Skip to main content
Download PDF

Correction to: Mical modulates Tau toxicity via cysteine oxidation in vivo

Acta Neuropathologica Communications volume 10, Article number: 63 (2022) Cite this article

The Original Article was published on 04 April 2022

Correction to: Acta Neuropathologica Communications (2022) 10:44 https://doi.org/10.1186/s40478-022-01348-1

Following publication of the original article [1], it was noted that due to a typesetting mistake, incorrect files for Additional files 6 and 7 were processed.

The correct files for Additional files 6 and 7 are attached to this Correction and have been corrected in the original article. The publisher apologises to the authors and readers for the inconvenience caused by this error.

Reference

  1. Prifti et al (2022) Mical modulates Tau toxicity via cysteine oxidation in vivo. Acta Neuropathol Commun 10:44. https://doi.org/10.1186/s40478-022-01348-1

    Article  PubMed  PubMed Central  Google Scholar 

Download references

Author information

Author notes

  1. Engie Prifti, Eleni N. Tsakiri and Ergina Vourkou have contributed equally to this work

Authors and Affiliations

  1. Institute for Fundamental Biomedical Research, Biomedical Sciences Research Centre “Alexander Fleming”, 34 Fleming Street, 16672, Vari, Greece

    Engie Prifti, Eleni N. Tsakiri, Ergina Vourkou, Efthimios M. C. Skoulakis & Katerina Papanikolopoulou

  2. Institute for Bio-Innovation, Biomedical Sciences Research Centre “Alexander Fleming”, 34 Fleming Street, 16672, Vari, Greece

    George Stamatakis & Martina Samiotaki

  3. Laboratory of Genetics, Department of Biotechnology, Agricultural University of Athens, Iera Odos 75, 11855, Athens, Greece

    Engie Prifti

Authors
  1. Engie Prifti
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Eleni N. Tsakiri
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Ergina Vourkou
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. George Stamatakis
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Martina Samiotaki
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Efthimios M. C. Skoulakis
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Katerina Papanikolopoulou
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Katerina Papanikolopoulou.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Supplementary Information

Additional file 6: Fig. S5

Targeted proteomics to quantify cysteine oxidation. a Extracted chromatograms for the parent ions and isotopes (upper panel) and of its 6 most abundant fragments (daughter ions, lower panel) at the retention time 27.9 min of the NEM and carbamidomethyl labeled 322CGSLGNIHHKPGGGQVEVK peptide from representative samples of Tau and Tau co-overexpressed with Mical. b Spectra of the scan used for the library creation of the NEM (+ 125 Da) and carbamidomethyl (+ 57 Da) modified 322CGSLGNIHHKPGGGQVEVK peptide.

Additional file 7: Fig. S6 a

Representative Western blot of head lysates from flies expressing UAS-htauFLAG−2N4RC322A using elavC155-GAL4;Ras2-GAL4 and UAS-htauFLAG−2N4RC291A using elavC155-GAL4. Star indicates significant differences between the two groups. b Virgin elavC155-GAL4;Ras2-GAL4 females were crossed with UAS-Mic/CyO and UAS-Mic/CyO;UAS-C322A males. Bars represent the mean number of non-CyO bearing progeny over CyO flies ± SEM of the indicated genotypes. c Response of flies expressing UAS-htauFLAG−2N4RC291A upon treatment with paraquat for 28 h. Star indicates significant difference from the transgene without Mical overexpression. Control flies are elavC155-GAL4/+ (grey bar) and Mical are flies that overexpress Mical under the panneuronal driver (black bar). d Memory performance of animals expressing panneuronally the htauFLAG−2N4RC291A transgene (dark grey bar), compared with the same transgene upon co-expression with Mical (black bar). Star indicates significant difference between the two genotypes. Control flies (light grey bars) are driver elavC155-GAL4/+ flies (CN) and flies that overexpress Mical. The number of experimental replicates (n) is indicated within the bars.

Rights and permissions

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Prifti, E., Tsakiri, E.N., Vourkou, E. et al. Correction to: Mical modulates Tau toxicity via cysteine oxidation in vivo. acta neuropathol commun 10, 63 (2022). https://doi.org/10.1186/s40478-022-01369-w

Download citation

  • Published:

  • DOI: https://doi.org/10.1186/s40478-022-01369-w

Acta Neuropathologica Communications

ISSN: 2051-5960

Contact us