Skip to main content
Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Sleep fragmentation affects glymphatic system through the different expression of AQP4 in wild type and 5xFAD mouse models

Fig. 6

A Representative images of immunohistochemistry of GFAP and 6e10 antibodies in all the regions analyzed. B Representative images of immunohistochemistry of GFAP and 6e10 antibodies acquired with Axioscan microscope. Scale bar 1000 μm. C Histogram of GFAP and 6e10 shown together. D Histogram of GFAP density analyzed through the percentage of pixels, after the same threshold is set for all the region of interests. NF not fragmented mice, F fragmented mice, LS lateral septum, RSC retrosplenial cortex, MSC motor-sensory cortex, DG dentate gyrus, TH thalamus, HY hypothalamus, BLA basolateral amygdala. The data are mean standard error of the mean (SEM). Each data point represents an individual animal. **p < 0.01; ****p < 0.0001 versus control by ANOVA followed by Bonferroni post-hoc test, n = 4 per condition

Back to article page