Figure 6
Expression of MARK4 and p-tau Ser 262 in hippocampi with increasing neurofibrillary pathology. Photomicrographs of exactly adjacent sections from the CA1-CA2 field of three cases (#6, #31 and #29) with increasing degree of neurofibrillary pathology, stained with MARK4 and p-tau Ser262 antibodies. Arrowheads indicate neurons that stain positive for MARK4, which increase with Braak stage. Those neurons in the adjacent section are also intensely stained with the p-tau Ser262 antibody. Scale bar: 50 μm.