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  1. Prion diseases are neurodegenerative disorders with long asymptomatic incubation periods, followed by a rapid progression of cognitive and functional decline culminating in death. The complexity of intercellul...

    Authors: Jessy A. Slota, Babu V. Sajesh, Kathy F. Frost, Sarah J. Medina and Stephanie A. Booth
    Citation: Acta Neuropathologica Communications 2022 10:161
  2. We report the case of a 22-year-old woman presenting with an acute onset of dizziness, gait dysbalance and blurred vision. Magnetic resonance imaging included 3 Tesla and 7 Tesla imaging and revealed a T2-hype...

    Authors: Simon Hametner, Sara Silvaieh, Majda Thurnher, Assunta Dal-Bianco, Hakan Cetin, Markus Ponleitner, Karin Zebenholzer, Berthold Pemp, Siegfried Trattnig, Karl Rössler, Thomas Berger, Hans Lassmann, Johannes A. Hainfellner and Gabriel Bsteh
    Citation: Acta Neuropathologica Communications 2022 10:160
  3. A growing body of evidence supports the presence of a population of cells in glioblastoma (GBM) with a stem cell-like phenotype which shares certain biological markers with adult neural stem cells, including e...

    Authors: Nelli S. Lakis, Alexander S. Brodsky, Galina Karashchuk, Amanda J. Audesse, Dongfang Yang, Ashlee Sturtevant, Kara Lombardo, Ian Y. Wong, Ashley E. Webb and Douglas C. Anthony
    Citation: Acta Neuropathologica Communications 2022 10:159
  4. Neurodegenerative disorders are characterized by phenotypic changes and hallmark proteopathies. Quantifying these in archival human brain tissues remains indispensable for validating animal models and understa...

    Authors: Kausalia Vijayaragavan, Bryan J. Cannon, Dmitry Tebaykin, Marc Bossé, Alex Baranski, J. P. Oliveria, Syed A. Bukhari, Dunja Mrdjen, M. Ryan Corces, Erin F. McCaffrey, Noah F. Greenwald, Yari Sigal, Diana Marquez, Zumana Khair, Trevor Bruce, Mako Goldston…
    Citation: Acta Neuropathologica Communications 2022 10:158
  5. Tauopathies are a category of neurodegenerative diseases characterized by the presence of abnormal tau protein-containing neurofibrillary tangles (NFTs). NFTs are universally observed in aging, occurring with ...

    Authors: Gabriel A. Marx, Daniel G. Koenigsberg, Andrew T. McKenzie, Justin Kauffman, Russell W. Hanson, Kristen Whitney, Maxim Signaevsky, Marcel Prastawa, Megan A. Iida, Charles L. White III, Jamie M. Walker, Timothy E. Richardson, John Koll, Gerardo Fernandez, Jack Zeineh, Carlos Cordon-Cardo…
    Citation: Acta Neuropathologica Communications 2022 10:157
  6. Increasing evidence suggests synaptic dysfunction is a central and possibly triggering factor in Amyotrophic Lateral Sclerosis (ALS). Despite this, we still know very little about the molecular profile of an A...

    Authors: Zsofia I. Laszlo, Nicole Hindley, Anna Sanchez Avila, Rachel A. Kline, Samantha L. Eaton, Douglas J. Lamont, Colin Smith, Tara L. Spires-Jones, Thomas M. Wishart and Christopher M. Henstridge
    Citation: Acta Neuropathologica Communications 2022 10:156
  7. Pneumococcal meningitis is associated with dysregulation of the coagulation cascade. Previously, we detected upregulation of cerebral plasminogen activator inhibitor-2 (PAI-2) mRNA expression during pneumococc...

    Authors: Nina C. Teske, Joo-Yeon Engelen-Lee, Susanne Dyckhoff-Shen, Hans-Walter Pfister, Matthias Klein, Diederik van de Beek, Carsten K. Kirschning, Uwe Koedel and Matthijs C. Brouwer
    Citation: Acta Neuropathologica Communications 2022 10:155
  8. Myasthenia gravis (MG) is an autoantibody-mediated autoimmune disorder of the neuromuscular junction. A small subset of patients (<10%) with MG, have autoantibodies targeting muscle-specific tyrosine kinase (M...

    Authors: Miriam L. Fichtner, Kenneth B. Hoehn, Easton E. Ford, Marina Mane-Damas, Sangwook Oh, Patrick Waters, Aimee S. Payne, Melissa L. Smith, Corey T. Watson, Mario Losen, Pilar Martinez-Martinez, Richard J. Nowak, Steven H. Kleinstein and Kevin C. O’Connor
    Citation: Acta Neuropathologica Communications 2022 10:154
  9. Protein misfolding is a prominent pathological hallmark of neurodegenerative disorders, including Alzheimer’s disease (AD). Studies have shown that the diversity of β sheet-rich protein deposits (such as amylo...

    Authors: Anastasiia A. Stepanchuk, Megan L. Morgan, Jeffrey T. Joseph and Peter K. Stys
    Citation: Acta Neuropathologica Communications 2022 10:153
  10. Glioblastoma multiforme (GBM) is a primary brain tumor with poor prognosis. The U.S. food and drug administration approved the use of the anti-VEGF antibody bevacizumab in recurrent GBM. However, resistance to...

    Authors: Ahmad Joshkon, Emeline Tabouret, Wael Traboulsi, Richard Bachelier, Stéphanie Simoncini, Sandrine Roffino, Carine Jiguet-Jiglaire, Bassam Badran, Benjamin Guillet, Alexandrine Foucault-Bertaud, Aurelie S. Leroyer, Françoise Dignat-George, Olivier Chinot, Hussein Fayyad-Kazan, Nathalie Bardin and Marcel Blot-Chabaud
    Citation: Acta Neuropathologica Communications 2022 10:151
  11. Diffuse intrinsic pontine glioma (DIPG) is an aggressive incurable brainstem tumor that targets young children. Complete resection is not possible, and chemotherapy and radiotherapy are currently only palliati...

    Authors: Guisheng Zhao, Patrick Newbury, Yukitomo Ishi, Eugene Chekalin, Billy Zeng, Benjamin S. Glicksberg, Anita Wen, Shreya Paithankar, Takahiro Sasaki, Amreena Suri, Javad Nazarian, Michael E. Pacold, Daniel J. Brat, Theodore Nicolaides, Bin Chen and Rintaro Hashizume
    Citation: Acta Neuropathologica Communications 2022 10:150
  12. The pathophysiology of epilepsy underlies a complex network dysfunction between neurons and glia, the molecular cell type-specific contributions of which remain poorly defined in the human disease. In this stu...

    Authors: Balagopal Pai, Jessica Tome-Garcia, Wan Sze Cheng, German Nudelman, Kristin G. Beaumont, Saadi Ghatan, Fedor Panov, Elodia Caballero, Kwadwo Sarpong, Lara Marcuse, Jiyeoun Yoo, Yan Jiang, Anne Schaefer, Schahram Akbarian, Robert Sebra, Dalila Pinto…
    Citation: Acta Neuropathologica Communications 2022 10:149

    The Correction to this article has been published in Acta Neuropathologica Communications 2022 10:171

  13. Frontotemporal dementia (FTD) is caused by frontotemporal lobar degeneration (FTLD), characterized mainly by inclusions of Tau (FTLD-Tau) or TAR DNA binding43 (FTLD-TDP) proteins. Plasma biomarkers are strongl...

    Authors: R. Babapour Mofrad, M. del Campo, C. F. W. Peeters, L. H. H. Meeter, H. Seelaar, M. Koel-Simmelink, I. H. G. B. Ramakers, H. A. M. Middelkoop, P. P. De Deyn, J. A. H. R. Claassen, J. C. van Swieten, C. Bridel, J. J. M. Hoozemans, P. Scheltens, W. M. van der Flier, Y. A. L. Pijnenburg…
    Citation: Acta Neuropathologica Communications 2022 10:148
  14. Chemical and pharmaceutical exposures have been associated with the development of Gulf War Illness (GWI), but how these factors interact with the pathophysiology of traumatic brain injury (TBI) remains an are...

    Authors: Scott Ferguson, Robyn McCartan, Mackenzie Browning, Coral Hahn-Townsend, Arissa Gratkowski, Alexander Morin, Laila Abdullah, Ghania Ait-Ghezala, Joseph Ojo, Kimberly Sullivan, Michael Mullan, Fiona Crawford and Benoit Mouzon
    Citation: Acta Neuropathologica Communications 2022 10:147
  15. Relapsing remitting multiple sclerosis (MS) is an inflammatory demyelinating disorder of the central nervous system that in many cases leads to progressive MS, a neurodegenerative disease. Progressive MS is un...

    Authors: Michael S. LaCroix, Hilda Mirbaha, Ping Shang, Stephanie Zandee, Chan Foong, Alexandre Prat, Charles L. White III, Olaf Stuve and Marc I. Diamond
    Citation: Acta Neuropathologica Communications 2022 10:146
  16. Amyloid beta (Aβ) deposits in the retina of the Alzheimer’s disease (AD) eye may provide a useful diagnostic biomarker for AD. This study focused on the relationship of Aβ with macroglia and microglia, as thes...

    Authors: Qinyuan Alis Xu, Pierre Boerkoel, Veronica Hirsch-Reinshagen, Ian R. Mackenzie, Ging-Yuek Robin Hsiung, Geoffrey Charm, Elliott F. To, Alice Q. Liu, Katerina Schwab, Kailun Jiang, Marinko Sarunic, Mirza Faisal Beg, Wellington Pham, Jing Cui, Eleanor To, Sieun Lee…
    Citation: Acta Neuropathologica Communications 2022 10:145
  17. Regulatory T cells (Tregs) play a neuroprotective role by suppressing microglia and macrophage-mediated inflammation and modulating adaptive immune reactions. We previously documented that Treg immunomodulator...

    Authors: Alireza Faridar, Matthew Vasquez, Aaron D. Thome, Zheng Yin, Hui Xuan, Jing Hong Wang, Shixiang Wen, Xuping Li, Jason R. Thonhoff, Weihua Zhao, Hong Zhao, David R. Beers, Stephen T. C. Wong, Joseph C. Masdeu and Stanley H. Appel
    Citation: Acta Neuropathologica Communications 2022 10:144
  18. Gliomas are the most common central nervous tumors in children and adolescents. However, spinal cord low-grade gliomas (sLGGs) are rare, with scarce information on tumor genomics and epigenomics. To define the...

    Authors: Adela Misove, Ales Vicha, Petr Broz, Katerina Vanova, David Sumerauer, Lucie Stolova, Lucie Sramkova, Miroslav Koblizek, Josef Zamecnik, Martin Kyncl, Zuzana Holubova, Petr Liby, Jakub Taborsky, Vladimir Benes III, Ivana Pernikova, David T. W. Jones…
    Citation: Acta Neuropathologica Communications 2022 10:143

    The Correction to this article has been published in Acta Neuropathologica Communications 2022 10:162

  19. Pathogenic variants in the NDUFV1 gene, which codes for complex I of the mitochondrial respiratory chain, have been associated with a variety of clinical phenotypes, including a progressive cavitating leukoenceph...

    Authors: Nicole Becker, Aditi Sharma, Matthew Gosse, Brooke Kubat and Kyle S. Conway
    Citation: Acta Neuropathologica Communications 2022 10:142
  20. Authors: Sterre C. M. de Boer, Lauren Woolley, Merel O. Mol, Maria Serpente, Lianne M. Reus, Rick van Minkelen, Joke F. A. van Vugt, Federica Sorrentino, Jan H. Veldink, Harro Seelaar, Daniela Galimberti, Fred van Ruissen, Simon Mead, Ekaterina Rogaeva, Yolande A. L. Pijnenburg and Sven J. van der Lee
    Citation: Acta Neuropathologica Communications 2022 10:141

    The Letter to the Editor to this article has been published in Acta Neuropathologica Communications 2022 10:173

    The original article was published in Acta Neuropathologica Communications 2020 8:187

  21. Axonal swellings (AS) are one of the neuropathological hallmark of axonal injury in several disorders from trauma to neurodegeneration. Current evidence proposes a role of perturbed Ca2+ homeostasis in AS formati...

    Authors: Victorio M. Pozo Devoto, Valentina Lacovich, Monica Feole, Pratiksha Bhat, Jaroslav Chovan, Maria Čarna, Isaac G. Onyango, Neda Dragišić, Martina Sűsserová, Martin E. Barrios-Llerena and Gorazd B. Stokin
    Citation: Acta Neuropathologica Communications 2022 10:140
  22. Age-related cognitive impairment is multifactorial, with numerous underlying and frequently co-morbid pathological correlates. Amyloid beta (Aβ) plays a major role in Alzheimer’s type age-related cognitive imp...

    Authors: Andrew T. McKenzie, Gabriel A. Marx, Daniel Koenigsberg, Mary Sawyer, Megan A. Iida, Jamie M. Walker, Timothy E. Richardson, Gabriele Campanella, Johannes Attems, Ann C. McKee, Thor D. Stein, Thomas J. Fuchs, Charles L. White III, Kurt Farrell and John F. Crary
    Citation: Acta Neuropathologica Communications 2022 10:131
  23. Corticotroph macroadenomas are rare but difficult to manage intracranial neoplasms. Mutations in the two Cushing’s disease mutational hotspots USP8 and USP48 are less frequent in corticotroph macroadenomas and in...

    Authors: Luis Gustavo Perez-Rivas, Julia Simon, Adriana Albani, Sicheng Tang, Sigrun Roeber, Guillaume Assié, Timo Deutschbein, Martin Fassnacht, Monica R. Gadelha, Ad R. Hermus, Günter K. Stalla, Maria A. Tichomirowa, Roman Rotermund, Jörg Flitsch, Michael Buchfelder, Isabella Nasi-Kordhishti…
    Citation: Acta Neuropathologica Communications 2022 10:139
  24. Non-functioning pituitary tumours (NF-PitNETs) are common intracranial benign neoplasms that can exhibit aggressive behaviour by invading neighbouring structures and, in some cases, have multiple recurrences. ...

    Authors: Ashutosh Rai, Soujanya D. Yelamanchi, Bishan D. Radotra, Sunil K. Gupta, Kanchan K. Mukherjee, Manjul Tripathi, Rajesh Chhabra, Chirag K. Ahuja, Narendra Kumar, Akhilesh Pandey, Márta Korbonits, Pinaki Dutta and Carles Gaston-Massuet
    Citation: Acta Neuropathologica Communications 2022 10:138
  25. Posterior fossa group A ependymomas (EPN_PFA) are characterized by a loss of H3 K27 trimethylation due to either EZHIP overexpression or H3 p.K27M mutation, similar to H3 K27-altered diffuse midline gliomas (DMG)...

    Authors: Cassandra Mariet, David Castel, Jacques Grill, Raphaël Saffroy, Volodia Dangouloff-Ros, Nathalie Boddaert, Francisco Llamas-Guttierrez, Céline Chappé, Stéphanie Puget, Lauren Hasty, Fabrice Chrétien, Alice Métais, Pascale Varlet and Arnault Tauziède-Espariat
    Citation: Acta Neuropathologica Communications 2022 10:137
  26. Single cell RNA sequencing studies identified novel neurodegeneration-associated microglial (MGnD/DAM) subtypes activated around cerebral amyloid plaques. Micro-RNA (miR)-155 of the TREM2-APOE pathway was show...

    Authors: Haoshen Shi, Zhuoran Yin, Yosef Koronyo, Dieu-Trang Fuchs, Julia Sheyn, Miyah R. Davis, Jered W. Wilson, Milica A. Margeta, Kristen M. Pitts, Shawn Herron, Seiko Ikezu, Tsuneya Ikezu, Stuart L. Graham, Vivek K. Gupta, Keith L. Black, Mehdi Mirzaei…
    Citation: Acta Neuropathologica Communications 2022 10:136
  27. Increased protein citrullination (PC) and dysregulated protein arginine deiminase (PAD) activity have been observed in several neurodegenerative diseases. PC is a posttranslational modification catalyzed by th...

    Authors: Issa O. Yusuf, Tao Qiao, Sepideh Parsi, Ronak Tilvawala, Paul R. Thompson and Zuoshang Xu
    Citation: Acta Neuropathologica Communications 2022 10:135
  28. The molecular drivers of early sporadic Parkinson’s disease (PD) remain unclear, and the presence of widespread end stage pathology in late disease masks the distinction between primary or causal disease-speci...

    Authors: Christina E. Toomey, Wendy E. Heywood, James R. Evans, Joanne Lachica, Sarah N. Pressey, Sandrine C. Foti, Mesfer Al Shahrani, Karishma D’Sa, Iain P. Hargreaves, Simon Heales, Michael Orford, Claire Troakes, Johannes Attems, Ellen Gelpi, Miklos Palkovits, Tammaryn Lashley…
    Citation: Acta Neuropathologica Communications 2022 10:134
  29. The pathological hallmarks of Parkinson’s disease (PD) are α-synuclein (αSYN)-positive inclusions referred to as Lewy bodies and Lewy neurites, collectively referred to as Lewy-related pathology (LRP). LRP is ...

    Authors: Hiroaki Sekiya, Asato Tsuji, Yuki Hashimoto, Mariko Takata, Shunsuke Koga, Katsuya Nishida, Naonobu Futamura, Michi Kawamoto, Nobuo Kohara, Dennis W. Dickson, Hisatomo Kowa and Tatsushi Toda
    Citation: Acta Neuropathologica Communications 2022 10:133
  30. Propagation of tau pathology via the seeding of naive tau aggregation underlies the progression of Alzheimer’s disease (AD) and related tauopathies. Individuals with Down syndrome (DS) develop tau pathology at...

    Authors: Nana Jin, Jianlan Gu, Ruozhen Wu, Dandan Chu, Yunn Chyn Tung, Jerzy Wegiel, Thomas Wisniewski, Cheng-Xin Gong, Khalid Iqbal and Fei Liu
    Citation: Acta Neuropathologica Communications 2022 10:132
  31. Saccular intracranial aneurysm (sIA) rupture leads to subarachnoid haemorrhage and is preceded by chronic inflammation and atherosclerotic changes of the sIA wall. Increased lymphangiogenesis has been detected...

    Authors: Nora Huuska, Eliisa Netti, Satu Lehti, Petri T. Kovanen, Mika Niemelä and Riikka Tulamo
    Citation: Acta Neuropathologica Communications 2022 10:130
  32. Cerebellar dysfunction is commonly observed following traumatic brain injury (TBI). While direct impact to the cerebellum by TBI is rare, cerebellar pathology may be caused by indirect injury via cortico-cereb...

    Authors: Ilknur Özen, Hongcheng Mai, Alessandro De Maio, Karsten Ruscher, Georgios Michalettos, Fredrik Clausen, Michael Gottschalk, Saema Ansar, Sertan Arkan, Ali Erturk and Niklas Marklund
    Citation: Acta Neuropathologica Communications 2022 10:129
  33. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is associated with various neurological complications. Although the mechanism is not fully understood, several studies have shown that neu...

    Authors: Lisa Bauer, Melanie Rissmann, Feline F. W. Benavides, Lonneke Leijten, Peter van Run, Lineke Begeman, Edwin J. B. Veldhuis Kroeze, Bas Lendemeijer, Hilde Smeenk, Femke M. S. de Vrij, Steven A. Kushner, Marion P. G. Koopmans, Barry Rockx and Debby van Riel
    Citation: Acta Neuropathologica Communications 2022 10:124
  34. It has become evident that Alzheimer’s Disease (AD) is not only linked to its hallmark lesions—amyloid plaques and neurofibrillary tangles (NFTs)—but also to other co-occurring pathologies. This may lead to sy...

    Authors: Marta J. Koper, Sandra O. Tomé, Klara Gawor, Annelies Belet, Evelien Van Schoor, Jolien Schaeverbeke, Rik Vandenberghe, Mathieu Vandenbulcke, Estifanos Ghebremedhin, Markus Otto, Christine A. F. von Arnim, Sriram Balusu, Matthew B. Blaschko, Bart De Strooper and Dietmar Rudolf Thal
    Citation: Acta Neuropathologica Communications 2022 10:128
  35. α-Dystrobrevin (α-DB) is a major component of the dystrophin-associated protein complex (DAPC). Knockout (KO) of α-DB in the brain is associated with astrocytic abnormalities and loss of neuronal GABA receptor...

    Authors: Cheryl A. Hawkes, Christopher J. Heath, Matthew M. Sharp, Dariusz C. Górecki and Roxana O. Carare
    Citation: Acta Neuropathologica Communications 2022 10:127
  36. Glioblastoma (GBM) is the most common and most aggressive primary brain tumor in adults. Glioma stem like cells (GSC) represent the highest cellular hierarchy in GBM and have a determining role in tumor growth...

    Authors: Jiaxin Li, Fredrik Ek, Roger Olsson, Mattias Belting and Johan Bengzon
    Citation: Acta Neuropathologica Communications 2022 10:126
  37. Alzheimer´s disease (AD), the most common form of dementia in industrialized countries, severely targets the hippocampal formation in humans and mouse models of this condition. The adult hippocampus hosts the ...

    Authors: B. Márquez-Valadez, A. Rábano and M. Llorens-Martín
    Citation: Acta Neuropathologica Communications 2022 10:125
  38. Ependymoma is the second most common malignant brain tumor in children. The etiology is largely unknown and germline DNA sequencing studies focusing on childhood ependymoma are limited. We therefore performed ...

    Authors: Jon Foss-Skiftesvik, Ulrik Kristoffer Stoltze, Thomas van Overeem Hansen, Lise Barlebo Ahlborn, Erik Sørensen, Sisse Rye Ostrowski, Solvej Margrete Aldringer Kullegaard, Adrian Otamendi Laspiur, Linea Cecilie Melchior, David Scheie, Bjarne Winther Kristensen, Jane Skjøth-Rasmussen, Kjeld Schmiegelow, Karin Wadt and René Mathiasen
    Citation: Acta Neuropathologica Communications 2022 10:123
  39. Multiple neurotoxic proteinopathies co-exist within vulnerable neuronal populations in all major neurodegenerative diseases. Interactions between these pathologies may modulate disease progression, suggesting ...

    Authors: Benjamin G. Trist, Jennifer A. Fifita, Alison Hogan, Natalie Grima, Bradley Smith, Claire Troakes, Caroline Vance, Christopher Shaw, Safa Al-Sarraj, Ian P. Blair and Kay L. Double
    Citation: Acta Neuropathologica Communications 2022 10:122
  40. Axonal transport ensures long-range delivery of essential cargoes between proximal and distal compartments, and is needed for neuronal development, function, and survival. Deficits in axonal transport have bee...

    Authors: Andrew P. Tosolini, James N. Sleigh, Sunaina Surana, Elena R. Rhymes, Stephen D. Cahalan and Giampietro Schiavo
    Citation: Acta Neuropathologica Communications 2022 10:121
  41. A major obstacle to identifying improved treatments for pediatric low-grade brain tumors (gliomas) is the inability to reproducibly generate human xenografts. To surmount this barrier, we leveraged human induc...

    Authors: Corina Anastasaki, Jit Chatterjee, Olivia Cobb, Shilpa Sanapala, Suzanne M. Scheaffer, Amanda De Andrade Costa, Anna F. Wilson, Chloe M. Kernan, Ameera H. Zafar, Xia Ge, Joel R. Garbow, Fausto J. Rodriguez and David H. Gutmann
    Citation: Acta Neuropathologica Communications 2022 10:120
  42. Authors: Arnault Tauziède-Espariat, Aurore Siegfried, Emmanuelle Uro-Coste, Yvan Nicaise, David Castel, Annick Sevely, Marion Gambart, Sergio Boetto, Lauren Hasty, Alice Métais, Fabrice Chrétien, Joseph Benzakoun, Stéphanie Puget, Jacques Grill, Volodia Dangouloff-Ros, Nathalie Boddaert…
    Citation: Acta Neuropathologica Communications 2022 10:119
  43. Neuroinflammation is recognized as a key component of neurodegenerative disease. In glaucoma, a common neurodegenerative disease and the leading cause of irreversible blindness, the evidence for neuroinflammat...

    Authors: Carola Rutigliani, James R. Tribble, Anna Hagström, Emma Lardner, Gauti Jóhannesson, Gustav Stålhammar and Pete A. Williams
    Citation: Acta Neuropathologica Communications 2022 10:118
  44. Biallelic inactivation of NF2 represents the primary or sole oncogenic driver event in the vast majority of schwannomas. We report on a four-year-old female who underwent subtotal resection of a right medullar...

    Authors: Matthias A. Karajannis, Bryan K. Li, Mark M. Souweidane, Benjamin Liechty, JinJuan Yao, Jamal K. Benhamida, Tejus A. Bale and Marc K. Rosenblum
    Citation: Acta Neuropathologica Communications 2022 10:117
  45. Multiple studies have recognized the involvement of the complement cascade during Alzheimer’s disease pathogenesis. However, the specific role of C5a-C5aR1 signaling in the progression of this neurodegenerativ...

    Authors: Angela Gomez-Arboledas, Klebea Carvalho, Gabriela Balderrama-Gutierrez, Shu-Hui Chu, Heidi Yahan Liang, Nicole D. Schartz, Purnika Selvan, Tiffany J. Petrisko, Miranda A. Pan, Ali Mortazavi and Andrea J. Tenner
    Citation: Acta Neuropathologica Communications 2022 10:116
  46. Chromosomal instability (CIN) is a fundamental property of cancer and a key underlying mechanism of tumorigenesis and malignant progression, and has been documented in a wide variety of cancers, including colo...

    Authors: Timothy E. Richardson, Jamie M. Walker, Kalil G. Abdullah, Samuel K. McBrayer, Mariano S. Viapiano, Zarmeen M. Mussa, Nadejda M. Tsankova, Matija Snuderl and Kimmo J. Hatanpaa
    Citation: Acta Neuropathologica Communications 2022 10:115
  47. The methionine (M)—valine (V) polymorphic codon 129 of the prion protein gene (PRNP) plays a central role in both susceptibility and phenotypic expression of sporadic Creutzfeldt-Jakob diseases (sCJD). Experiment...

    Authors: Ellen Gelpi, Simone Baiardi, Carlos Nos, Sofia Dellavalle, Iban Aldecoa, Raquel Ruiz-Garcia, Lourdes Ispierto, Domingo Escudero, Virgina Casado, Elena Barranco, Anuncia Boltes, Laura Molina-Porcel, Nuria Bargalló, Marcello Rossi, Angela Mammana, Dorina Tiple…
    Citation: Acta Neuropathologica Communications 2022 10:114
  48. Alzheimer’s disease (AD) is a progressive and irreversible neurodegenerative disease characterized by the accumulation of aggregated amyloid beta (Aβ) and hyperphosphorylated tau along with a slow decline in c...

    Authors: Eva Baerends, Katia Soud, Jonas Folke, Anna-Kathrine Pedersen, Simon Henmar, Lisa Konrad, Matthew D. Lycas, Yuki Mori, Bente Pakkenberg, David P. D. Woldbye, Oksana Dmytriyeva and Stanislava Pankratova
    Citation: Acta Neuropathologica Communications 2022 10:113
  49. Alzheimer's disease (AD) is characterized by intracerebral accumulations of extracellular amyloid-β (Aβ) plaques and intracellular tau pathology that spread in the brain. Three types of tau lesions occur in th...

    Authors: Suzanne Lam, Anne-Sophie Hérard, Susana Boluda, Fanny Petit, Sabiha Eddarkaoui, Karine Cambon, Jean-Luc Picq, Luc Buée, Charles Duyckaerts, Stéphane Haïk and Marc Dhenain
    Citation: Acta Neuropathologica Communications 2022 10:112

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