Table 1 Attack rate (AR), hit rate (HR) and incubation period (IP) of scrapie/BSE mixtures inoculated in three wild type mouse lines
Mouse line | Bioassay parameters | Inoculum | |||||
|---|---|---|---|---|---|---|---|
100% scrapie | 1% BSE | 2% BSE | 10% BSE | 50% BSE | 100% BSE | ||
RIII | AR | 0.95 | 0.95 | 0.80 | 0.95 | 0.80 | 0.80 |
HR | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.94 | |
IP | 459 ± 17 | 457 ± 17 | 461 ± 17 | 458 ± 15 | 473 ± 17 | 424 ± 52 | |
C57 | AR | 0.90 | 0.95 | 0.85 | 0.90 | 0.95 | 0.75 |
HR | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 0.88 | |
IP | 464 ± 34 | 481 ± 22 | 448 ± 48 | 485 ± 24 | 491 ± 36 | 595 ± 77 | |
VM | AR | 0.90 | 1.00 | 1.00 | 0.95 | 1.00 | 1.00 |
HR | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | 1.00 | |
IP | 579 ± 86 | 635 ± 85 | 635 ± 62 | 666 ± 61 | 629 ± 100 | 638 ± 64 | |