Table 2 Overview of astrocytic proteins involved in CNS homeostasis and their associated functions
From: Distinct forebrain regions define a dichotomous astrocytic profile in multiple system atrophy
Protein | Function |
|---|---|
Aquaporin-4 (AQP4) | CNS water homeostasis |
Glial fibrillary acidic protein (GFAP) | Intermediate filament of mature astrocytes |
Growth-associated protein 43 (GAP-43) | Regenerative response, microglia activation |
Glutamate transporter 1 (GLT-1) | Synaptic L-glutamate clearance |
Glutamate-aspartate transporter 1 (GLAST) | Termination excitatory neurotransmission |
Glutamine synthetase (GS) | Glutamine synthesis from glutamate |
Vimentin (VIM) | Intermediate filament for cytoskeletal organization |