Fig. 6

UMAP dimension reduction reveals an alternative microarray quality assessment parameter for methylation data: Abnormal methylation microarray signatures cluster in pan-cancer UMAP plots. Such datasets were annotated as DNADEG. Incoming samples having mostly DNADEG-annotated reference cases within their 15 nearest neighbours should be excluded from data interpretation. The inset (upper left) reveals a tight clustering of DNADEG cases. The red box is an example of a pop-up-on-mouse-hover annotation, revealing at a glance the microarray ID and annotation for each dot in the plot