Anastasaki C, Gutmann DH (2014) Neuronal NF1/RAS regulation of cyclic AMP requires atypical PKC activation. Hum Mol Genet 23(25):6712–21.
Article
PubMed
PubMed Central
CAS
Google Scholar
Antonioli L, Blandizzi C, Pacher P, Haskó G (2013) Immunity, inflammation and cancer: a leading role for adenosine. Nat Rev Cancer 13(12):842–857
Article
PubMed
CAS
Google Scholar
Atanasoski S, Notterpek L, Lee H-Y, Castagner F, Young P, Ehrengruber MU, Meijer D, Sommer L, Stavnezer E, Colmenares C (2004) The protooncogene ski controls Schwann cell proliferation and myelination. Neuron 43(4):499–511
Article
PubMed
CAS
Google Scholar
Bagchi S, Liao Z, Gonzalez FA, Chorna NE, Seye CI, Weisman GA, Erb L (2005) The P2Y2 nucleotide receptor interacts with αv integrins to activate go and induce cell migration. J Biol Chem 280(47):39050–39057
Article
PubMed
CAS
Google Scholar
Beaulieu JM, Marion S, Rodriguiz RM, Medvedev IO, Sotnikova TD, Ghisi V, Wetsel WC, Lefkowitz RJ, Gainetdinov RR, Caron MG (2008) A beta-arrestin 2 signaling complex mediates lithium action on behavior. Cell 132(1):125–136
Article
PubMed
CAS
Google Scholar
Beaulieu J-M, Sotnikova TD, Marion S, Lefkowitz RJ, Gainetdinov RR, Caron MG (2005) An Akt/β-Arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior. Cell 122(2):261–273
Article
PubMed
CAS
Google Scholar
Beautrait A, Paradis JS, Zimmerman B, Giubilaro J, Nikolajev L, Armando S, Kobayashi H, Yamani L, Namkung Y, Heydenreich FM et al (2017) A new inhibitor of the beta-arrestin/AP2 endocytic complex reveals interplay between GPCR internalization and signalling. Nat Commun 8:15054
Article
PubMed
PubMed Central
CAS
Google Scholar
Cekic C, Linden J (2016) Purinergic regulation of the immune system. Nat Rev Immunol 16(3):177–192
Article
PubMed
CAS
Google Scholar
Chen S, Xia S, Sun Y, Li M, Song X, Li G, Zheng H, Chen D (2015) Expression of purinergic receptor P2Y4 in Schwann cell following nerve regeneration. Int J Clin Exp Med 8(8):13203
PubMed
PubMed Central
CAS
Google Scholar
Chen Y, Zhang X, Wang C, Li G, Gu Y, Huang L-YM (2008) Activation of P2X7 receptors in glial satellite cells reduces pain through downregulation of P2X3 receptors in nociceptive neurons. Proc Natl Acad Sci 105(43):16773–16778
Article
PubMed
PubMed Central
Google Scholar
Clemence A, Mirsky R, Jessen K (1989) Non-myelin-forming Schwann cells proliferate rapidly during Wallerian degeneration in the rat sciatic nerve. J Neurocytol 18(2):185–192
Article
PubMed
CAS
Google Scholar
Coutinho-Silva R, Ojcius DM, Gorecki DC, Persechini PM, Bisaggio RC, Mendes AN, Marks J, Burnstock G, Dunn PM (2005) Multiple P2X and P2Y receptor subtypes in mouse J774, spleen and peritoneal macrophages. Biochem Pharmacol 69(4):641–655
Article
PubMed
CAS
Google Scholar
Deraredj Nadim W, Chaumont-Dubel S, Madouri F, Cobret L, De Tauzia M-L, Zajdel P, Bénédetti H, Marin P, Morisset-Lopez S (2016) Physical interaction between neurofibromin and serotonin 5-HT<sub>6</sub> receptor promotes receptor constitutive activity. Proc Natl Acad Sci 113(43):12310–12315
Article
PubMed
CAS
PubMed Central
Google Scholar
DeWire SM, Ahn S, Lefkowitz RJ, Shenoy SK (2007) Beta-arrestins and cell signaling. Annu Rev Physiol 69:483–510
Article
PubMed
CAS
Google Scholar
Di Virgilio F, Adinolfi E (2017) Extracellular purines, purinergic receptors and tumor growth. Oncogene 36(3):293–303
Diaz-Flores E, Goldschmidt H, Depeille P, Ng V, Akutagawa J, Krisman K, Crone M, Burgess MR, Williams O, Houseman B et al (2013) PLC-gamma and PI3K link cytokines to ERK activation in hematopoietic cells with normal and oncogenic Kras. Sci Signal 6(304):ra105
Article
PubMed
PubMed Central
CAS
Google Scholar
Dombi E, Baldwin A, Marcus LJ, Fisher MJ, Weiss B, Kim A, Whitcomb P, Martin S, Aschbacher-Smith LE, Rizvi TA (2016) Activity of Selumetinib in Neurofibromatosis type 1–related plexiform Neurofibromas. N Engl J Med 375(26):2550–2560
Article
PubMed
PubMed Central
CAS
Google Scholar
Domenech-Estevez E, Baloui H, Meng X, Zhang Y, Deinhardt K, Dupree JL, Einheber S, Chrast R, Salzer JL (2016) Akt regulates axon wrapping and myelin sheath thickness in the PNS. J Neurosci 36(16):4506–4521
Article
PubMed
PubMed Central
CAS
Google Scholar
Elliott MR, Chekeni FB, Trampont PC, Lazarowski ER, Kadl A, Walk SF, Park D, Woodson RI, Ostankovich M, Sharma P et al (2009) Nucleotides released by apoptotic cells act as a find-me signal to promote phagocytic clearance. Nature 461(7261):282–286
Article
PubMed
PubMed Central
CAS
Google Scholar
Faroni A, Rothwell S, Grolla A, Terenghi G, Magnaghi V, Verkhratsky A (2013) Differentiation of adipose-derived stem cells into Schwann cell phenotype induces expression of P2X receptors that control cell death. Cell Death Dis 4(7):e743
Article
PubMed
PubMed Central
CAS
Google Scholar
Faroni A, Smith R, Procacci P, Castelnovo L, Puccianti E, Reid A, Magnaghi V, Verkhratsky A (2014) Purinergic signaling mediated by P2X7 receptors controls myelination in sciatic nerves. J Neurosci Res 92(10):1259–1269
Article
PubMed
CAS
Google Scholar
Feltri ML, Poitelon Y, Previtali SC (2015) How Schwann cells Sort axons new concepts. Neuroscientist. https://doi.org/10.1177/1073858415572361
Article
PubMed
CAS
Google Scholar
Fields RD, Ni Y (2010) Nonsynaptic communication through ATP release from volume-activated anion channels in axons. Sci Signal 3(142):ra73
Article
PubMed
PubMed Central
CAS
Google Scholar
Forester CM, Maddox J, Louis JV, Goris J, Virshup DM (2007) Control of mitotic exit by PP2A regulation of Cdc25C and Cdk1. Proc Natl Acad Sci U S A 104(50):19867–19872
Article
PubMed
PubMed Central
Google Scholar
Fritsch R, de Krijger I, Fritsch K, George R, Reason B, Kumar MS, Diefenbacher M, Stamp G, Downward J (2013) RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms. Cell 153(5):1050–1063
Article
PubMed
PubMed Central
CAS
Google Scholar
Fuchs S, Herzog D, Sumara G, Büchmann-Møller S, Civenni G, Wu X, Chrostek-Grashoff A, Suter U, Ricci R, Relvas JB (2009) Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1. Cell Stem Cell 4(3):236–247
Article
PubMed
CAS
Google Scholar
Grigoryan T, Birchmeier W (2015) Molecular signaling mechanisms of axon–glia communication in the peripheral nervous system. BioEssays 37(5):502–513
Article
PubMed
Google Scholar
Grundmann M, Merten N, Malfacini D, Inoue A, Preis P, Simon K, Ruttiger N, Ziegler N, Benkel T, Schmitt NK et al (2018) Lack of beta-arrestin signaling in the absence of active G proteins. Nat Commun 9(1):341
Article
PubMed
PubMed Central
CAS
Google Scholar
Guo H-F, Tong J, Hannan F, Luo L, Zhong Y (2000) A neurofibromatosis-1-regulated pathway is required for learning in drosophila. Nature 403:895
Article
PubMed
CAS
Google Scholar
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: the next generation. Cell 144(5):646–674
Article
CAS
PubMed
Google Scholar
Huson S, Compston D, Clark P, Harper P (1989) A genetic study of von Recklinghausen neurofibromatosis in south East Wales. I. Prevalence, fitness, mutation rate, and effect of parental transmission on severity. J Med Genet 26(11):704–711
Article
PubMed
PubMed Central
CAS
Google Scholar
Ino D, Sagara H, Suzuki J, Kanemaru K, Okubo Y, Iino M (2015) Neuronal regulation of Schwann cell mitochondrial ca 2+ signaling during myelination. Cell Rep 12(12):1951–1959
Article
PubMed
CAS
Google Scholar
Jaegle M, Ghazvini M, Mandemakers W, Piirsoo M, Driegen S, Levavasseur F, Raghoenath S, Grosveld F, Meijer D (2003) The POU proteins Brn-2 and Oct-6 share important functions in Schwann cell development. Genes Dev 17(11):1380–1391
Article
PubMed
PubMed Central
CAS
Google Scholar
Jessen KR, Mirsky R (2005) The origin and development of glial cells in peripheral nerves. Nat Rev Neurosci 6(9):671–682
Article
PubMed
CAS
Google Scholar
Jessen WJ, Miller SJ, Jousma E, Wu J, Rizvi TA, Brundage ME, Eaves D, Widemann B, Kim M-O, Dombi E (2013) MEK inhibition exhibits efficacy in human and mouse neurofibromatosis tumors. J Clin Invest 123(1):340–347
Article
PubMed
CAS
Google Scholar
Jung J, Jo HW, Kwon H, Jeong NY (2014) ATP release through lysosomal exocytosis from peripheral nerves: the effect of lysosomal exocytosis on peripheral nerve degeneration and regeneration after nerve injury. Biomed Res Int 2014:1–6. https://doi.org/10.1155/2014/936891
CAS
Google Scholar
Kara E, Crepieux P, Gauthier C, Martinat N, Piketty V, Guillou F, Reiter E (2006) A phosphorylation cluster of five serine and threonine residues in the C-terminus of the follicle-stimulating hormone receptor is important for desensitization but not for beta-arrestin-mediated ERK activation. Mol Endocrinol 20(11):3014–3026
Article
PubMed
CAS
Google Scholar
Kendall RT, Strungs EG, Rachidi SM, Lee MH, El-Shewy HM, Luttrell DK, Janech MG, Luttrell LM (2011) The beta-arrestin pathway-selective type 1A angiotensin receptor (AT1A) agonist [Sar1,Ile4,Ile8]angiotensin II regulates a robust G protein-independent signaling network. J Biol Chem 286(22):19880–19891
Article
PubMed
PubMed Central
CAS
Google Scholar
Kim HA, Rosenbaum T, Marchionni MA, Ratner N, DeClue JE (1995) Schwann cells from neurofibromin deficient mice exhibit activation of p21ras, inhibition of cell proliferation and morphological changes. Oncogene 11(2):325–335
PubMed
CAS
Google Scholar
Kimura T, Han W, Pagel P, Nairn AC, Caplan MJ (2011) Protein phosphatase 2A interacts with the Na,K-ATPase and modulates its trafficking by inhibition of its association with arrestin. PLoS One 6(12):e29269
Article
PubMed
PubMed Central
CAS
Google Scholar
Knoblich JA (2010) Asymmetric cell division: recent developments and their implications for tumour biology. Nat Rev Mol Cell Biol 11:849
Article
PubMed
PubMed Central
CAS
Google Scholar
Komiyama A, Suzuki K (1992) Age-related differences in proliferative responses of Schwann cells during Wallerian degeneration. Brain Res 573(2):267–275
Article
PubMed
CAS
Google Scholar
Kroeze WK, Sassano MF, Huang XP, Lansu K, McCorvy JD, Giguere PM, Sciaky N, Roth BL (2015) PRESTO-tango as an open-source resource for interrogation of the druggable human GPCRome. Nat Struct Mol Biol 22(5):362–369
Article
PubMed
PubMed Central
CAS
Google Scholar
Lamarca A, Gella A, Martianez T, Segura M, Figueiro-Silva J, Grijota-Martinez C, Trullas R, Casals N (2014) Uridine 5′-triphosphate promotes in vitro schwannoma cell migration through matrix metalloproteinase-2 activation. PLoS One 9(6):e98998
Article
PubMed
PubMed Central
CAS
Google Scholar
Lefkowitz RJ, Rajagopal K, Whalen EJ (2006) New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors. Mol Cell 24(5):643–652
Article
PubMed
CAS
Google Scholar
Li H, Chang LJ, Neubauer DR, Muir DF, Wallace MR (2016) Immortalization of human normal and NF1 neurofibroma Schwann cells. Lab Investig 96(10):1105–1115
Article
PubMed
CAS
Google Scholar
Li J, Walker SM, Fitzgerald M, Baccei ML (2009) Activity-dependent modulation of glutamatergic signaling in the developing rat dorsal horn by early tissue injury. J Neurophysiol 102(4):2208–2219
Article
PubMed
PubMed Central
CAS
Google Scholar
Li Y, Tennekoon GI, Birnbaum M, Marchionni MA, Rutkowski JL (2001) Neuregulin signaling through a PI3K/Akt/bad pathway in Schwann cell survival. Mol Cell Neurosci 17(4):761–767
Article
PubMed
CAS
Google Scholar
Liao Y, Hung M-C (2010) Physiological regulation of Akt activity and stability. Am J Transl Res 2(1):19–42
PubMed
PubMed Central
CAS
Google Scholar
Liu GJ, Werry EL, Bennett MR (2005) Secretion of ATP from Schwann cells in response to uridine triphosphate. Eur J Neurosci 21(1):151–160
Article
PubMed
Google Scholar
Liu HM, Yang LH, Yang YJ (1995) Schwann cell properties: 3. C-fos expression, bFGF production, phagocytosis and proliferation during Wallerian degeneration. J Neuropathol Exp Neurol 54(4):487–496
Article
PubMed
CAS
Google Scholar
Madry C, Arancibia-Carcamo IL, Kyrargyri V, Chan VTT, Hamilton NB, Attwell D (2018) Effects of the ecto-ATPase apyrase on microglial ramification and surveillance reflect cell depolarization, not ATP depletion. Proc Natl Acad Sci U S A 115(7):E1608–E1617
Article
PubMed
PubMed Central
CAS
Google Scholar
Martinez NA, Ayala AM, Martinez M, Martinez-Rivera FJ, Miranda JD, Silva WI (2016) Caveolin-1 regulates the P2Y2 receptor signaling in human 1321N1 astrocytoma cells. J Biol Chem 291(23):12208–12222
Article
PubMed
PubMed Central
CAS
Google Scholar
Martinov VN, Njå A (2005) A microcapsule technique for long-term conduction block of the sciatic nerve by tetrodotoxin. J Neurosci Methods 141(2):199–205
Article
PubMed
CAS
Google Scholar
Masgras I, Ciscato F, Brunati AM, Tibaldi E, Indraccolo S, Curtarello M, Chiara F, Cannino G, Papaleo E, Lambrughi M et al (2017) Absence of Neurofibromin induces an oncogenic metabolic switch via mitochondrial ERK-mediated phosphorylation of the chaperone TRAP1. Cell Rep 18(3):659–672
Article
PubMed
CAS
Google Scholar
Mautner VF, Asuagbor FA, Dombi E, Funsterer C, Kluwe L, Wenzel R, Widemann BC, Friedman JM (2008) Assessment of benign tumor burden by whole-body MRI in patients with neurofibromatosis 1. Neuro-Oncology 10(4):593–598
Article
PubMed
PubMed Central
Google Scholar
Monje PV, Athauda G, Wood PM (2008) Protein kinase A-mediated gating of neuregulin-dependent ErbB2-ErbB3 activation underlies the synergistic action of cAMP on Schwann cell proliferation. J Biol Chem 283(49):34087–34100
Article
PubMed
PubMed Central
CAS
Google Scholar
Morris GE, Nelson CP, Brighton PJ, Standen NB, Challiss RA, Willets JM (2012) Arrestins 2 and 3 differentially regulate ETA and P2Y2 receptor-mediated cell signaling and migration in arterial smooth muscle. Am J Physiol Cell Physiol 302(5):C723–C734
Article
PubMed
CAS
Google Scholar
Neviani P, Harb JG, Oaks JJ, Santhanam R, Walker CJ, Ellis JJ, Ferenchak G, Dorrance AM, Paisie CA, Eiring AM et al (2013) PP2A-activating drugs selectively eradicate TKI-resistant chronic myeloid leukemic stem cells. J Clin Invest 123(10):4144–4157
Article
PubMed
PubMed Central
CAS
Google Scholar
Nobbio L, Visigalli D, Mannino E, Fiorese F, Kassack MU, Sturla L, Prada V, De Flora A, Zocchi E, Bruzzone S (2014) The Diadenosine Homodinucleotide P18 improves in vitro myelination in experimental Charcot-Marie-tooth type 1A. J Cell Biochem 115(1):161–167
Article
PubMed
CAS
Google Scholar
Nualart-Marti A, Molino EM, Grandes X, Bahima L, Martin-Satué M, Puchal R, Fasciani I, González-Nieto D, Ziganshin B, Llobet A (2013) Role of connexin 32 hemichannels in the release of ATP from peripheral nerves. Glia 61(12):1976–1989
Article
PubMed
Google Scholar
Pellegatti P, Raffaghello L, Bianchi G, Piccardi F, Pistoia V, Di Virgilio F (2008) Increased level of extracellular ATP at tumor sites: in vivo imaging with plasma membrane luciferase. PLoS One 3(7):e2599
Article
PubMed
PubMed Central
CAS
Google Scholar
Pemov A, Li H, Patidar R, Hansen NF, Sindiri S, Hartley SW, Wei JS, Elkahloun A, Chandrasekharappa SC, Program NCS et al (2017) The primacy of NF1 loss as the driver of tumorigenesis in neurofibromatosis type 1-associated plexiform neurofibromas. Oncogene 36(22):3168–3177
Article
PubMed
CAS
PubMed Central
Google Scholar
Peterson YK, Luttrell LM (2017) The diverse roles of Arrestin scaffolds in G protein–coupled receptor signaling. Pharmacol Rev 69(3):256–297
Article
PubMed
PubMed Central
CAS
Google Scholar
Prada CE, Jousma E, Rizvi TA, Wu J, Dunn RS, Mayes DA, Cancelas JA, Dombi E, Kim MO, West BL et al (2013) Neurofibroma-associated macrophages play roles in tumor growth and response to pharmacological inhibition. Acta Neuropathol 125(1):159–168
Article
PubMed
CAS
Google Scholar
Prada CE, Rangwala FA, Martin LJ, Lovell AM, Saal HM, Schorry EK, Hopkin RJ (2012) Pediatric plexiform neurofibromas: impact on morbidity and mortality in neurofibromatosis type 1. J Pediatr 160(3):461–467
Article
PubMed
Google Scholar
Rafehi M, Burbiel JC, Attah IY, Abdelrahman A, Müller CE (2017) Synthesis, characterization, and in vitro evaluation of the selective P2Y2 receptor antagonist AR-C118925. Purinergic Signal 13(1):89–103
Article
PubMed
CAS
Google Scholar
Rajagopal S, Shenoy SK (2017) GPCR desensitization: acute and prolonged phases. Cell Signal
Rasband MN, Peles E (2015) The nodes of Ranvier: molecular assembly and maintenance. Cold Spring Harb Perspect Biol 8(3):a020495
Article
PubMed
Google Scholar
Ratner N, Miller SJ (2015) A RASopathy gene commonly mutated in cancer: the neurofibromatosis type 1 tumour suppressor. Nat Rev Cancer 15(5):290–301
Article
PubMed
PubMed Central
CAS
Google Scholar
Ruvolo PP (2016) The broken “off” switch in cancer signaling: PP2A as a regulator of tumorigenesis, drug resistance, and immune surveillance. BBA Clin 6:87–99
Article
PubMed
PubMed Central
Google Scholar
Salzer JL, Bunge RP (1980) Studies of Schwann cell proliferation. I. an analysis in tissue culture of proliferation during development, Wallerian degeneration, and direct injury. J Cell Biol 84(3):739–752
Article
PubMed
CAS
Google Scholar
Sangodkar J, Perl A, Tohme R, Kiselar J, Kastrinsky DB, Zaware N, Izadmehr S, Mazhar S, Wiredja DD, O'Connor CM et al (2017) Activation of tumor suppressor protein PP2A inhibits KRAS-driven tumor growth. J Clin Invest 127(6):2081–2090
Article
PubMed
PubMed Central
Google Scholar
Serra E, Rosenbaum T, Winner U, Aledo R, Ars E, Estivill X, Lenard HG, Lazaro C (2000) Schwann cells harbor the somatic NF1 mutation in neurofibromas: evidence of two different Schwann cell subpopulations. Hum Mol Genet 9(20):3055–3064
Article
PubMed
CAS
Google Scholar
Seye CI, Yu N, González FA, Erb L, Weisman GA (2004) The P2Y2 nucleotide receptor mediates vascular cell adhesion molecule-1 expression through interaction with VEGF receptor-2 (KDR/Flk-1). J Biol Chem 279(34):35679–35686
Article
PubMed
CAS
Google Scholar
Shin YH, Chung H-J, Park C, Jung J, Jeong NY (2014) Adenosine 5′-triphosphate (ATP) inhibits schwann cell demyelination during Wallerian degeneration. Cell Mol Neurobiol 34(3):361–368
Article
PubMed
CAS
Google Scholar
Simanshu DK, Nissley DV, McCormick F (2017) RAS proteins and their regulators in human disease. Cell 170(1):17–33
Article
PubMed
PubMed Central
CAS
Google Scholar
Song G, Ouyang G, Bao S (2005) The activation of Akt/PKB signaling pathway and cell survival. J Cell Mol Med 9(1):59–71
Article
PubMed
CAS
PubMed Central
Google Scholar
Stevens B, Fields RD (2000) Response of Schwann cells to action potentials in development. Science 287(5461):2267–2271
Article
PubMed
CAS
Google Scholar
Stevens B, Ishibashi T, Chen J-F, Fields RD (2004) Adenosine: an activity-dependent axonal signal regulating MAP kinase and proliferation in developing Schwann cells. Neuron Glia Biol 1(01):23–34
Article
PubMed
PubMed Central
Google Scholar
Stevens B, Porta S, Haak LL, Gallo V, Fields RD (2002) Adenosine: a neuron-glial transmitter promoting myelination in the CNS in response to action potentials. Neuron 36(5):855–868
Article
PubMed
PubMed Central
CAS
Google Scholar
Tsutsui S, Schnermann J, Noorbakhsh F, Henry S, Yong VW, Winston BW, Warren K, Power C (2004) A1 adenosine receptor upregulation and activation attenuates neuroinflammation and demyelination in a model of multiple sclerosis. J Neurosci 24(6):1521–1529
Article
PubMed
CAS
PubMed Central
Google Scholar
von Kügelgen I (2006) Pharmacological profiles of cloned mammalian P2Y-receptor subtypes. Pharmacol Ther 110(3):415–432
Article
PubMed
CAS
Google Scholar
Vono M, Taccone M, Caccin P, Gallotta M, Donvito G, Falzoni S, Palmieri E, Pallaoro M, Rappuoli R, Di Virgilio F et al (2013) The adjuvant MF59 induces ATP release from muscle that potentiates response to vaccination. Proc Natl Acad Sci 110(52):21095–21100
Article
PubMed
CAS
PubMed Central
Google Scholar
Waldo GL, Harden TK (2004) Agonist binding and Gq-stimulating activities of the purified human P2Y1 receptor. Mol Pharmacol 65(2):426–436
Article
PubMed
CAS
Google Scholar
Walsh AH, Cheng A, Honkanen RE (1997) Fostriecin, an antitumor antibiotic with inhibitory activity against serine/threonine protein phosphatases types 1 (PP1) and 2A (PP2A), is highly selective for PP2A. FEBS Lett 416(3):230–234
Article
PubMed
CAS
Google Scholar
Wilson GF, Chiu SY (1993) Mitogenic factors regulate ion channels in Schwann cells cultured from newborn rat sciatic nerve. J Physiol 470:501–520
Article
PubMed
PubMed Central
CAS
Google Scholar
Woodhoo A, Sommer L (2008) Development of the Schwann cell lineage: from the neural crest to the myelinated nerve. Glia 56(14):1481–1490
Article
PubMed
Google Scholar
Wu J, Williams JP, Rizvi TA, Kordich JJ, Witte D, Meijer D, Stemmer-Rachamimov AO, Cancelas JA, Ratner N (2008) Plexiform and dermal neurofibromas and pigmentation are caused by Nf1 loss in desert hedgehog-expressing cells. Cancer Cell 13(2):105–116
Article
PubMed
PubMed Central
CAS
Google Scholar
Xiao K, McClatchy DB, Shukla AK, Zhao Y, Chen M, Shenoy SK, Yates JR 3rd, Lefkowitz RJ (2007) Functional specialization of beta-arrestin interactions revealed by proteomic analysis. Proc Natl Acad Sci U S A 104(29):12011–12016
Article
PubMed
PubMed Central
CAS
Google Scholar
Xie W, Strong JA, Meij JT, Zhang JM, Yu L (2005) Neuropathic pain: early spontaneous afferent activity is the trigger. Pain 116(3):243–256
Article
PubMed
PubMed Central
Google Scholar
Yang FC, Ingram DA, Chen S, Zhu Y, Yuan J, Li X, Yang X, Knowles S, Horn W, Li Y et al (2008) Nf1-dependent tumors require a microenvironment containing Nf1+/−− and c-kit-dependent bone marrow. Cell 135(3):437–448
Article
PubMed
PubMed Central
CAS
Google Scholar
Yang S, Abrahams MS, Hurn PD, Grafe MR, Kirsch JR (2011) Local anesthetic Schwann cell toxicity is time and concentration dependent. Reg Anesth Pain Med 36(5):444–451
Article
PubMed
PubMed Central
CAS
Google Scholar
Zhang JM, Homma Y, Ackerman WE, Brull SJ (2001) Topical application of acidic bupivacaine to the lumbar ganglion induces mechanical hyperalgesia in the rat. Anesth Analg 93(2):466–471 464th contents page
PubMed
CAS
Google Scholar