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Table 2 CIS gene expression according to clinicogenetic groups and presence of metastatic disease

From: Identification of a neuronal transcription factor network involved in medulloblastoma development

Clinicogenetic groups   Metastatic disease
   SHH v Other Subgroups   WNT (N=15) SHH (N=24) Group 3 (N=24) Group 4 (N=48)   Mets (N=32) No Mets (n=75)  
   Mean SHH Mean others t p-val Mean   SE Mean   SE Mean   SE Mean   SE p-val Mean   SE Mean   SE p-val
NFIA 22497_at 11.25 10.80 -1.31   11.41 ± 0.18 11.25 ± 0.30 9.44 ± 0.42 11.32 ± 0.16 ** 10.78 ± 0.32 11.03 ± 0.15  
ATXN2 202622_s_at 7.41 7.60 2.00   7.50 ± 0.11 7.41 ± 0.08 7.36. ± 0.11 7.75 ± 0.06 ** 7.68 ± 0.08 7.47 ± 0.05 *
TEAD1 224955_at 10.80 9.85 -6.34 ** 11.10 ± 0.12 10.80 ± 0.12 10.13 ± 0.15 9.33 ± 0.07 ** 9.68 ± 0.13 10.11 ± 0.11 *
TGIF2 216262_s_at 7.61 5.02 -8.98 *** 7.75 ± 0.10 7.61 ± 0.23 5.48 ± 0.28 3.97 ± 0.10 ** 4.46 ± 0.22 5.88 ± 0.22 ***
CREBBP 202160_at 9.93 9.80 -0.85   9.95 ± 0.10 9.93 ± 0.10 9.13 ± 0.32 10.09 ± 0.07 ** 9.76 ± 0.13 9.82 ± 0.12  
DSCR3 203635_at 7.08 6.78 -3.19 ** 6.84 ± 0.18 7.08 ± 0.08 6.69 ± 0.09 6.80 ± 0.06 ** 6.82 ± 0.08 6.82 ± 0.06  
PTEN 225363_at 10.31 11.12 4.63 *** 11.16 ± 0.20 10.31 ± 0.15 10.12 ± 0.15 11.62 ± 0.06 ** 11.03 ± 0.14 10.94 ± 0.10  
ITGBL1 214927_at 6.49 3.90 -4.47 *** 4.27 ± 0.56 6.49 ± 0.55 3.16 ± 0.25 4.16 ± 0.25 ** 3.91 ± 0.33 4.85 ± 0.27 *
NFIB 209290_s_at 12.92 12.67 -0.66   10.46 ± 0.48 12.92 ± 0.32 12.18 ± 0.38 13.58 ± 0.09 ** 12.81 ± 0.28 12.85 ± 0.16  
MYT1L 210016_at 8.27 10.24 2.80 ** 6.06 ± 0.70 8.27 ± 0.64 9.20 ± 0.43 12.02 ± 0.11 ** 11.28 ± 0.22 9.41 ± 0.36 **
ANKRD5 220144_s_at 4.63 4.75 0.54   4.51 ± 0.28 4.63 ± 0.19 5.46 ± 0.21 4.46 ± 0.10 ** 4.65 ± 0.16 4.77 ± 0.11  
SLIT3 203813_s_at 3.01 2.98 -0.17   2.90 ± 0.09 3.01 ± 0.14 2.82 ± 0.05 3.09 ± 0.10   2.98 ± 0.10 2.94 ± 0.06  
TMEM45B 226226_at 2.37 2.44 1.57   2.34 ± 0.04 2.37 ± 0.04 2.52 ± 0.04 2.44 ± 0.03 * 2.45 ± 0.03 2.44 ± 0.02  
SFI1 36545_s_ar 5.96 5.19 -2.68   5.74 ± 0.24 5.96 ± 0.25 4.42 ± 0.23 5.42 ± 0.19 ** 5.24 ± 0.20 5.36 ± 0.16  
FGF13 205110_s_at 5.88 8.10 6.66 * 5.33 ± 0.86 5.88 ± 0.54 6.81 ± 0.49 9.58 ± 0.16 ** 8.73 ± 0.39 7.01 ± 0.32 **
L3MBTL4 228557_at 6.85 3.73 -7.43 *** 4.28 ± 0.28 6.85 ± 0.40 4.82 ± 0.22 3.01 ± 0.10 ** 3.76 ± 0.21 4.59 ± 0.24 *
ADCY5 228182_at 3.50 3.70 0.66 *** 3.52 ± 0.27 3.50 ± 0.27 2.73 ± 0.16 4.25 ± 0.21 ** 3.65 ± 0.22 3.60 ± 0.16  
  1. Genes and associated Affymetrix probe IDs are shown. All values are mean log2 expression levels from [38] and [39]. Standard errors (SE) are shown. SHH v Other Subgroups, and presence/absence of metastatic disease, were analysed using t-tests. Clinicogenetic groups [2] were analysed using ANOVA. *p<0.05, **p<0.01, ***p<0.001.