Fig. 9

Gnao1 deficiency in SCs result in the activation of PI3K-AKT cascade, contributing to SC differentiation. A WB analysis of the activation of PI3K/AKT and MAPK/ERK in the in vitro SC differentiation model, also shown are representative WB images (left) and quantitative statistics (right). T-test, n = 3, Ns, p > 0.05 vs control, no statistical difference. *, p < 0.05 and **, p < 0.01 vs control. B WB analysis of the activation of PI3K/AKT and MAPK/ERK in differentiated Gnao1-KD-SCs (Gnao1-shRNA) and control SCs (Scramble), also shown are representative WB images (left) and quantitative statistics (right). T-test, n = 3, Ns, p > 0.05 vs control, no statistical difference. **, p < 0.01 vs Scramble