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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: CNS embryonal tumour with concomitant novel BRD4::CTRC1 fusion and BCOR internal tandem duplication – evidence for synergism and non-mutually exclusive alterations in CNS embryonal tumours

Fig. 2

Histopathological features. (a) Tumour cells arranged in large nests (HE, magnification 40x). (b) Trabecular arrangement (HE, magnification 200x). (c) Tumour cells with ample cytoplasm (HE, magnification 400x). (d) Tumour cells showing H3K27me3 loss with retained expression in normal elements (magnification 200x) (e) Tumour cells showing diffuse and strong BCOR positivity with absent staining in normal elements (magnification 200x). (f) Ki67 index of the tumour cells is markedly elevated (> 90%) (magnification 200x). HE, hematoxylin-eosin

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