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Table 3 Overview of sample and ROI selection for spatial profiling with NanoString GeoMx®

From: Disease and brain region specific immune response profiles in neurodegenerative diseases with pure and mixed protein pathologies

Region

Panel

# Scans/Samples

# ROIs

ROI labels

Disease background

FC

Parkinson’s morphology

23

182

noLB, LB

3 Control, 8 MIX, 4 AD, 8 LBD

MB

Parkinson’s morphology

20

226

noLB, LB

3 Control, 8 MIX, 9 LBD

FC

Alzheimer’s and Parkinson’s morphology

12

192

Plaque, Plaque with LB, noLB, LB

4 Control, 4 AD, 4 MIX