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  1. In humans, iatrogenic transmission of cerebral amyloid-β (Aβ)-amyloidosis is suspected following inoculation of pituitary-derived hormones or dural grafts presumably contaminated with Aβ proteins as well as af...

    Authors: Anne-Sophie Hérard, Fanny Petit, Charlotte Gary, Martine Guillermier, Susana Boluda, Clément M. Garin, Suzanne Lam and Marc Dhenain

    Citation: Acta Neuropathologica Communications 2020 8:205

    Content type: Research

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  2. Oculopharyngodistal myopathy (OPDM) is a rare hereditary muscle disease characterized by progressive distal limb weakness, ptosis, ophthalmoplegia, bulbar muscle weakness and rimmed vacuoles on muscle biopsy. ...

    Authors: Masashi Ogasawara, Aritoshi Iida, Theerawat Kumutpongpanich, Ayami Ozaki, Yasushi Oya, Hirofumi Konishi, Akinori Nakamura, Ryuta Abe, Hiroshi Takai, Ritsuko Hanajima, Hiroshi Doi, Fumiaki Tanaka, Hisayoshi Nakamura, Ikuya Nonaka, Zhaoxia Wang, Shinichiro Hayashi…

    Citation: Acta Neuropathologica Communications 2020 8:204

    Content type: Research

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  3. Recurrent RELA and YAP1 fusions are intimately associated with tumorigenesis in supratentorial ependymomas. Chromothripsis and focal copy number alterations involving 11q are hallmarks of these tumors. However, i...

    Authors: Mutsumi Takadera, Kaishi Satomi, Frank Szulzewsky, Patrick J. Cimino, Eric C. Holland, Tetsuya Yamamoto, Koichi Ichimura and Tatsuya Ozawa

    Citation: Acta Neuropathologica Communications 2020 8:203

    Content type: Research

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  4. Extensive effort has been made studying retinal pathology in Alzheimer’s disease (AD) to improve early noninvasive diagnosis and treatment. Particularly relevant are vascular changes, which appear prominent in...

    Authors: Haoshen Shi, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Kolja Wawrowsky, Shouri Lahiri, Keith L. Black and Maya Koronyo-Hamaoui

    Citation: Acta Neuropathologica Communications 2020 8:202

    Content type: Research

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  5. TERT promoter mutations are commonly associated with 1p/19q codeletion in IDH-mutated gliomas. However, whether these mutations have an impact on patient survival independent of 1p/19q codeletion is unknown. In t...

    Authors: Hideyuki Arita, Yuko Matsushita, Ryunosuke Machida, Kai Yamasaki, Nobuhiro Hata, Makoto Ohno, Shigeru Yamaguchi, Takashi Sasayama, Shota Tanaka, Fumi Higuchi, Toshihiko Iuchi, Kuniaki Saito, Masayuki Kanamori, Ken-ichiro Matsuda, Yohei Miyake, Kaoru Tamura…

    Citation: Acta Neuropathologica Communications 2020 8:201

    Content type: Research

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  6. The kinase TTBK1 is predominantly expressed in the central nervous system and has been implicated in neurodegenerative diseases including Alzheimer’s disease, frontotemporal lobar degeneration, and amyotrophic...

    Authors: Pamela McMillan, Jeanna Wheeler, Rachel E. Gatlin, Laura Taylor, Tim Strovas, Misa Baum, Thomas D. Bird, Caitlin Latimer, C. Dirk Keene, Brian C. Kraemer and Nicole F. Liachko

    Citation: Acta Neuropathologica Communications 2020 8:200

    Content type: Research

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  7. The highly neurotropic rabies virus (RABV) enters peripheral neurons at axon termini and requires long distance axonal transport and trans-synaptic spread between neurons for the infection of the central nervo...

    Authors: Madlin Potratz, Luca M. Zaeck, Carlotta Weigel, Antonia Klein, Conrad M. Freuling, Thomas Müller and Stefan Finke

    Citation: Acta Neuropathologica Communications 2020 8:199

    Content type: Research

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  8. The brain pathology of Alzheimer’s disease (AD) is characterized by the misfolding and aggregation of both the amyloid beta (Aβ) peptide and hyperphosphorylated forms of the tau protein. Initial Aβ deposition ...

    Authors: Vanessa Laversenne, Sameer Nazeeruddin, Emma C. Källstig, Philippe Colin, Christel Voize and Bernard L. Schneider

    Citation: Acta Neuropathologica Communications 2020 8:198

    Content type: Research

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  9. In addition to its role as an auxiliary subunit of A-type voltage-gated K+ channels, we have previously reported that the single transmembrane protein Dipeptidyl Peptidase Like 6 (DPP6) impacts neuronal and synap...

    Authors: Lin Lin, Ronald S. Petralia, Ross Lake, Ya-Xian Wang and Dax A. Hoffman

    Citation: Acta Neuropathologica Communications 2020 8:197

    Content type: Research

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  10. Alpha-synuclein is the main protein component of Lewy bodies, the pathological hallmark of Parkinson’s disease. However, genetic modifiers of cerebrospinal fluid (CSF) alpha-synuclein levels remain unknown. Th...

    Authors: Laura Ibanez, Jorge A. Bahena, Chengran Yang, Umber Dube, Fabiana H. G. Farias, John P. Budde, Kristy Bergmann, Carol Brenner-Webster, John C. Morris, Richard J. Perrin, Nigel J. Cairns, John O’Donnell, Ignacio Álvarez, Monica Diez-Fairen, Miquel Aguilar, Rebecca Miller…

    Citation: Acta Neuropathologica Communications 2020 8:196

    Content type: Research

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  11. Considering its intolerance to ischemia, it is of critical importance for the brain to efficiently process microvascular occlusions and maintain tissue perfusion. In addition to collateral microvascular flow a...

    Authors: Anne-Eva van der Wijk, Theodosia Georgakopoulou, Jisca Majolée, Jan S. M. van Bezu, Miesje M. van der Stoel, Bert J. van het Hof, Helga E. de Vries, Stephan Huveneers, Peter L. Hordijk, Erik N. T. P. Bakker and Ed van Bavel

    Citation: Acta Neuropathologica Communications 2020 8:195

    Content type: Research

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  12. Sanfilippo syndrome is an untreatable form of childhood-onset dementia. Whilst several therapeutic strategies are being evaluated in human clinical trials including i.v. delivery of AAV9-based gene therapy, an...

    Authors: Helen Beard, Glyn Chidlow, Daniel Neumann, Nazzmer Nazri, Meghan Douglass, Paul J. Trim, Marten F. Snel, Robert J. Casson and Kim M. Hemsley

    Citation: Acta Neuropathologica Communications 2020 8:194

    Content type: Research

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  13. Frequently reported neurotoxic sequelae of cancer treatment include cognitive deficits and sensorimotor abnormalities that have long-lasting negative effects on the quality of life of an increasing number of c...

    Authors: Angie C. A. Chiang, Alexandre V. Seua, Pooja Singhmar, Luis D. Arroyo, Rajasekaran Mahalingam, Jian Hu, Annemieke Kavelaars and Cobi J. Heijnen

    Citation: Acta Neuropathologica Communications 2020 8:193

    Content type: Research

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  14. Mutations in the RYR1 gene, encoding the skeletal muscle calcium channel RyR1, lead to congenital myopathies, through expression of a channel with abnormal permeability and/or in reduced amount, but the direct fu...

    Authors: Laurent Pelletier, Anne Petiot, Julie Brocard, Benoit Giannesini, Diane Giovannini, Colline Sanchez, Lauriane Travard, Mathilde Chivet, Mathilde Beaufils, Candice Kutchukian, David Bendahan, Daniel Metzger, Clara Franzini Armstrong, Norma B. Romero, John Rendu, Vincent Jacquemond…

    Citation: Acta Neuropathologica Communications 2020 8:192

    Content type: Research

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  15. Adult medulloblastomas are clinically and molecularly understudied due to their rarity. We performed molecular grouping, targeted sequencing, and TERT promoter Sanger sequencing on a cohort of 99 adult medullo...

    Authors: Gabriel Chun-Hei Wong, Kay Ka-Wai Li, Wei-Wei Wang, Anthony Pak-Yin Liu, Queenie Junqi Huang, Aden Ka-Yin Chan, Manix Fung-Man Poon, Nellie Yuk-Fei Chung, Queenie Hoi-Wing Wong, Hong Chen, Danny Tat Ming Chan, Xian-Zhi Liu, Ying Mao, Zhen-Yu Zhang, Zhi-Feng Shi and Ho-Keung Ng

    Citation: Acta Neuropathologica Communications 2020 8:191

    Content type: Research

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  16. The purpose of this study was to analyze the impact of copy number variations (CNV) on sporadic pituitary neuroendocrine tumors (PitNETs) prognosis, to identify specific prognosis markers according to the know...

    Authors: Hélène Lasolle, Mad-Hélénie Elsensohn, Anne Wierinckx, Eudeline Alix, Clément Bonnefille, Alexandre Vasiljevic, Christine Cortet, Bénédicte Decoudier, Nathalie Sturm, Stephan Gaillard, Amandine Ferrière, Pascal Roy, Emmanuel Jouanneau, Philippe Bertolino, Claire Bardel, Damien Sanlaville…

    Citation: Acta Neuropathologica Communications 2020 8:190

    Content type: Research

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  17. Mutations in the PTEN-induced kinase 1 (PINK1) and Parkin RBR E3 ubiquitin-protein ligase (PARKIN) genes are associated with familial forms of Parkinson’s disease (PD). PINK1, a protein kinase, and PARKIN, an ...

    Authors: Peter M. J. Quinn, Paula I. Moreira, António Francisco Ambrósio and C. Henrique Alves

    Citation: Acta Neuropathologica Communications 2020 8:189

    Content type: Review

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  18. Spinal muscular atrophy (SMA) is largely linked to deletion or mutation of the Survival motor neuron 1 (SMN1) gene located on chromosome 5q13. Type III (Kugelberg–Welander disease) is the mildest childhood form a...

    Authors: Catherine Elizabeth Pringle, Robert Nelson, Willie Miller, Rashmi Kothary and Jean Michaud

    Citation: Acta Neuropathologica Communications 2020 8:188

    Content type: Case report

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  19. The hexanucleotide repeat expansion in intron 1 of the C9orf72 gene causes amyotrophic lateral sclerosis (ALS) and frontotemporal dementia. In addition to the effects of the pathogenic expansion, a role of interm...

    Authors: Karri Kaivola, Samuli J. Salmi, Lilja Jansson, Jyrki Launes, Laura Hokkanen, Anna-Kaisa Niemi, Kari Majamaa, Jari Lahti, Johan G. Eriksson, Timo Strandberg, Hannu Laaksovirta and Pentti J. Tienari

    Citation: Acta Neuropathologica Communications 2020 8:187

    Content type: Research

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  20. A subset of glioblastomas (GBMs) harbors potentially druggable oncogenic FGFR3-TACC3 (F3T3) fusions. However, their associated molecular and clinical features are poorly understood. Here we analyze the frequency ...

    Authors: Douglas A. Mata, Jamal K. Benhamida, Andrew L. Lin, Chad M. Vanderbilt, Soo-Ryum Yang, Liliana B. Villafania, Donna C. Ferguson, Philip Jonsson, Alexandra M. Miller, Viviane Tabar, Cameron W. Brennan, Nelson S. Moss, Martin Sill, Ryma Benayed, Ingo K. Mellinghoff, Marc K. Rosenblum…

    Citation: Acta Neuropathologica Communications 2020 8:186

    Content type: Research

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  21. Abnormal synaptic formation and signaling is one of the key molecular features of autism spectrum disorders (ASD). Cortactin binding protein 2 (CTTNBP2), an ASD-linked gene, is known to regulate the subcellular d...

    Authors: Pu-Yun Shih, Bing-Yuan Hsieh, Ching-Yen Tsai, Chiu-An Lo, Brian E. Chen and Yi-Ping Hsueh

    Citation: Acta Neuropathologica Communications 2020 8:185

    Content type: Research

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  22. A C9orf72 repeat expansion is the most common genetic cause of frontotemporal dementia (FTD) and amyotrophic lateral sclerosis. One of the suggested pathomechanisms is toxicity from dipeptide repeat proteins (DPR...

    Authors: Annelies Quaegebeur, Idoia Glaria, Tammaryn Lashley and Adrian M. Isaacs

    Citation: Acta Neuropathologica Communications 2020 8:184

    Content type: Research

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  23. Recent discoveries have provided valuable insight into the genomic landscape of pediatric low-grade gliomas (LGGs) at diagnosis, facilitating molecularly targeted treatment. However, little is known about thei...

    Authors: Margot A. Lazow, Lindsey Hoffman, Austin Schafer, Diana S. Osorio, Daniel R. Boué, Sarah Rush, Erin Wright, Adam Lane, Mariko D. DeWire-Schottmiller, Teresa Smolarek, Jared Sipple, Heather Taggert, Jaime Reuss, Ralph Salloum, Trent R. Hummel, Peter de Blank…

    Citation: Acta Neuropathologica Communications 2020 8:182

    Content type: Research

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  24. Cerebral amyloid angiopathy (CAA), defined as the accumulation of amyloid-beta (Aβ) on the vascular wall, is a major pathology of Alzheimer’s disease (AD) and has been thought to be caused by the failure of Aβ...

    Authors: Shin Heun Kim, Ji Hoon Ahn, Hyunwoo Yang, Peter Lee, Gou Young Koh and Yong Jeong

    Citation: Acta Neuropathologica Communications 2020 8:181

    Content type: Research

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  25. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Bradley R. Groveman, Christina D. Orrù, Andrew G. Hughson, Lynne D. Raymond, Gianluigi Zanusso, Bernardino Ghetti, Katrina J. Campbell, Jiri Safar, Douglas Galasko and Byron Caughey

    Citation: Acta Neuropathologica Communications 2020 8:180

    Content type: Correction

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    The original article was published in Acta Neuropathologica Communications 2018 6:7

  26. The clinical implications of plasmatic cell-free and tumor DNA (cfDNA and ctDNA) are challenging in glioblastoma. This prospective study included 52 consecutive newly diagnosed glioblastoma (n = 49) or gliosar...

    Authors: Maxime Fontanilles, Florent Marguet, Ludivine Beaussire, Nicolas Magne, Louis-Ferdinand Pépin, Cristina Alexandru, Isabelle Tennevet, Chantal Hanzen, Olivier Langlois, Fabrice Jardin, Annie Laquerrière, Nasrin Sarafan-Vasseur, Fréderic Di Fiore and Florian Clatot

    Citation: Acta Neuropathologica Communications 2020 8:179

    Content type: Research

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  27. Authors: Arnault Tauziède-Espariat, Gaëlle Pierron, Aurore Siegfried, Delphine Guillemot, Emmanuelle Uro-Coste, Yvan Nicaise, David Castel, Isabelle Catalaa, Delphine Larrieu-Ciron, Patrick Chaynes, Amaury de Barros, Julien Nicolau, Albane Gareton, Emmanuèle Lechapt, Fabrice Chrétien, Franck Bourdeaut…

    Citation: Acta Neuropathologica Communications 2020 8:178

    Content type: Letter to the Editor

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  28. The most common genetic cause of amyotrophic lateral sclerosis (ALS) is a GGGGCC (G4C2) hexanucleotide repeat expansions in first intron of the C9orf72 gene. The accumulation of repetitive RNA sequences can media...

    Authors: Nandini Ramesh, Elizabeth L. Daley, Amanda M. Gleixner, Jacob R. Mann, Sukhleen Kour, Darilang Mawrie, Eric N. Anderson, Julia Kofler, Christopher J. Donnelly, Evangelos Kiskinis and Udai Bhan Pandey

    Citation: Acta Neuropathologica Communications 2020 8:177

    Content type: Research

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  29. TAR DNA-binding protein of 43 kDa (TDP-43) is a major component of intracellular aggregates formed in brains of the patients with frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS...

    Authors: Ryohei Watanabe, Shinji Higashi, Takashi Nonaka, Ito Kawakami, Kenichi Oshima, Kazuhiro Niizato, Haruhiko Akiyama, Mari Yoshida, Masato Hasegawa and Tetsuaki Arai

    Citation: Acta Neuropathologica Communications 2020 8:176

    Content type: Research

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  30. We recently demonstrated that when mice are exposed to chronic mild hypoxia (CMH, 8% O2), blood vessels in the spinal cord show transient vascular leak that is associated with clustering and activation of microgl...

    Authors: Sebok K. Halder and Richard Milner

    Citation: Acta Neuropathologica Communications 2020 8:175

    Content type: Research

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  31. The lectin pathway (LP) of complement activation is believed to contribute to brain inflammation. The study aims to identify the key components of the LP contributing to TBI outcome as possible novel pharmacol...

    Authors: D. Mercurio, M. Oggioni, S. Fumagalli, N. J. Lynch, S. Roscher, D. Minuta, C. Perego, S. Ippati, R. Wallis, W. J. Schwaeble and M.-G. De Simoni

    Citation: Acta Neuropathologica Communications 2020 8:174

    Content type: Research

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  32. Ependymoma is the third most common brain tumor in children, with well-described molecular characterization but poorly understood underlying germline risk factors. To investigate whether genetic predisposition...

    Authors: Chenan Zhang, Quinn T. Ostrom, Eleanor C. Semmes, Vijay Ramaswamy, Helen M. Hansen, Libby Morimoto, Adam J. de Smith, Melike Pekmezci, Zalman Vaksman, Hakon Hakonarson, Sharon J. Diskin, Catherine Metayer, Michael D. Taylor, Joseph L. Wiemels, Melissa L. Bondy and Kyle M. Walsh

    Citation: Acta Neuropathologica Communications 2020 8:173

    Content type: Research

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  33. Missense variants ABI3_rs616338-T and PLCG2_rs72824905-G were previously associated with elevated or reduced risk of Alzheimer’s disease (AD), respectively. Despite reports of associations with other neurodegener...

    Authors: Samantha L. Strickland, Hélène Morel, Christian Prusinski, Mariet Allen, Tulsi A. Patel, Minerva M. Carrasquillo, Olivia J. Conway, Sarah J. Lincoln, Joseph S. Reddy, Thuy Nguyen, Kimberly G. Malphrus, Alexandra I. Soto, Ronald L. Walton, Julia E. Crook, Melissa E. Murray, Bradley F. Boeve…

    Citation: Acta Neuropathologica Communications 2020 8:172

    Content type: Research

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  34. Genomic studies of high-grade/progressive meningiomas have reported a heterogeneous mutation spectrum, identifying few recurrently mutated genes. Most studies have been underpowered to detect genomic subclasse...

    Authors: Erik A. Williams, Sandro Santagata, Hiroaki Wakimoto, Ganesh M. Shankar, Fred G. Barker II, Radwa Sharaf, Abhinav Reddy, Phoebe Spear, Brian M. Alexander, Jeffrey S. Ross, Priscilla K. Brastianos, Daniel P. Cahill, Shakti H. Ramkissoon and Tareq A. Juratli

    Citation: Acta Neuropathologica Communications 2020 8:171

    Content type: Research

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  35. In Alzheimer’s disease (AD), microglia are affected by disease processes, but may also drive pathogenesis. AD pathology-associated microglial populations have been identified with single-cell RNA-Seq, but have...

    Authors: Molly E. V. Swanson, Emma L. Scotter, Leon C. D. Smyth, Helen C. Murray, Brigid Ryan, Clinton Turner, Richard L. M. Faull, Mike Dragunow and Maurice A. Curtis

    Citation: Acta Neuropathologica Communications 2020 8:170

    Content type: Research

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  36. IDH-mutant astrocytomas have a more indolent natural history and better prognosis than their IDH-wild type counterparts, but are still graded according to schemes developed prior to the recognition of this typ...

    Authors: Daniel F. Marker and Thomas M. Pearce

    Citation: Acta Neuropathologica Communications 2020 8:169

    Content type: Research

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  37. Recent studies suggest that misfolded tau molecules can be released, and taken up by adjacent neurons, propagating proteopathic seeds across neural systems. Yet critical to understanding whether tau propagatio...

    Authors: Marta Perez-Rando, Simon Dujardin, Rachel E. Bennett, Caitlin Commins, Tara Nibhanupudy and Bradley T. Hyman

    Citation: Acta Neuropathologica Communications 2020 8:168

    Content type: Research

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  38. X-linked myotubular myopathy (XLMTM) is a life-threatening skeletal muscle disease caused by mutations in the MTM1 gene. XLMTM fibres display a population of nuclei mispositioned in the centre. In the present stu...

    Authors: Jacob A. Ross, Hichem Tasfaout, Yotam Levy, Jennifer Morgan, Belinda S. Cowling, Jocelyn Laporte, Edmar Zanoteli, Norma B. Romero, Dawn A. Lowe, Heinz Jungbluth, Michael W. Lawlor, David L. Mack and Julien Ochala

    Citation: Acta Neuropathologica Communications 2020 8:167

    Content type: Research

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  39. Repeated exposure to mild TBI (mTBI) has been linked to an increased risk of Alzheimer’s disease (AD), chronic traumatic encephalopathy (CTE) and other neurodegenerative diseases. Some pathological features ty...

    Authors: Alexander Morin, Benoit Mouzon, Scott Ferguson, Daniel Paris, Mackenzie Browning, William Stewart, Mike Mullan and Fiona Crawford

    Citation: Acta Neuropathologica Communications 2020 8:166

    Content type: Research

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  40. Autosomal dominant mutations in LITAF are responsible for the rare demyelinating peripheral neuropathy, Charcot–Marie–Tooth disease type 1C (CMT1C). The LITAF protein is expressed in many human cell types and we ...

    Authors: James R. Edgar, Anita K. Ho, Matilde Laurá, Rita Horvath, Mary M. Reilly, J. Paul Luzio and Rhys C. Roberts

    Citation: Acta Neuropathologica Communications 2020 8:165

    Content type: Research

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  41. Missense mutations in UBQLN2 cause X-linked dominant inheritance of amyotrophic lateral sclerosis with frontotemporal dementia (ALS/FTD). UBQLN2 belongs to a family of four highly homologous proteins expressed in...

    Authors: Shaoteng Wang, Micaela Tatman and Mervyn J. Monteiro

    Citation: Acta Neuropathologica Communications 2020 8:164

    Content type: Research

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  42. Heterozygous, loss-of-function mutations in the granulin gene (GRN) encoding progranulin (PGRN) are a common cause of frontotemporal dementia (FTD). Homozygous GRN mutations cause neuronal ceroid lipofuscinosis-1...

    Authors: Meixiang Huang, Erica Modeste, Eric Dammer, Paola Merino, Georgia Taylor, Duc M. Duong, Qiudong Deng, Christopher J. Holler, Marla Gearing, Dennis Dickson, Nicholas T. Seyfried and Thomas Kukar

    Citation: Acta Neuropathologica Communications 2020 8:163

    Content type: Research

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  43. Mitochondrial health is important in ageing and dysfunctional oxidative phosphorylation (OXPHOS) accelerates ageing and influences neurodegeneration. Mitochondrial DNA (mtDNA) codes for vital OXPHOS subunits a...

    Authors: Rebecca R. Valentino, Nikoleta Tamvaka, Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto-Beasley, Ronald L. Walton, Shunsuke Koga, Ryan J. Uitti, Zbigniew K. Wszolek, Dennis W. Dickson and Owen A. Ross

    Citation: Acta Neuropathologica Communications 2020 8:162

    Content type: Research

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  44. Increasing evidence suggests that propagation of the motor neuron disease amyotrophic lateral sclerosis (ALS) involves the pathogenic aggregation of disease-associated proteins that spread in a prion-like mann...

    Authors: Manuela Lehmann, Matthew Marklund, Anna-Lena Bolender, Elaheh E. Bidhendi, Per Zetterström, Peter M. Andersen, Thomas Brännström, Stefan L. Marklund, Jonathan D. Gilthorpe and Ulrika Nordström

    Citation: Acta Neuropathologica Communications 2020 8:161

    Content type: Research

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  45. In the clinical diagnosis of dementia with Lewy bodies, distinction from Alzheimer’s disease is suboptimal and complicated by shared genetic risk factors and frequent co-pathology. In the present study we test...

    Authors: Barbara E. Spencer, Robin G. Jennings, Chun C. Fan and James B. Brewer

    Citation: Acta Neuropathologica Communications 2020 8:160

    Content type: Research

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  46. Microglia are the primary immune-competent cells of the central nervous system (CNS) and sense both pathogen- and host-derived factors through several receptor systems including the Toll-like receptor (TLR) fa...

    Authors: Masataka Ifuku, Lukas Hinkelmann, Leonard D. Kuhrt, Ibrahim E. Efe, Victor Kumbol, Alice Buonfiglioli, Christina Krüger, Philipp Jordan, Marcus Fulde, Mami Noda, Helmut Kettenmann and Seija Lehnardt

    Citation: Acta Neuropathologica Communications 2020 8:159

    Content type: Research

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  47. A large intronic hexanucleotide repeat expansion (GGGGCC) within the C9orf72 (C9orf72-SMCR8 Complex Subunit) locus is the most prevalent genetic cause of both Frontotemporal Dementia (FTD) and Motor Neuron Dis...

    Authors: Ryan J. H. West, Joanne L. Sharpe, André Voelzmann, Anna L. Munro, Ines Hahn, Richard A. Baines and Stuart Pickering-Brown

    Citation: Acta Neuropathologica Communications 2020 8:158

    Content type: Research

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  48. Melanoma brain metastases (MBM) portend a grim prognosis and can occur in up to 40% of melanoma patients. Genomic characterization of brain metastases has been previously carried out to identify potential muta...

    Authors: Erin M. Taylor, Stephanie D. Byrum, Jacob L. Edmondson, Christopher P. Wardell, Brittany G. Griffin, Sara C. Shalin, Murat Gokden, Issam Makhoul, Alan J. Tackett and Analiz Rodriguez

    Citation: Acta Neuropathologica Communications 2020 8:157

    Content type: Case report

    Published on:

  49. In tauopathies, phosphorylation, acetylation, cleavage and other modifications of tau drive intracellular generation of diverse forms of toxic tau aggregates and associated seeding activity, which have been im...

    Authors: Tao Yang, Harry Liu, Kevin C. Tran, Albert Leng, Stephen M. Massa and Frank M. Longo

    Citation: Acta Neuropathologica Communications 2020 8:156

    Content type: Research

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