Fig. 5
From: Revisiting rodent models: Octodon degus as Alzheimer’s disease model?
Comparison of neuropathological changes in wild-type degus, wild-type and transgenic mice. While aged wild-type degus (a, 5 years old) and mice (b, 200-days-old) exhibit no sign of β-amyloid deposition, APP/PS1 transgenic mice present with obvious cortical amyloidosis (c, 150-days-old). Compared to wild-type degus (d, g) and mice (e, h), transgenic mice manifest with pronounced micro- (f) and astrogliosis (i). Scale bars = 200 μm