Fig. 1
From: GFAP canonical transcript may not be suitable for the diagnosis of adult-onset Alexander disease
a Severe atrophic changes of the medulla including the inferior olivary nuclei. Moderate cerebellar atrophy. b Linear symmetric abnormal T2 signal predominantly along the anteriolateral aspect of the medulla and a thin zone of abnormal T2 signal about the periphery of the midbrain. c Sagittal view showing atrophy of the brainstem and upper cervical cord. No changes were noted in the subcortical regions