Agnihotri S, Suppiah S, Tonge PD, Jalali S, Danesh A, Bruce JP, Mamatjan Y, Klironomos G, Gonen L, Au K et al (2017) Therapeutic radiation for childhood cancer drives structural aberrations of NF2 in meningiomas. Nat Commun 8:186. https://doi.org/10.1038/s41467-017-00174-7
Article
CAS
PubMed
PubMed Central
Google Scholar
Anders S, Huber W (2010) Differential expression analysis for sequence count data. Genome Biol 11:R106. https://doi.org/10.1186/gb-2010-11-10-r106
Article
CAS
PubMed
PubMed Central
Google Scholar
Bayne RA, Donnachie DJ, Kinnell HL, Childs AJ, Anderson RA (2016) BMP signalling in human fetal ovary somatic cells is modulated in a gene-specific fashion by GREM1 and GREM2. Mol Hum Reprod 22:622–633. https://doi.org/10.1093/molehr/gaw044
Article
CAS
PubMed
PubMed Central
Google Scholar
Bello MJ, de Campos JM, Kusak ME, Vaquero J, Sarasa JL, Pestana A, Rey JA (1994) Allelic loss at 1p is associated with tumor progression of meningiomas. Genes, chromosomes & cancer 9:296–298
Article
CAS
Google Scholar
Bi WL, Greenwald NF, Abedalthagafi M, Wala J, Gibson WJ, Agarwalla PK, Horowitz P, Schumacher SE, Esaulova E, Mei Y et al (2017) Genomic landscape of high-grade meningiomas. NPJ Genom med 2. https://doi.org/10.1038/s41525-017-0014-7
Boetto J, Apra C, Bielle F, Peyre M, Kalamarides M (2018) Selective vulnerability of the primitive meningeal layer to prenatal Smo activation for skull base meningothelial meningioma formation. Oncogene 37:4955–4963. https://doi.org/10.1038/s41388-018-0328-7
Article
CAS
PubMed
Google Scholar
Brastianos PK, Horowitz PM, Santagata S, Jones RT, McKenna A, Getz G, Ligon KL, Palescandolo E, Van Hummelen P, Ducar MD et al (2013) Genomic sequencing of meningiomas identifies oncogenic SMO and AKT1 mutations. Nat Genet 45:285–289. https://doi.org/10.1038/ng.2526
Article
CAS
PubMed
PubMed Central
Google Scholar
Brazil DP, Church RH, Surae S, Godson C, Martin F (2015) BMP signalling: agony and antagony in the family. Trends Cell Biol 25:249–264. https://doi.org/10.1016/j.tcb.2014.12.004
Article
CAS
PubMed
Google Scholar
Cavaille J (2017) Box C/D small nucleolar RNA genes and the Prader-Willi syndrome: a complex interplay. Wiley interdiscip Rev RNA 8. https://doi.org/10.1002/wrna.1417
Article
Google Scholar
Clark VE, Erson-Omay EZ, Serin A, Yin J, Cotney J, Ozduman K, Avsar T, Li J, Murray PB, Henegariu O et al (2013) Genomic analysis of non-NF2 meningiomas reveals mutations in TRAF7, KLF4, AKT1, and SMO. Science 339:1077–1080. https://doi.org/10.1126/science.1233009
Article
CAS
PubMed
PubMed Central
Google Scholar
Clark VE, Harmanci AS, Bai H, Youngblood MW, Lee TI, Baranoski JF, Ercan-Sencicek AG, Abraham BJ, Weintraub AS, Hnisz D et al (2016) Recurrent somatic mutations in POLR2A define a distinct subset of meningiomas. Nat Genet 48:1253–1259. https://doi.org/10.1038/ng.3651
Article
CAS
PubMed
PubMed Central
Google Scholar
Collord G, Tarpey P, Kurbatova N, Martincorena I, Moran S, Castro M, Nagy T, Bignell G, Maura F, Young MD et al (2018) An integrated genomic analysis of anaplastic meningioma identifies prognostic molecular signatures. Scientific reports 8:13537. https://doi.org/10.1038/s41598-018-31659-0
Article
CAS
PubMed
PubMed Central
Google Scholar
Di Stefano AL, Fucci A, Frattini V, Labussiere M, Mokhtari K, Zoppoli P, Marie Y, Bruno A, Boisselier B, al GM (2015) Detection, characterization, and inhibition of FGFR-TACC fusions in IDH wild-type glioma. Clin Cancer Res 21:3307–3317. https://doi.org/10.1158/1078-0432.CCR-14-2199
Article
CAS
PubMed
PubMed Central
Google Scholar
Dobin A, Davis CA, Schlesinger F, Drenkow J, Zaleski C, Jha S, Batut P, Chaisson M, Gingeras TR (2013) STAR: ultrafast universal RNA-seq aligner. Bioinformatics 29:15–21. https://doi.org/10.1093/bioinformatics/bts635
Article
CAS
PubMed
Google Scholar
Domingues P, Gonzalez-Tablas M, Otero A, Pascual D, Ruiz L, Miranda D, Sousa P, Goncalves JM, Lopes MC, Orfao A et al (2015) Genetic/molecular alterations of meningiomas and the signaling pathways targeted. Oncotarget 6:10671–10688. https://doi.org/10.18632/oncotarget.3870
Article
PubMed
PubMed Central
Google Scholar
Du Z, Abedalthagafi M, Aizer AA, McHenry AR, Sun HH, Bray MA, Viramontes O, Machaidze R, Brastianos PK, Reardon DA et al (2015) Increased expression of the immune modulatory molecule PD-L1 (CD274) in anaplastic meningioma. Oncotarget 6:4704–4716. https://doi.org/10.18632/oncotarget.3082
Article
PubMed
Google Scholar
Gao F, Ling C, Shi L, Commins D, Zada G, Mack WJ, Wang K (2013) Inversion-mediated gene fusions involving NAB2-STAT6 in an unusual malignant meningioma. Br J Cancer 109:1051–1055. https://doi.org/10.1038/bjc.2013.395
Article
CAS
PubMed
PubMed Central
Google Scholar
Goldbrunner R, Minniti G, Preusser M, Jenkinson MD, Sallabanda K, Houdart E, von Deimling A, Stavrinou P, Lefranc F, Lund-Johansen M et al (2016) EANO guidelines for the diagnosis and treatment of meningiomas. The Lancet Oncol 17:e383–e391. https://doi.org/10.1016/s1470-2045(16)30321-7
Article
PubMed
Google Scholar
Gong J, Li Y, Liu CJ, Xiang Y, Li C, Ye Y, Zhang Z, Hawke DH, Park PK, Diao L et al (2017) A pan-cancer analysis of the expression and clinical relevance of small nucleolar RNAs in human Cancer. Cell Rep 21:1968–1981. https://doi.org/10.1016/j.celrep.2017.10.070
Article
CAS
PubMed
Google Scholar
Guan Y, Cheng W, Zou C, Wang T, Cao Z (2017) Gremlin1 promotes carcinogenesis of glioma in vitro. Clin Exp Pharmacol Physiol 44:244–256. https://doi.org/10.1111/1440-1681.12697
Article
CAS
PubMed
Google Scholar
Haas B, Dobin A, Stransky N, Li B, Yang X, Tickle T, Bankapur A, Ganote C, Doak T, Pochet N et al (2017) STAR-fusion: fast and accurate fusion transcript detection from RNA-Seq. In: bioRxiv. https://doi.org/10.1101/120295
Chapter
Google Scholar
Han SJ, Reis G, Kohanbash G, Shrivastav S, Magill ST, Molinaro AM, McDermott MW, Theodosopoulos PV, Aghi MK, Berger MS et al (2016) Expression and prognostic impact of immune modulatory molecule PD-L1 in meningioma. J Neuro-Oncol 130:543–552. https://doi.org/10.1007/s11060-016-2256-0
Article
CAS
Google Scholar
Ikeda H, Tsuyuguchi N, Kunihiro N, Ishibashi K, Goto T, Ohata K (2013) Analysis of progression and recurrence of meningioma using (11) C-methionine PET. Ann Nucl Med 27:772–780. https://doi.org/10.1007/s12149-013-0747-z
Article
CAS
PubMed
Google Scholar
Iwatate K, Yokoo T, Iwatate E, Ichikawa M, Sato T, Fujii M, Sakuma J, Saito K (2017) Population characteristics and progressive disability in Neurofibromatosis type 2. World Neurosurg 106:653–660. https://doi.org/10.1016/j.wneu.2017.07.036
Article
PubMed
Google Scholar
Jenkinson EM, Rodero MP, Kasher PR, Uggenti C, Oojageer A, Goosey LC, Rose Y, Kershaw CJ, Urquhart JE, Williams SG et al (2016) Mutations in SNORD118 cause the cerebral microangiopathy leukoencephalopathy with calcifications and cysts. Nat Genet 48:1185–1192. https://doi.org/10.1038/ng.3661
Article
CAS
PubMed
PubMed Central
Google Scholar
Johnson MD (2017) Transforming growth factor Beta family in the pathogenesis of Meningiomas. World Neurosurg 104:113–119. https://doi.org/10.1016/j.wneu.2017.03.058
Article
PubMed
Google Scholar
Johnson MD, O'Connell MJ, Vito F, Pilcher W (2009) Bone morphogenetic protein 4 and its receptors are expressed in the leptomeninges and meningiomas and signal via the Smad pathway. J Neuropathol Exp Neurol 68:1177–1183. https://doi.org/10.1097/NEN.0b013e3181bc6642
Article
CAS
PubMed
Google Scholar
Kanno H, Nishihara H, Wang L, Yuzawa S, Kobayashi H, Tsuda M, Kimura T, Tanino M, Terasaka S, Tanaka S (2013) Expression of CD163 prevents apoptosis through the production of granulocyte colony-stimulating factor in meningioma. Neuro-Oncology 15:853–864. https://doi.org/10.1093/neuonc/not028
Article
CAS
PubMed
PubMed Central
Google Scholar
Karsy M, Azab MA, Abou-Al-Shaar H, Guan J, Eli I, Jensen RL, Ormond DR (2018) Clinical potential of meningioma genomic insights: a practical review for neurosurgeons. Neurosurg Focus 44:E10. https://doi.org/10.3171/2018.2.FOCUS1849
Article
PubMed
Google Scholar
Katz LM, Hielscher T, Liechty B, Silverman J, Zagzag D, Sen R, Wu P, Golfinos JG, Reuss D, Neidert MC et al (2018) Loss of histone H3K27me3 identifies a subset of meningiomas with increased risk of recurrence. Acta Neuropathol 135:955–963. https://doi.org/10.1007/s00401-018-1844-9
Article
CAS
PubMed
Google Scholar
Li HL, Gu XH, Li BJ, Chen X, Lin HR, Xia JH (2017) Characterization and functional analysis of hypoxia-inducible factor HIF1alpha and its inhibitor HIF1alphan in tilapia. PLoS One 12:e0173478. https://doi.org/10.1371/journal.pone.0173478
Article
CAS
PubMed
PubMed Central
Google Scholar
Linsler S, Kraemer D, Driess C, Oertel J, Kammers K, Rahnenfuhrer J, Ketter R, Urbschat S (2014) Molecular biological determinations of meningioma progression and recurrence. PLoS One 9:e94987. https://doi.org/10.1371/journal.pone.0094987
Article
CAS
PubMed
PubMed Central
Google Scholar
Louis DN, Perry A, Reifenberger G, von Deimling A, Figarella-Branger D, Cavenee WK, Ohgaki H, Wiestler OD, Kleihues P, Ellison DW (2016) The 2016 World Health Organization classification of tumors of the central nervous system: a summary. Acta Neuropathol 131:803–820. https://doi.org/10.1007/s00401-016-1545-1
Article
PubMed
Google Scholar
Merico D, Isserlin R, Stueker O, Emili A, Bader GD (2010) Enrichment map: a network-based method for gene-set enrichment visualization and interpretation. PLoS One 5:e13984. https://doi.org/10.1371/journal.pone.0013984
Article
CAS
PubMed
PubMed Central
Google Scholar
Muller II, Melville DB, Tanwar V, Rybski WM, Mukherjee A, Shoemaker MB, Wang WD, Schoenhard JA, Roden DM, Darbar D et al (2013) Functional modeling in zebrafish demonstrates that the atrial-fibrillation-associated gene GREM2 regulates cardiac laterality, cardiomyocyte differentiation and atrial rhythm. Dis Model Mech 6:332–341. https://doi.org/10.1242/dmm.010488
Article
CAS
PubMed
Google Scholar
Mulloy B, Rider CC (2015) The bone morphogenetic proteins and their antagonists. Vitam Horm 99:63–90. https://doi.org/10.1016/bs.vh.2015.06.004
Article
CAS
PubMed
Google Scholar
Nakano A, Harada T, Morikawa S, Kato Y (1990) Expression of leukocyte common antigen (CD45) on various human leukemia/lymphoma cell lines. Acta pathologica japonica 40:107–115
CAS
PubMed
Google Scholar
Nigim F, Wakimoto H, Kasper E, Ackermans L, Temel Y (2018) Emerging medical treatments for meningioma in the molecular era. Biomedicines 6. https://doi.org/10.3390/biomedicines6030086
Article
PubMed Central
Google Scholar
Olar A, Wani KM, Wilson CD, Zadeh G, DeMonte F, Jones DT, Pfister SM, Sulman EP, Aldape KD (2017) Global epigenetic profiling identifies methylation subgroups associated with recurrence-free survival in meningioma. Acta Neuropathol 133:431–444. https://doi.org/10.1007/s00401-017-1678-x
Article
CAS
PubMed
PubMed Central
Google Scholar
Parker M, Mohankumar KM, Punchihewa C, Weinlich R, Dalton JD, Li Y, Lee R, Tatevossian RG, Phoenix TN, Thiruvenkatam R et al (2014) C11orf95-RELA fusions drive oncogenic NF-kappaB signalling in ependymoma. Nature 506:451–455. https://doi.org/10.1038/nature13109
Article
CAS
PubMed
PubMed Central
Google Scholar
Peyre M, Stemmer-Rachamimov A, Clermont-Taranchon E, Quentin S, El-Taraya N, Walczak C, Volk A, Niwa-Kawakita M, Karboul N, Giovannini M et al (2013) Meningioma progression in mice triggered by Nf2 and Cdkn2ab inactivation. Oncogene 32: 4264–4272 Doi https://doi.org/10.1038/onc.2012.436
Article
PubMed
Google Scholar
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L et al (2006) Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell 9:157–173. https://doi.org/10.1016/j.ccr.2006.02.019
Article
CAS
PubMed
Google Scholar
Rogers CL, Perry A, Pugh S, Vogelbaum MA, Brachman D, McMillan W, Jenrette J, Barani I, Shrieve D, Sloan A et al (2016) Pathology concordance levels for meningioma classification and grading in NRG oncology RTOG trial 0539. Neuro-Oncology 18:565–574. https://doi.org/10.1093/neuonc/nov247
Article
PubMed
Google Scholar
Sahm F, Schrimpf D, Stichel D, Jones DTW, Hielscher T, Schefzyk S, Okonechnikov K, Koelsche C, Reuss DE, Capper D et al (2017) DNA methylation-based classification and grading system for meningioma: a multicentre, retrospective analysis. The Lancet Oncol 18:682–694. https://doi.org/10.1016/s1470-2045(17)30155-9
Article
CAS
PubMed
Google Scholar
Sandberg DI, Edgar MA, Resch L, Rutka JT, Becker LE, Souweidane MM (2001) MIB-1 staining index of pediatric meningiomas. Neurosurgery 48:590–595; discussion 595-597
Article
CAS
PubMed
Google Scholar
Schmidt M, Mock A, Jungk C, Sahm F, Ull AT, Warta R, Lamszus K, Gousias K, Ketter R, Roesch S et al (2016) Transcriptomic analysis of aggressive meningiomas identifies PTTG1 and LEPR as prognostic biomarkers independent of WHO grade. Oncotarget 7:14551–14568. https://doi.org/10.18632/oncotarget.7396
Article
PubMed
PubMed Central
Google Scholar
Shaik S, Kennis B, Maegawa S, Schadler K, Yanwen Y, Callegari K, Lulla RR, Goldman S, Nazarian J, Rajaram V et al (2018) REST upregulates gremlin to modulate diffuse intrinsic pontine glioma vasculature. Oncotarget 9:5233–5250. https://doi.org/10.18632/oncotarget.23750
Article
PubMed
Google Scholar
Smith MJ (2015) Germline and somatic mutations in meningiomas. Cancer Genet 208:107–114. https://doi.org/10.1016/j.cancergen.2015.02.003
Article
CAS
PubMed
Google Scholar
Subramanian et al (2005). PNAS, https://www.ncbi.nlm.nih.gov/pubmed/?term=Gene+set+enrichment+analysis%3A+A+knowledge-based+approach+for+interpreting+genome-wide+expression+profiles. https://doi.org/10.1073/pnas.0506580102
Article
CAS
Google Scholar
Sudo S, Avsian-Kretchmer O, Wang LS, Hsueh AJ (2004) Protein related to DAN and cerberus is a bone morphogenetic protein antagonist that participates in ovarian paracrine regulation. J Biol Chem 279:23134–23141. https://doi.org/10.1074/jbc.M402376200
Article
CAS
PubMed
Google Scholar
Thorenoor N, Slaby O (2015) Small nucleolar RNAs functioning and potential roles in cancer. Tumour Biol 36:41–53. https://doi.org/10.1007/s13277-014-2818-8
Article
CAS
PubMed
Google Scholar
Vasudevan HN, Braunstein SE, Phillips JJ, Pekmezci M, Tomlin BA, Wu A, Reis GF, Magill ST, Zhang J, Feng FY et al (2018) Comprehensive molecular profiling identifies FOXM1 as a key transcription factor for meningioma proliferation. Cell Rep 22:3672–3683. https://doi.org/10.1016/j.celrep.2018.03.013
Article
CAS
PubMed
PubMed Central
Google Scholar
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP et al (2010) Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDGFRA, IDH1, EGFR, and NF1. Cancer Cell 17:98–110. https://doi.org/10.1016/j.ccr.2009.12.020
Article
CAS
PubMed
PubMed Central
Google Scholar
Vogel P, Liu J, Platt KA, Read RW, Thiel M, Vance RB, Brommage R (2015) Malformation of incisor teeth in Grem2(−)/(−) mice. Vet Pathol 52:224–229. https://doi.org/10.1177/0300985814528218
Article
CAS
PubMed
Google Scholar
Williams GT, Farzaneh F (2012) Are snoRNAs and snoRNA host genes new players in cancer? Nat Rev Cancer 12:84–88. https://doi.org/10.1038/nrc3195
Article
CAS
PubMed
Google Scholar
Zhou F, Liu Y, Rohde C, Pauli C, Gerloff D, Kohn M, Misiak D, Baumer N, Cui C, Gollner S et al (2017) AML1-ETO requires enhanced C/D box snoRNA/RNP formation to induce self-renewal and leukaemia. Nat Cell Biol 19:844–855. https://doi.org/10.1038/ncb3563
Article
CAS
PubMed
Google Scholar