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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: Astrocytic accumulation of tau fibrils isolated from Alzheimer’s disease brains induces inflammation, cell-to-cell propagation and neuronal impairment

Fig. 3

Astrocyte-to-astrocyte transfer of AD tau fibrils through tunneling nanotubes (TNTs). Time-lapse microscopy of Amytracker-labelled AD tau fibrils (shown in red) demonstrating direct cell-to-cell transmission between human astrocytes through TNTs. The presented images were captured with six-minute intervals. Arrowheads indicate a tau aggregate travelling from a projection of one astrocyte to the cell body of another. Scale bar = 25 μm

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