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Fig. 5 | Acta Neuropathologica Communications

Fig. 5

From: Human adipose tissue-derived stem cell extracellular vesicles attenuate ocular hypertension-induced retinal ganglion cell damage by inhibiting microglia- TLR4/MAPK/NF-κB proinflammatory cascade signaling

Fig. 5

ADSC-EVs prevent further RGC and axon loss in OHT mice 2 weeks after injection. (A) Representative retinal immunostaining and quantification of the RBPMS+ RGCs (n = 8, *p < 0.05, **p < 0.01). (B) Representative optic nerve semithin transverse sections and quantification of axons (n = 3, *p < 0.05, ***p < 0.001)

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