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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Cerebrospinal fluid shotgun proteomics identifies distinct proteomic patterns in cerebral amyloid angiopathy rodent models and human patients

Fig. 2

Volcano plots of differentially expressed proteins between rTg-DI and WT rats at ages 3M (A), 6M (B) an 12M (C). The vertical axis displays the -log10 p-value of Wilcoxon signed rank tests before multiple testing correction. The horizontal axis displays the log2 fold change. The red, dotted lines represent the significance level of p = 0.05 (horizontal), and fold-changes of ± 1.25 (vertical). Proteins which are significantly different between groups and exceed the fold-change thresholds are displayed in green (upregulated) and red (downregulated). Proteins which do not exceed the significance or foldchange thresholds are displayed in black

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