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Table 3 Patient characteristics in relation to age interval

From: Cortical microvascular raspberries and ageing: an independent but not exclusive relationship

Age interval

20–29

30–39

40–49

50–59

60–69

70–79

80–89

90–99

Total

n

9

14

23

37

32

100

37

11

263

Female sex

4/9 (44%)

6/14 (43%)

10/23 (43%)

12/37 (32%)

12/32 (38%)

27/100 (27%)

11/37 (30%)

1/11 (9%)

83/263 (32%)

Median brain weight

1270 g

1430 g

1400 g

1410 g

1343 g

1303 g

1269 g

1273 g

1320 g

ADNC

0/9 (0%)

0/14 (0%)

1/23 (4%)

0/37 (0%)

3/32 (9%)

7/100 (7%)

6/37 (16%)

4/11 (36%)

21/263 (8%)

LBD or MSA

0/9 (0%)

0/14 (0%)

0/23 (0%)

4/37 (11%)

3/32 (9%)

12/100 (12%)

1/37 (3%)

0/11 (0%)

21/263 (8%)

FTLD

0/9 (0%)

0/14 (0%)

0/23 (0%)

4/37 (11%)

4/32 (13%)

17/100 (17%)

4/37 (11%)

0/11 (0%)

29/263 (11%)

VCI

0/9 (0%)

0/14 (0%)

0/23 (0%)

1/37 (3%)

1/32 (3%)

10/100 (10%)

5/37 (14%)

3/11 (27%)

21/263 (8%)

Mixed/other NDD

0/9 (0%)

0/14 (0%)

0/23 (0%)

0/37 (0%)

5/32 (16%)

20/100 (20%)

13/37 (35%)

3/11 (27%)

41/263 (16%)

NDD and VCI, total

0/9 (0%)

0/14 (0%)

1/23 (4%)

9/37 (24%)

16/32 (50%)

66/100 (66%)

29/37 (78%)

10/11 (91%)

131/263 (50%)

CVI, one

0/9 (0%)

1/14 (7%)

3/23 (13%)

3/36 (8%)

2/31 (6%)

15/97 (15%)

6/35 (17%)

4/11 (36%)

34/256 (13%)

CVI, multiple

2/9 (22%)

0/14 (0%)

1/23 (4%)

5/36 (14%)

14/31 (45%)

34/97 (35%)

14/35 (40%)

5/11 (45%)

75/256 (29%)

CVI, total

2/9 (22%)

1/14 (7%)

4/23 (17%)

8/36 (22%)

16/31 (52%)

49/97 (51%)

20/35 (57%)

9/11 (82%)

109/256 (43%)

C-ASCL

0/8 (0%)

0/12 (0%)

3/21 (14%)

6/35 (17%)

12/32 (38%)

57/97 (59%)

20/37 (54%)

7/11 (64%)

105/253 (42%)

C-SVD

0/9 (0%)

0/14 (0%)

6/22 (27%)

10/37 (27%)

10/32 (31%)

47/97 (48%)

22/36 (61%)

4/10 (40%)

99/257 (39%)

Cardiac hypertrophy

0/5 (0%)

0/7 (0%)

5/14 (36%)

6/19 (32%)

14/30 (47%)

39/94 (41%)

16/36 (44%)

6/10 (60%)

86/215 (40%)

Nephrosclerosis

0/7 (0%)

0/10 (0%)

2/18 (11%)

2/31 (6%)

8/31 (26%)

51/100 (51%)

23/37 (62%)

8/11 (73%)

94/245 (38%)

HT, no organ damage

0/9 (0%)

0/13 (0%)

2/21 (10%)

4/37 (11%)

11/31 (35%)

31/89 (35%)

12/37 (32%)

3/9 (33%)

63/246 (26%)

HT, organ damage

0/9 (0%)

0/13 (0%)

2/21 (10%)

2/37 (5%)

6/31 (19%)

19/89 (21%)

10/37 (27%)

2/9 (22%)

41/246 (17%)

HT, unclassified

0/9 (0%)

0/13 (0%)

1/21 (5%)

6/37 (16%)

0/31 (0%)

5/89 (6%)

1/37 (3%)

0/9 (0%)

13/246 (5%)

HT, total

0/9 (0%)

0/13 (0%)

5/21 (24%)

12/37 (32%)

17/31 (55%)

55/89 (62%)

23/37 (62%)

5/9 (56%)

117/246 (48%)

Diabetes mellitus

0/9 (0%)

0/13 (0%)

5/23 (22%)

6/37 (16%)

9/29 (31%)

21/90 (23%)

10/36 (28%)

3/11 (27%)

54/248 (22%)

Other findings*

4/9 (44%)

3/14 (21%)

6/23 (26%)

7/37 (19%)

1/32 (3%)

7/100 (7%)

1/37 (3%)

0/11 (0%)

29/263 (11%)

  1. *Neuropathological findings not included in the statistical analyses: demyelinating disease (n = 6), malformation (n = 3), malignancy (n = 5), toxic disease (n = 5), traumatic injury (n = 3), other/unclassified (n = 7). ADNC Alzheimer's disease neuropathologic change; LBD Lewy body disease; MSA multiple system atrophy; VCI vascular cognitive impairment; NDD neurodegenerative disease; CVI cerebral infarct; C-ASCL cerebral atherosclerosis; C-SVD cerebral small vessel disease; HT hypertension