Skip to main content

Articles

Page 1 of 22

  1. Mitochondrial health is important in ageing and dysfunctional oxidative phosphorylation (OXPHOS) accelerates ageing and influences neurodegeneration. Mitochondrial DNA (mtDNA) codes for vital OXPHOS subunits a...

    Authors: Rebecca R. Valentino, Nikoleta Tamvaka, Michael G. Heckman, Patrick W. Johnson, Alexandra I. Soto-Beasley, Ronald L. Walton, Shunsuke Koga, Ryan J. Uitti, Zbigniew K. Wszolek, Dennis W. Dickson and Owen A. Ross

    Citation: Acta Neuropathologica Communications 2020 8:162

    Content type: Research

    Published on:

  2. Increasing evidence suggests that propagation of the motor neuron disease amyotrophic lateral sclerosis (ALS) involves the pathogenic aggregation of disease-associated proteins that spread in a prion-like mann...

    Authors: Manuela Lehmann, Matthew Marklund, Anna-Lena Bolender, Elaheh E. Bidhendi, Per Zetterström, Peter M. Andersen, Thomas Brännström, Stefan L. Marklund, Jonathan D. Gilthorpe and Ulrika Nordström

    Citation: Acta Neuropathologica Communications 2020 8:161

    Content type: Research

    Published on:

  3. In the clinical diagnosis of dementia with Lewy bodies, distinction from Alzheimer’s disease is suboptimal and complicated by shared genetic risk factors and frequent co-pathology. In the present study we test...

    Authors: Barbara E. Spencer, Robin G. Jennings, Chun C. Fan and James B. Brewer

    Citation: Acta Neuropathologica Communications 2020 8:160

    Content type: Research

    Published on:

  4. Microglia are the primary immune-competent cells of the central nervous system (CNS) and sense both pathogen- and host-derived factors through several receptor systems including the Toll-like receptor (TLR) fa...

    Authors: Masataka Ifuku, Lukas Hinkelmann, Leonard D. Kuhrt, Ibrahim E. Efe, Victor Kumbol, Alice Buonfiglioli, Christina Krüger, Philipp Jordan, Marcus Fulde, Mami Noda, Helmut Kettenmann and Seija Lehnardt

    Citation: Acta Neuropathologica Communications 2020 8:159

    Content type: Research

    Published on:

  5. A large intronic hexanucleotide repeat expansion (GGGGCC) within the C9orf72 (C9orf72-SMCR8 Complex Subunit) locus is the most prevalent genetic cause of both Frontotemporal Dementia (FTD) and Motor Neuron Dis...

    Authors: Ryan J. H. West, Joanne L. Sharpe, André Voelzmann, Anna L. Munro, Ines Hahn, Richard A. Baines and Stuart Pickering-Brown

    Citation: Acta Neuropathologica Communications 2020 8:158

    Content type: Research

    Published on:

  6. Melanoma brain metastases (MBM) portend a grim prognosis and can occur in up to 40% of melanoma patients. Genomic characterization of brain metastases has been previously carried out to identify potential muta...

    Authors: Erin M. Taylor, Stephanie D. Byrum, Jacob L. Edmondson, Christopher P. Wardell, Brittany G. Griffin, Sara C. Shalin, Murat Gokden, Issam Makhoul, Alan J. Tackett and Analiz Rodriguez

    Citation: Acta Neuropathologica Communications 2020 8:157

    Content type: Case report

    Published on:

  7. In tauopathies, phosphorylation, acetylation, cleavage and other modifications of tau drive intracellular generation of diverse forms of toxic tau aggregates and associated seeding activity, which have been im...

    Authors: Tao Yang, Harry Liu, Kevin C. Tran, Albert Leng, Stephen M. Massa and Frank M. Longo

    Citation: Acta Neuropathologica Communications 2020 8:156

    Content type: Research

    Published on:

  8. Hexanucleotide repeat expansion of C9ORF72 is the most common genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia. Synergies between loss of C9ORF72 functions and gain of toxicities from th...

    Authors: Wan Yun Ho, Sheeja Navakkode, Fujia Liu, Tuck Wah Soong and Shuo-Chien Ling

    Citation: Acta Neuropathologica Communications 2020 8:155

    Content type: Letter to the Editor

    Published on:

  9. Filamin C (FLNc) is mainly expressed in striated muscle cells where it localizes to Z-discs, myotendinous junctions and intercalated discs. Recent studies have revealed numerous mutations in the FLNC gene causing...

    Authors: Julia Schuld, Zacharias Orfanos, Frédéric Chevessier, Britta Eggers, Lorena Heil, Julian Uszkoreit, Andreas Unger, Gregor Kirfel, Peter F. M. van der Ven, Katrin Marcus, Wolfgang A. Linke, Christoph S. Clemen, Rolf Schröder and Dieter O. Fürst

    Citation: Acta Neuropathologica Communications 2020 8:154

    Content type: Research

    Published on:

  10. In the brains of tauopathy patients, tau pathology coincides with the presence of granulovacuolar degeneration bodies (GVBs) both at the regional and cellular level. Recently, it was shown that intracellular t...

    Authors: Vera I. Wiersma, Jeroen J. M. Hoozemans and Wiep Scheper

    Citation: Acta Neuropathologica Communications 2020 8:153

    Content type: Review

    Published on:

  11. Blood-brain barrier (BBB) disruption is a common feature in neurodegenerative diseases. However, BBB integrity has not been assessed in spinocerebellar ataxias (SCAs) such as Machado-Joseph disease/SCA type 3 ...

    Authors: Diana Duarte Lobo, Rui Jorge Nobre, Catarina Oliveira Miranda, Dina Pereira, João Castelhano, José Sereno, Arnulf Koeppen, Miguel Castelo-Branco and Luís Pereira de Almeida

    Citation: Acta Neuropathologica Communications 2020 8:152

    Content type: Research

    Published on:

  12. The FGFR1 gene encoding fibroblast growth factor receptor 1 has emerged as a frequently altered oncogene in the pathogenesis of multiple low-grade neuroepithelial tumor (LGNET) subtypes including pilocytic astroc...

    Authors: Calixto-Hope G. Lucas, Rohit Gupta, Pamela Doo, Julieann C. Lee, Cathryn R. Cadwell, Biswarathan Ramani, Jeffrey W. Hofmann, Emily A. Sloan, Bette K. Kleinschmidt-DeMasters, Han S. Lee, Matthew D. Wood, Marjorie Grafe, Donald Born, Hannes Vogel, Shahriar Salamat, Diane Puccetti…

    Citation: Acta Neuropathologica Communications 2020 8:151

    Content type: Research

    Published on:

  13. It is necessary to develop an understanding of the specific mechanisms involved in alpha-synuclein aggregation and propagation to develop disease modifying therapies for age-related synucleinopathies, includin...

    Authors: Allison J. Schaser, Teresa L. Stackhouse, Leah J. Weston, Patrick C. Kerstein, Valerie R. Osterberg, Claudia S. López, Dennis W. Dickson, Kelvin C. Luk, Charles K. Meshul, Randall L. Woltjer and Vivek K. Unni

    Citation: Acta Neuropathologica Communications 2020 8:150

    Content type: Research

    Published on:

  14. Alzheimer’s disease (AD) neuropathologic change is characterized by amyloid plaques and neurofibrillary tangles (NFTs) that consist of aggregated amyloid beta (Abeta) and hyperphosphorylated tau proteins (p-ta...

    Authors: Kanta Horie, Nicolas R. Barthélemy, Nipun Mallipeddi, Yan Li, Erin E. Franklin, Richard J. Perrin, Randall J. Bateman and Chihiro Sato

    Citation: Acta Neuropathologica Communications 2020 8:149

    Content type: Research

    Published on:

  15. We describe an autopsied patient with familial parkinsonism and unclassified four repeat-tau (4R-tau) aggregation. She presented with bradykinesia, truncal dystonia, and mild amnesia at the age of 61 and then ...

    Authors: Masayoshi Nakano, Yuichi Riku, Kenya Nishioka, Masato Hasegawa, Yukihiko Washimi, Yutaka Arahata, Akinori Takeda, Kentaro Horibe, Akiko Yamaoka, Keisuke Suzuki, Masashi Tsujimoto, Yuanzhe Li, Hiroyo Yoshino, Nobutaka Hattori, Akio Akagi, Hiroaki Miyahara…

    Citation: Acta Neuropathologica Communications 2020 8:148

    Content type: Case report

    Published on:

  16. We document the neuropathologic findings of a 73-year old man who died from acute cerebellar hemorrhage in the context of relatively mild SARS-CoV2 infection. The patient developed sudden onset of headache, na...

    Authors: Osama Al-Dalahmah, Kiran T. Thakur, Anna S. Nordvig, Morgan L. Prust, William Roth, Angela Lignelli, Anne-Catrin Uhlemann, Emily Happy Miller, Shajo Kunnath-Velayudhan, Armando Del Portillo, Yang Liu, Gunnar Hargus, Andrew F. Teich, Richard A. Hickman, Kurenai Tanji, James E. Goldman…

    Citation: Acta Neuropathologica Communications 2020 8:147

    Content type: Case report

    Published on:

  17. NG2 is a type I transmembrane glycoprotein known as chondroitin sulfate proteoglycan 4 (CSPG4). In the healthy central nervous system, NG2 is exclusively expressed by oligodendrocyte progenitor cells and by va...

    Authors: Wenhui Huang, Xianshu Bai, Erika Meyer and Anja Scheller

    Citation: Acta Neuropathologica Communications 2020 8:146

    Content type: Research

    Published on:

  18. The catalytic activity of human Telomerase Reverse Transcriptase (TERT) compensates for the loss of telomere length, eroded during each cell cycle, to ensure a correct division of stem and germinal cells. In h...

    Authors: Tiziana Pierini, Carlotta Nardelli, Anair Graciela Lema Fernandez, Valentina Pierini, Fabrizia Pellanera, Valeria Nofrini, Paolo Gorello, Martina Moretti, Silvia Arniani, Giovanni Roti, Paolo Giovenali, Marco Lupattelli, Giulio Metro, Carmen Molica, Corrado Castrioto, Rodolfo Corinaldesi…

    Citation: Acta Neuropathologica Communications 2020 8:145

    Content type: Case report

    Published on:

  19. Both monogenic diseases and viral infections can manifest in a broad spectrum of clinical phenotypes that range from asymptomatic to lethal, suggesting that other factors modulate disease severity. Here, we ex...

    Authors: Sharon Melamed, Roy Avraham, Deborah E. Rothbard, Noam Erez, Tomer Israely, Ziv Klausner, Anthony H. Futerman, Nir Paran and Einat B. Vitner

    Citation: Acta Neuropathologica Communications 2020 8:144

    Content type: Research

    Published on:

  20. Molecular chaperones and co-chaperones, which are part of the protein quality control machinery, have been shown to regulate distinct aspects of Alzheimer’s Disease (AD) pathology in multiple ways. Notably, th...

    Authors: Rachel E. Lackie, Jose Marques-Lopes, Valeriy G. Ostapchenko, Sarah Good, Wing-Yiu Choy, Patricija van Oosten-Hawle, Stephen H. Pasternak, Vania F. Prado and Marco A. M. Prado

    Citation: Acta Neuropathologica Communications 2020 8:143

    Content type: Research

    Published on:

  21. Ovine congenital progressive muscular dystrophy (OCPMD) was first described in Merino sheep flocks in Queensland and Western Australia in the 1960s and 1970s. The most prominent feature of the disease is a dis...

    Authors: Joshua S. Clayton, Elyshia L. McNamara, Hayley Goullee, Stefan Conijn, Keren Muthsam, Gabrielle C. Musk, David Coote, James Kijas, Alison C. Testa, Rhonda L. Taylor, Amanda J. O’Hara, David Groth, Coen Ottenheijm, Gianina Ravenscroft, Nigel G. Laing and Kristen J. Nowak

    Citation: Acta Neuropathologica Communications 2020 8:142

    Content type: Research

    Published on:

  22. Down syndrome (DS) occurs with triplication of human chromosome 21 and is associated with deviations in cortical development evidenced by simplified gyral appearance and reduced cortical surface area. Radial g...

    Authors: Ana A. Baburamani, Regina T. Vontell, Alena Uus, Maximilian Pietsch, Prachi A. Patkee, Jo Wyatt-Ashmead, Evonne C. Chin-Smith, Veena G. Supramaniam, J. Donald Tournier, Maria Deprez and Mary A. Rutherford

    Citation: Acta Neuropathologica Communications 2020 8:141

    Content type: Research

    Published on:

  23. Despite the considerable progress made towards understanding ALS pathophysiology, several key features of ALS remain unexplained, from its aetiology to its epidemiological aspects. The glymphatic system, which...

    Authors: Koy Chong Ng Kee Kwong, Arpan R. Mehta, Maiken Nedergaard and Siddharthan Chandran

    Citation: Acta Neuropathologica Communications 2020 8:140

    Content type: Review

    Published on:

  24. We present a case of a 14-year old boy with tumor-associated refractory epilepsy. Positron emission tomography imaging demonstrated a region with heterogeneous high 11C-methionine uptake and a region with homogen...

    Authors: Kensuke Tateishi, Naoki Ikegaya, Naoko Udaka, Jo Sasame, Takahiro Hayashi, Yohei Miyake, Tetsuhiko Okabe, Ryogo Minamimoto, Hidetoshi Murata, Daisuke Utsunomiya, Shoji Yamanaka and Tetsuya Yamamoto

    Citation: Acta Neuropathologica Communications 2020 8:139

    Content type: Case report

    Published on:

  25. Amyotrophic lateral sclerosis (ALS) is an adult-onset, fatal neurodegenerative disease characterized by progressive loss of upper and lower motor neurons. While pathogenic mutations in the DNA/RNA-binding prot...

    Authors: Nandini Ramesh, Sukhleen Kour, Eric N. Anderson, Dhivyaa Rajasundaram and Udai Bhan Pandey

    Citation: Acta Neuropathologica Communications 2020 8:138

    Content type: Research

    Published on:

  26. Microangiopathy, including proliferation of small diameter capillaries, increasing vessel tortuosity, and increased capillary blockage by leukocytes, was previously observed in the aged rTg4510 mouse model. Si...

    Authors: Rachel E. Bennett, Miwei Hu, Analiese Fernandes, Marta Perez-Rando, Ashley Robbins, Tarun Kamath, Simon Dujardin and Bradley T. Hyman

    Citation: Acta Neuropathologica Communications 2020 8:137

    Content type: Research

    Published on:

  27. Myeloid cells contribute to inflammation and demyelination in the early stages of multiple sclerosis (MS), but it is still unclear to what extent these cells are involved in active lesion formation in progress...

    Authors: Chotima Böttcher, Marlijn van der Poel, Camila Fernández-Zapata, Stephan Schlickeiser, Julia K. H. Leman, Cheng-Chih Hsiao, Mark R. Mizee, Adelia, Maria C. J. Vincenten, Desiree Kunkel, Inge Huitinga, Jörg Hamann and Josef Priller

    Citation: Acta Neuropathologica Communications 2020 8:136

    Content type: Research

    Published on:

  28. Progressive multi-focal leukoencephalopathy (PML) is a potentially fatal encephalitis caused by JC polyomavirus (JCV). PML principally affects people with a compromised immune system, such as patients with mul...

    Authors: Lorna Hayden, Tiia Semenoff, Verena Schultz, Simon F. Merz, Katie J. Chapple, Moses Rodriguez, Arthur E. Warrington, Xiaohong Shi, Clive S. McKimmie, Julia M. Edgar, Katja Thümmler, Chris Linington and Marieke Pingen

    Citation: Acta Neuropathologica Communications 2020 8:135

    Content type: Research

    Published on:

  29. Alpha-synucleinopathies are a group of progressive neurodegenerative disorders, characterized by intracellular deposits of aggregated α-synuclein (αS). The clinical heterogeneity of these diseases is thought t...

    Authors: Gaye Tanriöver, Mehtap Bacioglu, Manuel Schweighauser, Jasmin Mahler, Bettina M. Wegenast-Braun, Angelos Skodras, Ulrike Obermüller, Melanie Barth, Deborah Kronenberg-Versteeg, K. Peter R. Nilsson, Derya R. Shimshek, Philipp J. Kahle, Yvonne S. Eisele and Mathias Jucker

    Citation: Acta Neuropathologica Communications 2020 8:133

    Content type: Research

    Published on:

  30. The transcription factor, p53, is critical for many important cellular functions involved in genome integrity, including cell cycle control, DNA damage response, and apoptosis. Disruption of p53 results in a w...

    Authors: Kathleen M. Farmer, Gaurav Ghag, Nicha Puangmalai, Mauro Montalbano, Nemil Bhatt and Rakez Kayed

    Citation: Acta Neuropathologica Communications 2020 8:132

    Content type: Research

    Published on:

  31. White matter hyperintensities (WMH) occur in association with dementia but the aetiology is unclear. Here we test the hypothesis that there is a combination of impaired elimination of interstitial fluid from t...

    Authors: Matthew MacGregor Sharp, Satoshi Saito, Abby Keable, Maureen Gatherer, Roxana Aldea, Nivedita Agarwal, Julie E. Simpson, Stephen B. Wharton, Roy O. Weller and Roxana O. Carare

    Citation: Acta Neuropathologica Communications 2020 8:131

    Content type: Research

    Published on:

  32. To comprehensively describe the pathological features of neurons in patients with ovarian teratomas and paraneoplastic anti-NMDAR encephalitis (anti-NMDARE), emphasizing on NMDA-receptor expression and infiltr...

    Authors: Xin-Yue Jiang, Song Lei, Le Zhang, Xu Liu, Min-Tao Lin, Ingmar Blumcke, Yue-Shan Piao, Dong Zhou and Jin-Mei Li

    Citation: Acta Neuropathologica Communications 2020 8:130

    Content type: Research

    Published on:

  33. Leukotrienes (LTs) contribute to the neuropathology of chronic neurodegenerative disorders including Alzheimer’s Disease (AD), where they mediate neuroinflammation and neuronal cell-death. In consequence, bloc...

    Authors: J. Michael, M. S. Unger, R. Poupardin, P. Schernthaner, H. Mrowetz, J. Attems and L. Aigner

    Citation: Acta Neuropathologica Communications 2020 8:129

    Content type: Research

    Published on:

  34. Intramedullary astrocytomas (IMAs) are rare tumors, and few studies specific to the molecular alterations of IMAs have been performed. Recently, KIAA1549-BRAF fusions and the H3F3A p.K27M mutation have been descr...

    Authors: Laetitia Lebrun, Barbara Meléndez, Oriane Blanchard, Nancy De Nève, Claude Van Campenhout, Julie Lelotte, Danielle Balériaux, Matteo Riva, Jacques Brotchi, Michaël Bruneau, Olivier De Witte, Christine Decaestecker, Nicky D’Haene and Isabelle Salmon

    Citation: Acta Neuropathologica Communications 2020 8:128

    Content type: Research

    Published on:

  35. Sandhoff disease (SD) is a lysosomal storage disease, caused by loss of β-hexosaminidase (HEX) activity resulting in the accumulation of ganglioside GM2. There are shared features between SD and Parkinson’s di...

    Authors: Oeystein R. Brekk, Joanna A. Korecka, Cecile C. Crapart, Mylene Huebecker, Zachary K. MacBain, Sara Ann Rosenthal, Miguel Sena-Esteves, David A. Priestman, Frances M. Platt, Ole Isacson and Penelope J. Hallett

    Citation: Acta Neuropathologica Communications 2020 8:127

    Content type: Research

    Published on:

  36. With evidence supporting the prion-like spreading of extracellular tau as a mechanism for the initiation and progression of Alzheimer’s disease (AD), immunotherapy has emerged as a potential disease-modifying ...

    Authors: Francesca Vitale, Jasmin Ortolan, Bruce T. Volpe, Philippe Marambaud, Luca Giliberto and Cristina d’Abramo

    Citation: Acta Neuropathologica Communications 2020 8:126

    Content type: Research

    Published on:

  37. Juvenile dermatomyositis (JDM) can be classified into clinical serological subgroups by distinct myositis-specific antibodies (MSAs). It is incompletely understood whether different MSAs are associated with di...

    Authors: Mailan Nguyen, Vy Do, Paul C. Yell, Chanhee Jo, Jie Liu, Dennis K. Burns, Tracey Wright and Chunyu Cai

    Citation: Acta Neuropathologica Communications 2020 8:125

    Content type: Research

    Published on:

  38. Recent updates in the classification of central nervous system (CNS) tumors have increased the need for molecular testing. Assessment of multiple alterations in parallel, complex combinations of gene sequence ...

    Authors: Julia Lorenz, Tanja Rothhammer-Hampl, Saida Zoubaa, Elisabeth Bumes, Tobias Pukrop, Oliver Kölbl, Selim Corbacioglu, Nils O. Schmidt, Martin Proescholdt, Peter Hau and Markus J. Riemenschneider

    Citation: Acta Neuropathologica Communications 2020 8:124

    Content type: Research

    Published on:

  39. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Jennifer Ngolab, Ivy Trinh, Edward Rockenstein, Michael Mante, Jazmin Florio, Margarita Trejo, Deborah Masliah, Anthony Adame, Eliezer Masliah and Robert A. Rissman

    Citation: Acta Neuropathologica Communications 2020 8:123

    Content type: Correction

    Published on:

    The original article was published in Acta Neuropathologica Communications 2017 5:46

  40. An intronic hexanucleotide repeat expansion in C9ORF72 causes familial and sporadic amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). This repeat is thought to elicit toxicity through RNA med...

    Authors: Fang He, Brittany N. Flores, Amy Krans, Michelle Frazer, Sam Natla, Sarjina Niraula, Olamide Adefioye, Sami J. Barmada and Peter K. Todd

    Citation: Acta Neuropathologica Communications 2020 8:122

    Content type: Research

    Published on:

  41. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Dietmar Rudolf Thal, Alicja Ronisz, Thomas Tousseyn, Ajeet Rijal Upadhaya, Karthikeyan Balakrishnan, Rik Vandenberghe, Mathieu Vandenbulcke, Christine A. F. von Arnim, Markus Otto, Thomas G. Beach, Johan Lilja, Kerstin Heurling, Aruna Chakrabarty, Azzam Ismail, Christopher Buckley, Adrian P. L. Smith…

    Citation: Acta Neuropathologica Communications 2020 8:121

    Content type: Correction

    Published on:

    The original article was published in Acta Neuropathologica Communications 2019 7:178

  42. Multiple system atrophy (MSA) is pathologically characterized by the presence of fibrillar α-synuclein-immunoreactive inclusions in oligodendrocytes. Although the myelinating process of oligodendrocytes can be...

    Authors: Seiji Kaji, Takakuni Maki, Jun Ueda, Tomoyuki Ishimoto, Yutaka Inoue, Ken Yasuda, Masanori Sawamura, Rie Hikawa, Takashi Ayaki, Hodaka Yamakado and Ryosuke Takahashi

    Citation: Acta Neuropathologica Communications 2020 8:120

    Content type: Research

    Published on:

  43. It was recently revealed that gut microbiota promote amyloid-beta (Aβ) burden in mouse models of Alzheimer’s disease (AD). However, the underlying mechanisms when using either germ-free (GF) housing conditions...

    Authors: Charlotte Mezö, Nikolaos Dokalis, Omar Mossad, Ori Staszewski, Jana Neuber, Bahtiyar Yilmaz, Daniel Schnepf, Mercedes Gomez de Agüero, Stephanie C. Ganal-Vonarburg, Andrew J. Macpherson, Melanie Meyer-Luehmann, Peter Staeheli, Thomas Blank, Marco Prinz and Daniel Erny

    Citation: Acta Neuropathologica Communications 2020 8:119

    Content type: Research

    Published on:

  44. The deposition of neurotoxic amyloid-β (Aβ) peptides in extracellular plaques in the brain parenchyma is one of the most prominent neuropathological features of Alzheimer’s disease (AD), and considered to be c...

    Authors: Sathish Kumar, Cynthia A. Lemere and Jochen Walter

    Citation: Acta Neuropathologica Communications 2020 8:118

    Content type: Research

    Published on:

  45. Tissue accumulation of abnormal aggregates of amyloidogenic proteins such as prion protein, α-synuclein, and tau represents the hallmark of most common neurodegenerative disorders and precedes the onset of sym...

    Authors: Niccolò Candelise, Simone Baiardi, Alessia Franceschini, Marcello Rossi and Piero Parchi

    Citation: Acta Neuropathologica Communications 2020 8:117

    Content type: Review

    Published on:

  46. Protein inclusions containing the RNA-binding protein TDP-43 are a pathological hallmark of amyotrophic lateral sclerosis and other neurodegenerative disorders. The loss of TDP-43 function that is associated w...

    Authors: Michael Briese, Lena Saal-Bauernschubert, Patrick Lüningschrör, Mehri Moradi, Benjamin Dombert, Verena Surrey, Silke Appenzeller, Chunchu Deng, Sibylle Jablonka and Michael Sendtner

    Citation: Acta Neuropathologica Communications 2020 8:116

    Content type: Research

    Published on:

  47. A case of a true dual-genotype IDH-mutant oligoastrocytoma with two different cell types within a single mass in a young woman is presented. Imaging findings of the left frontal infiltrating glioma predicted the ...

    Authors: Mac Lean P. Nasrallah, Arati Desai, Donald M. O’Rourke, Lea F. Surrey and Joel M. Stein

    Citation: Acta Neuropathologica Communications 2020 8:115

    Content type: Case report

    Published on:

  48. Meningiomas are the most common primary intracranial tumors, but treatment options for meningioma patients are limited due to incomplete understanding of tumor biology. A small percentage of meningiomas harbor...

    Authors: Sarah Findakly, Abrar Choudhury, Vikas Daggubati, Melike Pekmezci, Ursula E. Lang and David R. Raleigh

    Citation: Acta Neuropathologica Communications 2020 8:114

    Content type: Research

    Published on:

  49. Inflammatory orbital lesions include a broad list of diagnoses, many of them with overlapping clinical and radiographic features. They often present a diagnostic conundrum, even to the most experienced orbital...

    Authors: Nishanth S. Iyengar, Danielle Golub, Michelle W. McQuinn, Travis Hill, Karen Tang, Sharon L. Gardner, David H. Harter, Chandranath Sen, David A. Staffenberg, Kristen Thomas, Zachary Elkin, Irina Belinsky and Christopher William

    Citation: Acta Neuropathologica Communications 2020 8:113

    Content type: Case report

    Published on:

Annual Journal Metrics