Fig. 5
From: Defining tumor-associated vascular heterogeneity in pediatric high-grade and diffuse midline gliomas
Mural cell coverage and BBB associated marker expression differences between pHGG and DMG mouse models. Representative immunofluorescent z-stack projection images of a Desmin and CD31, b Collagen IV and CD31, and c Plvap and Glut1 in each experimental condition. Scale bar = 20 μm. d, e Quantification of CD31-positive vessel coverage by desmin and collagen IV respectively. f Quantification of Plvap-positive area in Glut1-positive blood vessels in each condition. Data are presented as mean ± SEM. n = 3 for all conditions. *p < 0.05, **p < 0.001, ***p < 0.0001; unpaired t-test with Mann Whitney posthoc comparison