Fig. 2
Diabetic rats show deficits in odour detection and olfactory memory. a Mean sniffing time of wooden blocks covered with a scent of the tested rat (blocks A-C) and unknown rat (block E) in the block test. *comparison of time spent sniffing block E between non-diabetic Wistar and T2D GK rats done by the Mann-Whitney U-test; ∆comparison of time spent sniffing block E with other blocks done by the Wilcoxon Signed Rank test. b Mean sniffing time of the scented cartridge covered with vanilla (odour 1) and lemon (odour 2) in the habituation-dishabituation test. Two-way ANOVA followed by Sidak’s multiple comparisons test. c Mean time to find pellet in the buried pellet test. Mann-Whitney U-test. d Mean sniffing time of the scented cartridge (vanilla/lemon) during 7 trials of the habituation-dishabituation test. Habituation was determined as significant difference in sniffing time between the first and last presentation of the same odour. ∆comparision of sniffing time of odour 1 between T1 and T6. Dishabituation was determined as significant difference between the last presentation of an odour and the first presentation of an alternative odour. φcomparision of sniffing time between T6 (odour 1) and T7 (odour 2). Repeated measures One-way ANOVA followed by Bonferroni’s test. e Mean time to find pellet in buried pellet test performed during 5 consecutive days. Repeated measures One-way ANOVA with Greenhouse-Geisser correction followed by Bonferoni’s multiple comparisons test. The data are means ±S.E.M., *, ∆p < 0.05, **, ∆∆, φφp < 0.01, ***, Δ∆Δ, φφφp < 0.001, **** p < 0.0001