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Table 3 Surgery finding and inflammatory features of teratomas in patients with anti-NMDARE

From: Co-expression of NMDA-receptor subunits NR1, NR2A, and NR2B in dysplastic neurons of teratomas in patients with paraneoplastic NMDA-receptor-encephalitis: a retrospective clinico-pathology study of 159 patients

Group Age Sex Pathology findings Location IgG CD20 CD138 CD3 CD4 CD8
N1 19 f 2.2 × 4.9 × 5.7 cm Cystic mature teratoma Left ovary + ++ + +
N2 18 f 4.7 × 5 × 6.8cmCystic mature teratoma thoracic cavity +++ +++ +++ ++ +
N3 17 f 3 × 3 × 2 cm Cystic mature teratoma Left ovary ++ ++ + +
N4 17 f Cystic mature teratoma Right ovary ++ + ++ ++ ++
N5 28 f 2.1 × 2 × 1.9 cm Cystic mature teratoma Right ovary +++ +
N6 20 f 3.7 × 3 × 2.9 cm Cystic mature teratoma Left ovary +++ +++ +
N7 22 f 1.5 × 1.2 × 1.6 cm Cystic mature teratoma Left ovary ++ ++ ++
N8 20 f 4 × 3 × 1.1 cm Cystic mature teratoma Left ovary ++ ++ + ++ +
N9 29 f Cystic mature teratoma Left ovary +++ + +
N10 35 f 6.8 × 5.4 × 4.5 cm Immature teratoma (WHO III) Left ovary ++ ++ + +
N11 43 f 18.5 × 10.3 × 9 cm Immature teratoma (WHO III) Left ovary +++ +++ + +
N12 25 m 6.7 × 5 × 5.4 cm Mixed germ cell tumor (choriocarcinoma with teratoma) Mediastinum +++ +++ ++ + +++ +
  1. N, patients with paraneoplastic anti-NMDARE; f female, m male, IgG immunoglobulin, Cellular infiltrates: -, negative or positive cells less than 1% of microscopic field; +, < 25%; ++, 25–50%; +++, 50–75%; ++++, > 75%. positive IgG deposit: -, absent; +, mild; ++, moderate; +++ intense