: S. B. Wharton, D. Wang, C. Parikh, F. E. Matthews, C. Brayne and P. G. Ince

    Citation: Acta Neuropathologica Communications 2019 7:198

    Content type: Research

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  11. Protein aggregation is a pathological feature of neurodegenerative disorders. We previously demonstrated that protein inclusions in the brain are composed of supersaturated proteins, which are abundant and agg...

    Authors: Prajwal Ciryam, Matthew Antalek, Fernando Cid, Gian Gaetano Tartaglia, Christopher M. Dobson, Anne-Katrin Guettsches, Britta Eggers, Matthias Vorgerd, Katrin Marcus, Rudolf A. Kley, Richard I. Morimoto, Michele Vendruscolo and Conrad C. Weihl

    Citation: Acta Neuropathologica Communications 2019 7:197

    Content type: Research

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  12. Rett Syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG binding protein 2 (MECP2) gene. Deficient K+-Clco-transporter 2 (KCC2) expression is suggested to play a key role in the...

    Authors: Lisa Hinz, Joan Torrella Barrufet and Vivi M. Heine

    Citation: Acta Neuropathologica Communications 2019 7:196

    Content type: Case report

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  13. We recently identified Secernin-1 (SCRN1) as a novel amyloid plaque associated protein using localized proteomics. Immunohistochemistry studies confirmed that SCRN1 was present in plaque-associated dystrophic ...

    Authors: Geoffrey Pires, Sacha McElligott, Shiron Drusinsky, Glenda Halliday, Marie-Claude Potier, Thomas Wisniewski and Eleanor Drummond

    Citation: Acta Neuropathologica Communications 2019 7:195

    Content type: Research

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  14. An impairment of amyloid β-peptide (Aβ) clearance is suggested to play a key role in the pathogenesis of sporadic Alzheimer’s disease (AD). Amyloid degradation is mediated by various mechanisms including fragm...

    Authors: Tunahan Kirabali, Serena Rigotti, Alessandro Siccoli, Filip Liebsch, Adeola Shobo, Christoph Hock, Roger M. Nitsch, Gerhard Multhaup and Luka Kulic

    Citation: Acta Neuropathologica Communications 2019 7:194

    Content type: Research

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  15. Synucleinopathies [Parkinson’s disease with or without dementia, dementia with Lewy bodies and multiple system atrophy] are neurodegenerative diseases that are defined by the presence of filamentous α-synuclei...

    Authors: Therése Klingstedt, Bernardino Ghetti, Janice L. Holton, Helen Ling, K. Peter R. Nilsson and Michel Goedert

    Citation: Acta Neuropathologica Communications 2019 7:193

    Content type: Research

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  16. Tau is a microtubule-binding protein that can receive various post-translational modifications (PTMs) including phosphorylation, methylation, acetylation, glycosylation, nitration, sumoylation and truncation. ...

    Authors: Ebru Ercan-Herbst, Jens Ehrig, David C. Schöndorf, Annika Behrendt, Bernd Klaus, Borja Gomez Ramos, Nuria Prat Oriol, Christian Weber and Dagmar E. Ehrnhoefer

    Citation: Acta Neuropathologica Communications 2019 7:192

    Content type: Research

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  17. The contribution of mosaic alterations to tumors of the nervous system and to non-malignant neurological diseases has been unmasked thanks to the development of Next Generation Sequencing (NGS) technologies. W...

    Authors: Alice Goldenberg, Florent Marguet, Vianney Gilard, Aude-Marie Cardine, Adnan Hassani, François Doz, Sophie Radi, Stéphanie Vasseur, Jacqueline Bou, Maud Branchaud, Claude Houdayer, Stéphanie Baert-Desurmont, Annie Laquerriere and Thierry Frebourg

    Citation: Acta Neuropathologica Communications 2019 7:191

    Content type: Case report

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  18. Motor-, behavior- and/or cognition-related symptoms are key hallmarks in patients with amyotrophic lateral sclerosis (ALS) and frontotemporal lobar degeneration (FTLD) with TDP-43 pathology (FTLD-TDP), respect...

    Authors: Lieselot Dedeene, Evelien Van Schoor, Rik Vandenberghe, Philip Van Damme, Koen Poesen and Dietmar Rudolf Thal

    Citation: Acta Neuropathologica Communications 2019 7:189

    Content type: Research

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  19. Recent work has highlighted the tumor microenvironment as a central player in cancer. In particular, interactions between tumor and immune cells may help drive the development of brain tumors such as glioblast...

    Authors: Maria Martinez-Lage, Timothy M. Lynch, Yingtao Bi, Carolina Cocito, Gregory P. Way, Sharmistha Pal, Josephine Haller, Rachel E. Yan, Amy Ziober, Aivi Nguyen, Manoj Kandpal, Donald M. O’Rourke, Jeffrey P. Greenfield, Casey S. Greene, Ramana V. Davuluri and Nadia Dahmane

    Citation: Acta Neuropathologica Communications 2019 7:203

    Content type: Research

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  20. Swedish type Hereditary Diffuse Leukoencephalopathy with Spheroids (HDLS-S) is a severe adult-onset leukoencephalopathy with the histopathological hallmark of neuraxonal degeneration with spheroids, described ...

    Authors: Christina Sundal, Susana Carmona, Maria Yhr, Odd Almström, Maria Ljungberg, John Hardy, Carola Hedberg-Oldfors, Åsa Fred, José Brás, Anders Oldfors, Oluf Andersen and Rita Guerreiro

    Citation: Acta Neuropathologica Communications 2019 7:188

    Content type: Research

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  21. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic paradigm of small vessel disease (SVD) caused by NOTCH3 mutations that stereotypically lead to the...

    Authors: Rikesh M. Rajani, Julien Ratelade, Valérie Domenga-Denier, Yoshiki Hase, Hannu Kalimo, Raj N. Kalaria and Anne Joutel

    Citation: Acta Neuropathologica Communications 2019 7:187

    Content type: Research

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  22. Numerous clinical studies have established the debilitating neurocognitive side effects of chemotherapy in the treatment of breast cancer, often referred as chemobrain. We hypothesize that cognitive impairment...

    Authors: Barrett D. Allen, Lauren A. Apodaca, Amber R. Syage, Mineh Markarian, Al Anoud D. Baddour, Harutyun Minasyan, Leila Alikhani, Celine Lu, Brian L. West, Erich Giedzinski, Janet E. Baulch and Munjal M. Acharya

    Citation: Acta Neuropathologica Communications 2019 7:186

    Content type: Research

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  23. Many biology-based precision drugs are available that neutralize aberrant molecular pathways in cancer. Molecular heterogeneity and the lack of reliable companion diagnostic biomarkers for many drugs makes tar...

    Authors: Krissie Lenting, Corina N. A. M. van den Heuvel, Anne van Ewijk, Duaa ElMelik, Remco de Boer, Elizabeth Tindall, Ge Wei, Benno Kusters, Maarten te Dorsthorst, Mark ter Laan, Martijn A. Huynen and William P. Leenders

    Citation: Acta Neuropathologica Communications 2019 7:185

    Content type: Research

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  24. Targeting alpha-synuclein (α-syn) as a therapeutic strategy for Parkinson’s disease (PD) has been intensively pursued largely due to its well-recognized pathogenic role. Since its discovery as the first famili...

    Authors: Rebecca Z. Fan, Min Guo, Shouqing Luo, Mei Cui and Kim Tieu

    Citation: Acta Neuropathologica Communications 2019 7:184

    Content type: Research

    Published on:

  25. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). While the clinical presentation of LRRK2 mutation carriers is similar to that of idiopathic PD (iP...

    Authors: Michael X. Henderson, Medha Sengupta, John Q. Trojanowski and Virginia M. Y. Lee

    Citation: Acta Neuropathologica Communications 2019 7:183

    Content type: Research

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  26. Mild traumatic brain injury (mTBI) leads to diverse symptoms including mood disorders, cognitive decline, and behavioral changes. In some individuals, these symptoms become chronic and persist in the long-term...

    Authors: Nicole Schwab, Karl Grenier and Lili-Naz Hazrati

    Citation: Acta Neuropathologica Communications 2019 7:182

    Content type: Research

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  27. Risk stratification of children with ependymomas of the posterior fossa in current therapeutic protocols is mainly based on clinical criteria. We aimed to identify independent outcome predictors for this disea...

    Authors: Stephanie T. Jünger, Martin Mynarek, Inken Wohlers, Evelyn Dörner, Anja zur Mühlen, Natalia Velez-Char, Katja von Hoff, Stefan Rutkowski, Monika Warmuth-Metz, Rolf-Dieter Kortmann, Beate Timmermann, Sven Rahmann, Ludger Klein-Hitpass, Andre O. von Bueren and Torsten Pietsch

    Citation: Acta Neuropathologica Communications 2019 7:181

    Content type: Research

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  28. Alzheimer’s disease (AD) is the most common form of dementia in the elderly. According to the amyloid hypothesis, the accumulation and deposition of amyloid-beta (Aβ) peptides play a key role in AD. Soluble Aβ...

    Authors: Inès R. H. Ben-Nejma, Aneta J. Keliris, Jasmijn Daans, Peter Ponsaerts, Marleen Verhoye, Annemie Van der Linden and Georgios A. Keliris

    Citation: Acta Neuropathologica Communications 2019 7:180

    Content type: Research

    Published on:

  29. In the original version of this article [1], there was 1 error in the affiliation of the European Institute of Oncology (affiliation 3). In this correction article the updated affiliation is shown for clarific...

    Authors: Ashirwad Merve, Xinyu Zhang, Nicola Pomella, Serena Acquati, Joerg D. Hoeck, Anaelle Dumas, Gabriel Rosser, Yichen Li, Jennie Jeyapalan, Silvia Vicenzi, Qianhai Fan, Zeng Jie Yang, Arianna Sabò, Denise Sheer, Axel Behrens and Silvia Marino

    Citation: Acta Neuropathologica Communications 2019 7:179

    Content type: Correction

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    The original article was published in Acta Neuropathologica Communications 2019 7:95

  30. Alzheimer’s disease (AD)-related amyloid β-peptide (Aβ) pathology in the form of amyloid plaques and cerebral amyloid angiopathy (CAA) spreads in its topographical distribution, increases in quantity, and unde...

    Authors: Dietmar Rudolf Thal, Alicja Ronisz, Thomas Tousseyn, Ajeet Rijal Upadhaya, Karthikeyan Balakrishnan, Rik Vandenberghe, Mathieu Vandenbulcke, Christine A. F. von Arnim, Markus Otto, Thomas G. Beach, Johan Lilja, Kerstin Heurling, Aruna Chakrabarty, Azzam Ismail, Christopher Buckley, Adrian P. L. Smith…

    Citation: Acta Neuropathologica Communications 2019 7:178

    Content type: Research

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  31. Intraneuronal insoluble inclusions made of Tau protein are neuropathological hallmarks of Alzheimer Disease (AD). Cleavage of Tau by legumain (LGMN) has been proposed to be crucial for aggregation of Tau into ...

    Authors: Kerstin Schlegel, Khader Awwad, Roland G. Heym, David Holzinger, Annika Doell, Stefan Barghorn, Thomas R. Jahn, Corinna Klein, Yulia Mordashova, Michael Schulz and Laura Gasparini

    Citation: Acta Neuropathologica Communications 2019 7:177

    Content type: Research

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  32. Authors: Arnault Tauziède-Espariat, Mélanie Pagès, Alexandre Roux, Aurore Siegfried, Emmanuelle Uro-Coste, Yvan Nicaise, Annick Sevely, Marion Gambart, Sergio Boetto, Martin Dupuy, Pomone Richard, Romain Perbet, Matthieu Vinchon, Sabine Caron, Felipe Andreiuolo, Albane Gareton…

    Citation: Acta Neuropathologica Communications 2019 7:176

    Content type: Letter to the Editor

    Published on:

  33. All cancer cells need to maintain functional telomeres to sustain continuous cell division and proliferation. In human diffuse gliomas, functional telomeres are maintained due either to reactivation of telomer...

    Authors: Nathalie Grandin, Bruno Pereira, Camille Cohen, Pauline Billard, Caroline Dehais, Catherine Carpentier, Ahmed Idbaih, Franck Bielle, François Ducray, Dominique Figarella-Branger, Jean-Yves Delattre, Marc Sanson, Patrick Lomonte, Delphine Poncet, Pierre Verrelle and Michel Charbonneau

    Citation: Acta Neuropathologica Communications 2019 7:175

    Content type: Research

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  34. Microglial function is highly dependent on cell motility, with baseline motility required for homeostatic surveillance activity and directed motility to migrate towards a source of injury. Experimental evidenc...

    Authors: Diana K. Franco-Bocanegra, Bethany George, Laurie C. Lau, Clive Holmes, James A. R. Nicoll and Delphine Boche

    Citation: Acta Neuropathologica Communications 2019 7:174

    Content type: Research

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  35. Adolescent binge drinking represents a major public health challenge and can lead to persistent neurological and mental conditions, but the underlying pathogenic mechanisms remain poorly understood. Using a mo...

    Authors: James Rice, Laurence Coutellier, Jeffrey L. Weiner and Chen Gu

    Citation: Acta Neuropathologica Communications 2019 7:173

    Content type: Research

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  36. Non-tumoural cells within the tumour microenvironment (TME) influence tumour proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary neuroendocrine tumours (PitNETs). We aimed to c...

    Authors: Pedro Marques, Sayka Barry, Eivind Carlsen, David Collier, Amy Ronaldson, Sherine Awad, Neil Dorward, Joan Grieve, Nigel Mendoza, Samiul Muquit, Ashley B. Grossman, Frances Balkwill and Márta Korbonits

    Citation: Acta Neuropathologica Communications 2019 7:172

    Content type: Research

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  37. The detection of amyloid beta deposits and neurofibrillary tangles, both hallmarks of Alzheimer’s disease (AD), is key to understanding the mechanisms underlying these pathologies. Luminescent conjugated oligo...

    Authors: Maria Calvo-Rodriguez, Steven S. Hou, Austin C. Snyder, Simon Dujardin, Hamid Shirani, K. Peter R. Nilsson and Brian J. Bacskai

    Citation: Acta Neuropathologica Communications 2019 7:171

    Content type: Research

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  38. Although it has been suggested that the co-expression of multiple pathological proteins associated with neurodegeneration may act synergistically to induce more widespread neuropathology, experimental evidence...

    Authors: Alexander J. Moszczynski, Madeline Harvey, Niveen Fulcher, Cleusa de Oliveira, Patrick McCunn, Neil Donison, Robert Bartha, Susanne Schmid, Michael J. Strong and Kathryn Volkening

    Citation: Acta Neuropathologica Communications 2019 7:170

    Content type: Research

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  39. To date, the development of disease-modifying therapies for Alzheimer’s disease (AD) has largely focused on the removal of amyloid beta Aβ fragments from the CNS. Proteomic profiling of patient fluids may help...

    Authors: Christopher D. Whelan, Niklas Mattsson, Michael W. Nagle, Swetha Vijayaraghavan, Craig Hyde, Shorena Janelidze, Erik Stomrud, Julie Lee, Lori Fitz, Tarek A. Samad, Gayathri Ramaswamy, Richard A. Margolin, Anders Malarstig and Oskar Hansson

    Citation: Acta Neuropathologica Communications 2019 7:169

    Content type: Research

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  40. The family of juvenile xanthogranuloma family neoplasms (JXG) with ERK-pathway mutations are now classified within the “L” (Langerhans) group, which includes Langerhans cell histiocytosis (LCH) and Erdheim Che...

    Authors: J. Picarsic, T. Pysher, H. Zhou, M. Fluchel, T. Pettit, M. Whitehead, L. F. Surrey, B. Harding, G. Goldstein, Y. Fellig, M. Weintraub, B. C. Mobley, P. M. Sharples, M. L. Sulis, E. L. Diamond, R. Jaffe…

    Citation: Acta Neuropathologica Communications 2019 7:168

    Content type: Research

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  41. Co-occurrence of multiple neuropathologic changes is a common phenomenon, most prominently seen in Alzheimer’s disease (AD) and Parkinson’s disease (PD), complicating clinical diagnosis and patient management....

    Authors: Amanda N. Sacino, Stefan Prokop, Meggen A. Walsh, Jennifer Adamson, S. H. Subramony, Amy Krans, Peter K. Todd, Benoit I. Giasson and Anthony T. Yachnis

    Citation: Acta Neuropathologica Communications 2019 7:158

    Content type: Case report

    Published on:

  42. CGG repeat expansions in FMR1 cause the neurodegenerative disorder Fragile X-associated Tremor/Ataxia Syndrome (FXTAS). Ubiquitinated neuronal intranuclear inclusions (NIIs) are the neuropathological hallmark of ...

    Authors: Amy Krans, Geena Skariah, Yuan Zhang, Bryana Bayly and Peter K. Todd

    Citation: Acta Neuropathologica Communications 2019 7:152

    Content type: Research

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  43. Glycogen storage disorder type III (GSDIII), or debranching enzyme (GDE) deficiency, is a rare metabolic disorder characterized by variable liver, cardiac, and skeletal muscle involvement. GSDIII manifests wit...

    Authors: Pascal Laforêt, Michio Inoue, Evelyne Goillot, Claire Lefeuvre, Umut Cagin, Nathalie Streichenberger, Sarah Leonard-Louis, Guy Brochier, Angeline Madelaine, Clemence Labasse, Carola Hedberg-Oldfors, Thomas Krag, Louisa Jauze, Julien Fabregue, Philippe Labrune, Jose Milisenda…

    Citation: Acta Neuropathologica Communications 2019 7:167

    Content type: Research

    Published on:

  44. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition that primarily affects the motor system and shares many features with frontotemporal dementia (FTD). Evidence suggests that ALS is a ‘...

    Authors: Matthew A. White, Ziqiang Lin, Eugene Kim, Christopher M. Henstridge, Emiliano Pena Altamira, Camille K. Hunt, Ella Burchill, Isobel Callaghan, Andrea Loreto, Heledd Brown-Wright, Richard Mead, Camilla Simmons, Diana Cash, Michael P. Coleman and Jemeen Sreedharan

    Citation: Acta Neuropathologica Communications 2019 7:166

    Content type: Research

    Published on:

  45. Amyotrophic lateral sclerosis (ALS) is characterized pathologically by the occurrence of phosphorylated TDP-43 (pTDP-43)-immunoreactive neuronal and glial inclusions in the central nervous system. Recent studi...

    Authors: Fumiaki Mori, Mari Tada, Tomoya Kon, Yasuo Miki, Kunikazu Tanji, Hidekachi Kurotaki, Masahiko Tomiyama, Tomohiko Ishihara, Osamu Onodera, Akiyoshi Kakita and Koichi Wakabayashi

    Citation: Acta Neuropathologica Communications 2019 7:165

    Content type: Research

    Published on:

  46. Chronic traumatic encephalopathy (CTE) is a tauopathy associated to repetitive head trauma. There are no validated in vivo biomarkers of CTE and a definite diagnosis can only be made at autopsy. Recent studies...

    Authors: Marta Marquié, Cinthya Agüero, Ana C. Amaral, Alberto Villarejo-Galende, Prianca Ramanan, Michael Siao Tick Chong, Nil Sáez-Calveras, Rachel E. Bennett, Eline E. Verwer, Sally Ji Who Kim, Maeva Dhaynaut, Victor E. Alvarez, Keith A. Johnson, Ann C. McKee, Matthew P. Frosch and Teresa Gómez-Isla

    Citation: Acta Neuropathologica Communications 2019 7:164

    Content type: Research

    Published on:

  47. In this multi-institutional study we compiled a retrospective cohort of 86 posterior fossa tumors having received the diagnosis of cerebellar glioblastoma (cGBM). All tumors were reviewed histologically and su...

    Authors: Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Christian Koelsche, Annika K. Wefers, Azadeh Ebrahimi, Philipp Sievers, Kristin Huang, M. Belén Casalini, Francisco Fernández-Klett, Abigail Suwala, Michael Weller, Dorothee Gramatzki, Joerg Felsberg, Guido Reifenberger, Albert Becker…

    Citation: Acta Neuropathologica Communications 2019 7:163

    Content type: Research

    Published on:

  48. For the proper organization of the six-layered mammalian neocortex it is required that neurons migrate radially from their place of birth towards their designated destination. The molecular machinery underlyin...

    Authors: Lena Will, Sybren Portegies, Jasper van Schelt, Merel van Luyk, Dick Jaarsma and Casper C. Hoogenraad

    Citation: Acta Neuropathologica Communications 2019 7:162

    Content type: Research

    Published on:

  49. A hexanucleotide repeat expansion in a noncoding region of C9orf72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Reduction of select or total C9orf72 t...

    Authors: Shangxi Xiao, Paul M. McKeever, Agnes Lau and Janice Robertson

    Citation: Acta Neuropathologica Communications 2019 7:161

    Content type: Research

    Published on:

  50. Tau aggregation is a hallmark feature in a subset of patients with frontotemporal dementia (FTD). Early and selective loss of von Economo neurons (VENs) and fork cells within the frontoinsular (FI) and anterio...

    Authors: Li-Chun Lin, Alissa L. Nana, Mackenzie Hepker, Ji-Hye Lee Hwang, Stephanie E. Gaus, Salvatore Spina, Celica G. Cosme, Li Gan, Lea T. Grinberg, Daniel H. Geschwind, Giovanni Coppola, Howard J. Rosen, Bruce L. Miller and William W. Seeley

    Citation: Acta Neuropathologica Communications 2019 7:159

    Content type: Research

    Published on:

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