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Fig. 3 | Acta Neuropathologica Communications

Fig. 3

From: MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects

Fig. 3

MANF is expressed in CD68 + cells in the ischemic cortex and ipsilateral thalamus. Double immunofluorescence staining of rat brain paraffin sections 2 (a, b, c) and 14 (d) days after 90-min dMCAo. NeuN and MANF colocalize in the contralateral (a) but not in the ischemic cortex (b). CD68 and MANF colocalize in the peri-infarct area (c) and in the ipsilateral thalamus (d). Scale bar is 10 µm

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