Figure 4
From: Identification of a neuronal transcription factor network involved in medulloblastoma development
Network activity correlates with tumour subgroup, metastasis and survival. a. Gene expression heatmaps of CIS genes and network genes with enriched ontologies in all 4 clinicogenetic subgroups are shown. Where more than one probe per gene was present in the network, the probe with the highest mean expression level across all samples is shown. b. Box and whisker plot showing log of metagene expression in MB clinicogenetic subgroups. ANOVA p-value is shown. Boxes represent the 25th to 75th percentile, with median values shown as solid lines. Whiskers represent 95th percentile, and outliers are shown individually. c. Log of metagene expression in tumours with metastases and those without. T-test p-value is shown. d. Kaplan Meier curve of SHH subgroup tumours relative to Metagene score.