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Fig. 4 | Acta Neuropathologica Communications

Fig. 4

From: Organelle resolved proteomics uncovers PLA2R1 as a novel cell surface marker required for chordoma growth

Fig. 4

Validation of PLA2R1 in clinical samples. a Testing the expression of PLA2R1 in chordoma cell lines (U-CH17M, U-CH17S and U-CH11R), chordoma tissues and commercially available normal tissue lysates by immunoblots. b The variability of PLA2R1 expression among tumor samples grouped into an upper tertile and lower two-thirds of expression for visualization. c Kaplan Meier plot showing poorer PFI in the top third of patients according to percent of cells positive for PLA2R1 by IHC. d Kaplan Meier plot showing that increased PLA2R1% positivity is associated with poorer OS

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