Fig. 7From: Dysregulation of neuroprotective lipoxin pathway in astrocytes in response to cytokines and ocular hypertensionEffect of LXB4 treatment on lipoxin pathway in human brain astrocytes. (A) Astrocyte reactivity genes analyzed by qPCR. The results were normalized to GAPDH. Data are presented as the mean ± SEM, n = 3–4. (B) Representative immunofluorescence images of LCN2 and 5-LOX. Nuclei were labeled with DAPI. (C) LC‒MS/MS-based lipidomic quantification of endogenous lipid mediators, n = 4–5. (Ctrl-untreated control astrocytes, RA- reactive astrocytes). *p < 0.05, **p < 0.01, ***p < 0.001Back to article page