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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Chronic hypoxia remodels the tumor microenvironment to support glioma stem cell growth

Fig. 4

Receptor ligand modelling uncovers astrocyte expression of candidate pro-tumorigenic ligands. a Heatmap showing the total number of interactions between cell types in ltGLICO dataset obtained with CellPhoneDB. b Circos plot showing interaction between ligands secreted by organoid cell types and receptors expressed by 320-GSCs. c Violin plot showing expression of oxidative stress associated ligands (SPP1, PDGFA, FGF1, FGF2) in glial cells

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