Table 4 Pairwise comparisons among cohorts for each of the vascular outcome measures. The odds ratio (OR) of a higher-level finding was compared among cohorts. Estimated odds used cumulative logistic regression to model the chance of higher-versus-lower severity outcome based on an indicator of the cohort. For arteriolosclerosis, only the AD versus Ctrl comparison could be reliably estimated
From: Cerebrovascular pathology in Down syndrome and Alzheimer disease
Odds Ratios (OR) among Cohorts | |||
|---|---|---|---|
Vascular finding | Est. (95% CI) | P-value | df |
Atherosclerosis | |||
 AD vs Ctrl | 0.46 (0.22, 0.95) | 0.0353 | 140 |
 AD vs Ctrl | 0.46 (0.22, 0.95) | 0.0353 | 140 |
 DS vs Ctrl | 0.11 (0.04, 0.30) | < 0.0001 | 140 |
 DS vs AD | 0.23 (0.09, 0.59) | 0.0026 | 140 |
Arteriolosclerosis | |||
 AD vs Ctrl | 1.08 (0.51, 2.32) | 0.8376 | 142 |
CAA | |||
 AD vs Ctrl | 10.12 (3.94, 25.96) | < 0.0001 | 142 |
 DS vs Ctrl | 30.88 (10.15, 93.99) | < 0.0001 | 142 |
 DS vs AD | 3.05 (1.40, 6.67) | 0.0055 | 142 |