Table 4 GO-Terms and associated transcripts differentially expressed in striatal astrocytes of MBP29-hα-syn mice
From: Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy
Pathway | Genes |
|---|---|
Actin binding | ARPC1B, MSN |
Cell cycle | CDKN1A |
Cytokines | CCL2, CLCF1, CXCL2, IL6, SPP1 |
Extracellular matrix | CELA1, ECM1, ICAM1, IGFBP3, OLFML3, PVR |
Growth factors | GDF15 |
Interferon-γ response | GBP3, IFI202B |
Immune response | TLR4, CD14 |
Lipid homeostasis | CH25H, PLA2G4A |
Membrane regulation | ANXA3 |
Metabolic processes | ASPG, OASL2, PDE3B |
Metal ion | SLC39A14 ↓ |
Miscellaneous | AHNAK2, BTG3, IER3, LRRFIP1, SLC7A1, TSPAN4 |
Neuronal activity | GAP43, SYT4 |
Oxidative stress | GPX1 |
Peptidase activity/inhibition | LONRF1, USP18, SERPINE1, SERPING1 |
Signaling transduction/receptors | GADD45B, IL13RA1, TNFRSF12A |
Structural proteins | GFAP, TUBB6 |
Transcription factors | BCL3, SBNO2, TGIF1 |
Zinc binding | RNF19B |