Fig. 1

MANF protein expression correlates with CD68 expression at 2 weeks after ischemic stroke in the human brain. Anti-MANF and anti-CD68 immunostaining of human cerebral tissue from ischemic stroke patients at 3d, 1wk and 2wk post-stroke. The patient and sample details are shown in Table 2. a-f Contralateral hemisphere of the ischemic brain (a, b Patient 1, frontal region; c, d Patient 4, frontal region; e, f Patient 7, parietal region) g-l The ischemic core (g, h Patient 1, pons; i, j Patient 4, frontal region; k, l Patient 7, parietal region. Scale bar is 1000 µm and 50 µm. Location of high magnification images indicated in the whole section images