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  1. Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a genetic paradigm of small vessel disease (SVD) caused by NOTCH3 mutations that stereotypically lead to the...

    Authors: Rikesh M. Rajani, Julien Ratelade, Valérie Domenga-Denier, Yoshiki Hase, Hannu Kalimo, Raj N. Kalaria and Anne Joutel

    Citation: Acta Neuropathologica Communications 2019 7:187

    Content type: Research

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  2. Numerous clinical studies have established the debilitating neurocognitive side effects of chemotherapy in the treatment of breast cancer, often referred as chemobrain. We hypothesize that cognitive impairment...

    Authors: Barrett D. Allen, Lauren A. Apodaca, Amber R. Syage, Mineh Markarian, Al Anoud D. Baddour, Harutyun Minasyan, Leila Alikhani, Celine Lu, Brian L. West, Erich Giedzinski, Janet E. Baulch and Munjal M. Acharya

    Citation: Acta Neuropathologica Communications 2019 7:186

    Content type: Research

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  3. Many biology-based precision drugs are available that neutralize aberrant molecular pathways in cancer. Molecular heterogeneity and the lack of reliable companion diagnostic biomarkers for many drugs makes tar...

    Authors: Krissie Lenting, Corina N. A. M. van den Heuvel, Anne van Ewijk, Duaa ElMelik, Remco de Boer, Elizabeth Tindall, Ge Wei, Benno Kusters, Maarten te Dorsthorst, Mark ter Laan, Martijn A. Huynen and William P. Leenders

    Citation: Acta Neuropathologica Communications 2019 7:185

    Content type: Research

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  4. Targeting alpha-synuclein (α-syn) as a therapeutic strategy for Parkinson’s disease (PD) has been intensively pursued largely due to its well-recognized pathogenic role. Since its discovery as the first famili...

    Authors: Rebecca Z. Fan, Min Guo, Shouqing Luo, Mei Cui and Kim Tieu

    Citation: Acta Neuropathologica Communications 2019 7:184

    Content type: Research

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  5. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most common cause of familial Parkinson’s disease (PD). While the clinical presentation of LRRK2 mutation carriers is similar to that of idiopathic PD (iP...

    Authors: Michael X. Henderson, Medha Sengupta, John Q. Trojanowski and Virginia M. Y. Lee

    Citation: Acta Neuropathologica Communications 2019 7:183

    Content type: Research

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  6. Mild traumatic brain injury (mTBI) leads to diverse symptoms including mood disorders, cognitive decline, and behavioral changes. In some individuals, these symptoms become chronic and persist in the long-term...

    Authors: Nicole Schwab, Karl Grenier and Lili-Naz Hazrati

    Citation: Acta Neuropathologica Communications 2019 7:182

    Content type: Research

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  7. Risk stratification of children with ependymomas of the posterior fossa in current therapeutic protocols is mainly based on clinical criteria. We aimed to identify independent outcome predictors for this disea...

    Authors: Stephanie T. Jünger, Martin Mynarek, Inken Wohlers, Evelyn Dörner, Anja zur Mühlen, Natalia Velez-Char, Katja von Hoff, Stefan Rutkowski, Monika Warmuth-Metz, Rolf-Dieter Kortmann, Beate Timmermann, Sven Rahmann, Ludger Klein-Hitpass, Andre O. von Bueren and Torsten Pietsch

    Citation: Acta Neuropathologica Communications 2019 7:181

    Content type: Research

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  8. Alzheimer’s disease (AD) is the most common form of dementia in the elderly. According to the amyloid hypothesis, the accumulation and deposition of amyloid-beta (Aβ) peptides play a key role in AD. Soluble Aβ...

    Authors: Inès R. H. Ben-Nejma, Aneta J. Keliris, Jasmijn Daans, Peter Ponsaerts, Marleen Verhoye, Annemie Van der Linden and Georgios A. Keliris

    Citation: Acta Neuropathologica Communications 2019 7:180

    Content type: Research

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  9. In the original version of this article [1], there was 1 error in the affiliation of the European Institute of Oncology (affiliation 3). In this correction article the updated affiliation is shown for clarific...

    Authors: Ashirwad Merve, Xinyu Zhang, Nicola Pomella, Serena Acquati, Joerg D. Hoeck, Anaelle Dumas, Gabriel Rosser, Yichen Li, Jennie Jeyapalan, Silvia Vicenzi, Qianhai Fan, Zeng Jie Yang, Arianna Sabò, Denise Sheer, Axel Behrens and Silvia Marino

    Citation: Acta Neuropathologica Communications 2019 7:179

    Content type: Correction

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    The original article was published in Acta Neuropathologica Communications 2019 7:95

  10. Alzheimer’s disease (AD)-related amyloid β-peptide (Aβ) pathology in the form of amyloid plaques and cerebral amyloid angiopathy (CAA) spreads in its topographical distribution, increases in quantity, and unde...

    Authors: Dietmar Rudolf Thal, Alicja Ronisz, Thomas Tousseyn, Ajeet Rijal Upadhaya, Karthikeyan Balakrishnan, Rik Vandenberghe, Mathieu Vandenbulcke, Christine A. F. von Arnim, Markus Otto, Thomas G. Beach, Johan Lilja, Kerstin Heurling, Aruna Chakrabarty, Azzam Ismail, Christopher Buckley, Adrian P. L. Smith…

    Citation: Acta Neuropathologica Communications 2019 7:178

    Content type: Research

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  11. Intraneuronal insoluble inclusions made of Tau protein are neuropathological hallmarks of Alzheimer Disease (AD). Cleavage of Tau by legumain (LGMN) has been proposed to be crucial for aggregation of Tau into ...

    Authors: Kerstin Schlegel, Khader Awwad, Roland G. Heym, David Holzinger, Annika Doell, Stefan Barghorn, Thomas R. Jahn, Corinna Klein, Yulia Mordashova, Michael Schulz and Laura Gasparini

    Citation: Acta Neuropathologica Communications 2019 7:177

    Content type: Research

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  12. Authors: Arnault Tauziède-Espariat, Mélanie Pagès, Alexandre Roux, Aurore Siegfried, Emmanuelle Uro-Coste, Yvan Nicaise, Annick Sevely, Marion Gambart, Sergio Boetto, Martin Dupuy, Pomone Richard, Romain Perbet, Matthieu Vinchon, Sabine Caron, Felipe Andreiuolo, Albane Gareton…

    Citation: Acta Neuropathologica Communications 2019 7:176

    Content type: Letter to the Editor

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  13. All cancer cells need to maintain functional telomeres to sustain continuous cell division and proliferation. In human diffuse gliomas, functional telomeres are maintained due either to reactivation of telomer...

    Authors: Nathalie Grandin, Bruno Pereira, Camille Cohen, Pauline Billard, Caroline Dehais, Catherine Carpentier, Ahmed Idbaih, Franck Bielle, François Ducray, Dominique Figarella-Branger, Jean-Yves Delattre, Marc Sanson, Patrick Lomonte, Delphine Poncet, Pierre Verrelle and Michel Charbonneau

    Citation: Acta Neuropathologica Communications 2019 7:175

    Content type: Research

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  14. Microglial function is highly dependent on cell motility, with baseline motility required for homeostatic surveillance activity and directed motility to migrate towards a source of injury. Experimental evidenc...

    Authors: Diana K. Franco-Bocanegra, Bethany George, Laurie C. Lau, Clive Holmes, James A. R. Nicoll and Delphine Boche

    Citation: Acta Neuropathologica Communications 2019 7:174

    Content type: Research

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  15. Adolescent binge drinking represents a major public health challenge and can lead to persistent neurological and mental conditions, but the underlying pathogenic mechanisms remain poorly understood. Using a mo...

    Authors: James Rice, Laurence Coutellier, Jeffrey L. Weiner and Chen Gu

    Citation: Acta Neuropathologica Communications 2019 7:173

    Content type: Research

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  16. Non-tumoural cells within the tumour microenvironment (TME) influence tumour proliferation, invasiveness and angiogenesis. Little is known about TME in pituitary neuroendocrine tumours (PitNETs). We aimed to c...

    Authors: Pedro Marques, Sayka Barry, Eivind Carlsen, David Collier, Amy Ronaldson, Sherine Awad, Neil Dorward, Joan Grieve, Nigel Mendoza, Samiul Muquit, Ashley B. Grossman, Frances Balkwill and Márta Korbonits

    Citation: Acta Neuropathologica Communications 2019 7:172

    Content type: Research

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  17. The detection of amyloid beta deposits and neurofibrillary tangles, both hallmarks of Alzheimer’s disease (AD), is key to understanding the mechanisms underlying these pathologies. Luminescent conjugated oligo...

    Authors: Maria Calvo-Rodriguez, Steven S. Hou, Austin C. Snyder, Simon Dujardin, Hamid Shirani, K. Peter R. Nilsson and Brian J. Bacskai

    Citation: Acta Neuropathologica Communications 2019 7:171

    Content type: Research

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  18. Although it has been suggested that the co-expression of multiple pathological proteins associated with neurodegeneration may act synergistically to induce more widespread neuropathology, experimental evidence...

    Authors: Alexander J. Moszczynski, Madeline Harvey, Niveen Fulcher, Cleusa de Oliveira, Patrick McCunn, Neil Donison, Robert Bartha, Susanne Schmid, Michael J. Strong and Kathryn Volkening

    Citation: Acta Neuropathologica Communications 2019 7:170

    Content type: Research

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  19. To date, the development of disease-modifying therapies for Alzheimer’s disease (AD) has largely focused on the removal of amyloid beta Aβ fragments from the CNS. Proteomic profiling of patient fluids may help...

    Authors: Christopher D. Whelan, Niklas Mattsson, Michael W. Nagle, Swetha Vijayaraghavan, Craig Hyde, Shorena Janelidze, Erik Stomrud, Julie Lee, Lori Fitz, Tarek A. Samad, Gayathri Ramaswamy, Richard A. Margolin, Anders Malarstig and Oskar Hansson

    Citation: Acta Neuropathologica Communications 2019 7:169

    Content type: Research

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  20. The family of juvenile xanthogranuloma family neoplasms (JXG) with ERK-pathway mutations are now classified within the “L” (Langerhans) group, which includes Langerhans cell histiocytosis (LCH) and Erdheim Che...

    Authors: J. Picarsic, T. Pysher, H. Zhou, M. Fluchel, T. Pettit, M. Whitehead, L. F. Surrey, B. Harding, G. Goldstein, Y. Fellig, M. Weintraub, B. C. Mobley, P. M. Sharples, M. L. Sulis, E. L. Diamond, R. Jaffe…

    Citation: Acta Neuropathologica Communications 2019 7:168

    Content type: Research

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  21. Co-occurrence of multiple neuropathologic changes is a common phenomenon, most prominently seen in Alzheimer’s disease (AD) and Parkinson’s disease (PD), complicating clinical diagnosis and patient management....

    Authors: Amanda N. Sacino, Stefan Prokop, Meggen A. Walsh, Jennifer Adamson, S. H. Subramony, Amy Krans, Peter K. Todd, Benoit I. Giasson and Anthony T. Yachnis

    Citation: Acta Neuropathologica Communications 2019 7:158

    Content type: Case report

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  22. CGG repeat expansions in FMR1 cause the neurodegenerative disorder Fragile X-associated Tremor/Ataxia Syndrome (FXTAS). Ubiquitinated neuronal intranuclear inclusions (NIIs) are the neuropathological hallmark of ...

    Authors: Amy Krans, Geena Skariah, Yuan Zhang, Bryana Bayly and Peter K. Todd

    Citation: Acta Neuropathologica Communications 2019 7:152

    Content type: Research

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  23. Glycogen storage disorder type III (GSDIII), or debranching enzyme (GDE) deficiency, is a rare metabolic disorder characterized by variable liver, cardiac, and skeletal muscle involvement. GSDIII manifests wit...

    Authors: Pascal Laforêt, Michio Inoue, Evelyne Goillot, Claire Lefeuvre, Umut Cagin, Nathalie Streichenberger, Sarah Leonard-Louis, Guy Brochier, Angeline Madelaine, Clemence Labasse, Carola Hedberg-Oldfors, Thomas Krag, Louisa Jauze, Julien Fabregue, Philippe Labrune, Jose Milisenda…

    Citation: Acta Neuropathologica Communications 2019 7:167

    Content type: Research

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  24. Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative condition that primarily affects the motor system and shares many features with frontotemporal dementia (FTD). Evidence suggests that ALS is a ‘...

    Authors: Matthew A. White, Ziqiang Lin, Eugene Kim, Christopher M. Henstridge, Emiliano Pena Altamira, Camille K. Hunt, Ella Burchill, Isobel Callaghan, Andrea Loreto, Heledd Brown-Wright, Richard Mead, Camilla Simmons, Diana Cash, Michael P. Coleman and Jemeen Sreedharan

    Citation: Acta Neuropathologica Communications 2019 7:166

    Content type: Research

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  25. Amyotrophic lateral sclerosis (ALS) is characterized pathologically by the occurrence of phosphorylated TDP-43 (pTDP-43)-immunoreactive neuronal and glial inclusions in the central nervous system. Recent studi...

    Authors: Fumiaki Mori, Mari Tada, Tomoya Kon, Yasuo Miki, Kunikazu Tanji, Hidekachi Kurotaki, Masahiko Tomiyama, Tomohiko Ishihara, Osamu Onodera, Akiyoshi Kakita and Koichi Wakabayashi

    Citation: Acta Neuropathologica Communications 2019 7:165

    Content type: Research

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  26. Chronic traumatic encephalopathy (CTE) is a tauopathy associated to repetitive head trauma. There are no validated in vivo biomarkers of CTE and a definite diagnosis can only be made at autopsy. Recent studies...

    Authors: Marta Marquié, Cinthya Agüero, Ana C. Amaral, Alberto Villarejo-Galende, Prianca Ramanan, Michael Siao Tick Chong, Nil Sáez-Calveras, Rachel E. Bennett, Eline E. Verwer, Sally Ji Who Kim, Maeva Dhaynaut, Victor E. Alvarez, Keith A. Johnson, Ann C. McKee, Matthew P. Frosch and Teresa Gómez-Isla

    Citation: Acta Neuropathologica Communications 2019 7:164

    Content type: Research

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  27. In this multi-institutional study we compiled a retrospective cohort of 86 posterior fossa tumors having received the diagnosis of cerebellar glioblastoma (cGBM). All tumors were reviewed histologically and su...

    Authors: Annekathrin Reinhardt, Damian Stichel, Daniel Schrimpf, Christian Koelsche, Annika K. Wefers, Azadeh Ebrahimi, Philipp Sievers, Kristin Huang, M. Belén Casalini, Francisco Fernández-Klett, Abigail Suwala, Michael Weller, Dorothee Gramatzki, Joerg Felsberg, Guido Reifenberger, Albert Becker…

    Citation: Acta Neuropathologica Communications 2019 7:163

    Content type: Research

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  28. For the proper organization of the six-layered mammalian neocortex it is required that neurons migrate radially from their place of birth towards their designated destination. The molecular machinery underlyin...

    Authors: Lena Will, Sybren Portegies, Jasper van Schelt, Merel van Luyk, Dick Jaarsma and Casper C. Hoogenraad

    Citation: Acta Neuropathologica Communications 2019 7:162

    Content type: Research

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  29. A hexanucleotide repeat expansion in a noncoding region of C9orf72 is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). Reduction of select or total C9orf72 t...

    Authors: Shangxi Xiao, Paul M. McKeever, Agnes Lau and Janice Robertson

    Citation: Acta Neuropathologica Communications 2019 7:161

    Content type: Research

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  30. Aggregation of alpha-synuclein (α-SYN) is the pathological hallmark of several diseases named synucleinopathies, including Parkinson’s disease (PD), which is the most common neurodegenerative motor disorder. A...

    Authors: Teresa Torre-Muruzabal, Jens Devoght, Chris Van den Haute, Bert Brône, Anke Van der Perren and Veerle Baekelandt

    Citation: Acta Neuropathologica Communications 2019 7:160

    Content type: Research

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  31. Tau aggregation is a hallmark feature in a subset of patients with frontotemporal dementia (FTD). Early and selective loss of von Economo neurons (VENs) and fork cells within the frontoinsular (FI) and anterio...

    Authors: Li-Chun Lin, Alissa L. Nana, Mackenzie Hepker, Ji-Hye Lee Hwang, Stephanie E. Gaus, Salvatore Spina, Celica G. Cosme, Li Gan, Lea T. Grinberg, Daniel H. Geschwind, Giovanni Coppola, Howard J. Rosen, Bruce L. Miller and William W. Seeley

    Citation: Acta Neuropathologica Communications 2019 7:159

    Content type: Research

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  32. In the original publication of this article [1], Fig. 10 contained two panels “C” as panel “F” was accidentally omitted. The incorrect (Fig. 1) and correct (Fig. 2) versions are published in this correction ar...

    Authors: Praveena Manogaran, Marijana Samardzija, Anaïs Nura Schad, Carla Andrea Wicki, Christine Walker-Egger, Markus Rudin, Christian Grimm and Sven Schippling

    Citation: Acta Neuropathologica Communications 2019 7:157

    Content type: Correction

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    The original article was published in Acta Neuropathologica Communications 2019 7:116

  33. The detection of IDH mutations in patients with diffusely infiltrating malignant astrocytomas resulted in substantial modifications in the concept of WHO classification of these tumors. An important underlying...

    Authors: Arne Christians, Antonia Adel-Horowski, Rouzbeh Banan, Ulrich Lehmann, Stephan Bartels, Felix Behling, Alonso Barrantes-Freer, Christine Stadelmann, Veit Rohde, Florian Stockhammer and Christian Hartmann

    Citation: Acta Neuropathologica Communications 2019 7:156

    Content type: Research

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  34. Glioblastoma cell ability to adapt their functioning to microenvironment changes is a source of the extensive intra-tumor heterogeneity characteristic of this devastating malignant brain tumor. A systemic view...

    Authors: Mirca S. Saurty-Seerunghen, Léa Bellenger, Elias A. El-Habr, Virgile Delaunay, Delphine Garnier, Hervé Chneiweiss, Christophe Antoniewski, Ghislaine Morvan-Dubois and Marie-Pierre Junier

    Citation: Acta Neuropathologica Communications 2019 7:155

    Content type: Research

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  35. Spinal muscular atrophy (SMA) is an inherited neuromuscular disorder, which causes dysfunction/loss of lower motor neurons and muscle weakness as well as atrophy. While SMA is primarily considered as a motor n...

    Authors: Wiebke A. Rehorst, Maximilian P. Thelen, Hendrik Nolte, Clara Türk, Sebahattin Cirak, Jonathan M. Peterson, G. William Wong, Brunhilde Wirth, Marcus Krüger, Dominic Winter and Min Jeong Kye

    Citation: Acta Neuropathologica Communications 2019 7:154

    Content type: Research

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  36. Major depressive disorder (MDD) is one of the most frequent psychiatric illnesses, leading to reduced quality of life, ability to work and sociability, thus ranking among the major causes of disability and mor...

    Authors: Hélène Party, Cléo Dujarrier, Marie Hébert, Sophie Lenoir, Sara Martinez de Lizarrondo, Raphaël Delépée, Claudine Fauchon, Marie-Christine Bouton, Pauline Obiang, Olivier Godefroy, Etienne Save, Laurent Lecardeur, Joëlle Chabry, Denis Vivien and Véronique Agin

    Citation: Acta Neuropathologica Communications 2019 7:153

    Content type: Research

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  37. Cardiovascular disorders, like atherosclerosis and hypertension, are increasingly known to be associated with vascular cognitive impairment (VCI). In particular, intracranial atherosclerosis is one of the main...

    Authors: Dorien M. A. Hermkens, Olga C. G. Stam, Nienke M. de Wit, Ruud D. Fontijn, Aldo Jongejan, Perry D. Moerland, Claire Mackaaij, Ingeborg S. E. Waas, Mat J. A. P. Daemen and Helga E. de Vries

    Citation: Acta Neuropathologica Communications 2019 7:151

    Content type: Research

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  38. The majority of the clinico-pathological variability observed in patients harboring a repeat expansion in the C9orf72-SMCR8 complex subunit (C9orf72) remains unexplained. This expansion, which represents the most...

    Authors: Dennis W. Dickson, Matthew C. Baker, Jazmyne L. Jackson, Mariely DeJesus-Hernandez, NiCole A. Finch, Shulan Tian, Michael G. Heckman, Cyril Pottier, Tania F. Gendron, Melissa E. Murray, Yingxue Ren, Joseph S. Reddy, Neill R. Graff-Radford, Bradley F. Boeve, Ronald C. Petersen, David S. Knopman…

    Citation: Acta Neuropathologica Communications 2019 7:150

    Content type: Research

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  39. Multifunctional signal transducer and activator of transcription (STAT) proteins play important roles in cancer. Here, we have shown that STAT6 is epigenetically silenced in some cases of malignant glioblastom...

    Authors: Soo Jung Park, Hyunmi Kim, Se Hyuk Kim, Eun-hye Joe and Ilo Jou

    Citation: Acta Neuropathologica Communications 2019 7:149

    Content type: Research

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  40. Synucleinopathies [Parkinson’s disease (PD), dementia with Lewy bodies (DLB) and multiple system atrophy (MSA)] share filamentous α-synuclein assemblies in nerve cells and glial cells. We compared the abilitie...

    Authors: Isabelle Lavenir, Daniela Passarella, Masami Masuda-Suzukake, Annabelle Curry, Janice L. Holton, Bernardino Ghetti and Michel Goedert

    Citation: Acta Neuropathologica Communications 2019 7:148

    Content type: Research

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  41. The coordinated movement of organisms relies on efficient nerve-muscle communication at the neuromuscular junction. After peripheral nerve injury or neurodegeneration, motor neurons and Schwann cells increase ...

    Authors: Viviana Pérez, Francisca Bermedo-Garcia, Diego Zelada, Felipe A. Court, Miguel Ángel Pérez, Marco Fuenzalida, Johanna Ábrigo, Claudio Cabello-Verrugio, Guillermo Moya-Alvarado, Juan Carlos Tapia, Vicente Valenzuela, Claudio Hetz, Francisca C. Bronfman and Juan Pablo Henríquez

    Citation: Acta Neuropathologica Communications 2019 7:147

    Content type: Research

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  42. Perfusing fixatives through the cerebrovascular system is the gold standard approach in animals to prepare brain tissue for spatial biomolecular profiling, circuit tracing, and ultrastructural studies such as ...

    Authors: Whitney C. McFadden, Hadley Walsh, Felix Richter, Céline Soudant, Clare H. Bryce, Patrick R. Hof, Mary Fowkes, John F. Crary and Andrew T. McKenzie

    Citation: Acta Neuropathologica Communications 2019 7:146

    Content type: Review

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  43. Alzheimer’s disease is characterized by cognitive alterations, cerebral atrophy and neuropathological lesions including neuronal loss, accumulation of misfolded and aggregated β-amyloid peptides (Aβ) and tau p...

    Authors: Charlotte Gary, Suzanne Lam, Anne-Sophie Hérard, James E. Koch, Fanny Petit, Pauline Gipchtein, Stephen J. Sawiak, Raphaëlle Caillierez, Sabiha Eddarkaoui, Morvane Colin, Fabienne Aujard, Jean-Philippe Deslys, Emmanuel Brouillet, Luc Buée, Emmanuel E. Comoy, Fabien Pifferi…

    Citation: Acta Neuropathologica Communications 2019 7:126

    Content type: Research

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  44. Over recent years, human autoantibodies targeting myelin oligodendrocyte glycoprotein (MOG Ab) have been associated with monophasic and relapsing central nervous system demyelination involving the optic nerves...

    Authors: Fiona Tea, Joseph A. Lopez, Sudarshini Ramanathan, Vera Merheb, Fiona X. Z. Lee, Alicia Zou, Deepti Pilli, Ellis Patrick, Anneke van der Walt, Mastura Monif, Esther M. Tantsis, Eppie M. Yiu, Steve Vucic, Andrew P. D. Henderson, Anthony Fok, Clare L. Fraser…

    Citation: Acta Neuropathologica Communications 2019 7:145

    Content type: Research

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  45. Electron microscopy (EM) provides the necessary resolution to visualize the finer structures of nervous tissue morphology, which is important to understand healthy and pathological conditions in the brain. How...

    Authors: Mariella Sele, Stefan Wernitznig, Saška Lipovšek, Snježana Radulović, Johannes Haybaeck, Anna Maria Birkl-Toeglhofer, Christina Wodlej, Florian Kleinegger, Stephan Sygulla, Marlene Leoni, Stefan Ropele and Gerd Leitinger

    Citation: Acta Neuropathologica Communications 2019 7:144

    Content type: Methodology article

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  46. Fragile X-associated tremor/ataxia syndrome (FXTAS) is a neurodegenerative disorder associated with a premutation repeat expansion (55–200 CGG repeats) in the 5′ noncoding region of the FMR1 gene. Solitary intran...

    Authors: Lisa Ma, Anthony W. Herren, Glenda Espinal, Jamie Randol, Bridget McLaughlin, Veronica Martinez-Cerdeño, Isaac N. Pessah, Randi J. Hagerman and Paul J. Hagerman

    Citation: Acta Neuropathologica Communications 2019 7:143

    Content type: Research

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  47. The protein α-synuclein (αsyn) forms pathologic aggregates in a number of neurodegenerative diseases including Lewy body dementia (LBD) and Parkinson’s disease (PD). It is unclear why diseases such as LBD may ...

    Authors: Zachary A. Sorrentino, Marshall S. Goodwin, Cara J. Riffe, Jess-Karan S. Dhillon, Yuxing Xia, Kimberly-Marie Gorion, Niran Vijayaraghavan, Karen N. McFarland, Lawrence I. Golbe, Anthony T. Yachnis and Benoit I. Giasson

    Citation: Acta Neuropathologica Communications 2019 7:142

    Content type: Research

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  48. Neuropathological follow-up of patients with Alzheimer’s disease (AD) who participated in the first clinical trial of Amyloid-β 42 (Aβ42) immunization (AN1792, Elan Pharmaceuticals) has shown that immunization...

    Authors: Lieke Jäkel, Delphine Boche, James A. R. Nicoll and Marcel M. Verbeek

    Citation: Acta Neuropathologica Communications 2019 7:141

    Content type: Research

    Published on:

  49. Intraventricular meningiomas (IVMs) account for less than 5% of all intracranial meningiomas; hence their molecular phenotype remains unknown. In this study, we were interested whether genetic alterations in I...

    Authors: Gerhard Jungwirth, Rolf Warta, Christopher Beynon, Felix Sahm, Andreas von Deimling, Andreas Unterberg, Christel Herold-Mende and Christine Jungk

    Citation: Acta Neuropathologica Communications 2019 7:140

    Content type: Research

    Published on:

  50. The presence of Alternative lengthening of telomeres (ALT) and/or ATRX loss, as well as the role of other telomere abnormalities, have not been formally studied across the spectrum of NF1-associated solid tumo...

    Authors: Fausto J. Rodriguez, Mindy K. Graham, Jacqueline A. Brosnan-Cashman, John R. Barber, Christine Davis, M. Adelita Vizcaino, Doreen N. Palsgrove, Caterina Giannini, Melike Pekmezci, Sonika Dahiya, Murat Gokden, Michael Noë, Laura D. Wood, Christine A. Pratilas, Carol D. Morris, Allan Belzberg…

    Citation: Acta Neuropathologica Communications 2019 7:139

    Content type: Research

    Published on:

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