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Table 1 Demographics on neuropathology cohorts used

From: Toward a generalizable machine learning workflow for neurodegenerative disease staging with focus on neurofibrillary tangles

 

Cohorts

Emory-Train

Emory-Test

UC Davis

Demographics

Number of cases (M/F)

52 (30/22)

59 (23/36)

23 (12/11)

Average age at death (std. dev.)

70.44 (10.22)

70.83 (14.96)

83.83 (7.32)

Race/ethnicity

Caucasian

42 (80.77%)

48 (81.36%)

18 (78.26%)

Black/African American

10 (19.23%)

7 (11.86%)

1 (4.35%)

Hispanic

2 (8.70%)

Asian

1 (4.35%)

Unknown

4 (6.78%)

1 (4.35%)

Braak NFT Stage

0

1 (1.92%)

4 (6.78%)

I

4 (7.69%)

7 (11.86%)

I–II

2 (3.85%)

II

7 (13.46%)

5 (8.47%)

1 (4.35%)

III

5 (9.62%)

7 (11.86%)

3 (13.04%)

IV

4 (7.69%)

6 (10.17%)

3 (13.04%)

V

7 (13.46%)

4 (6.78%)

5 (21.74%)

VI

22 (42.31%)

26 (44.07%)

11 (47.83%)

Tau antibody (WSI counts)

PHF-1

138 (65.71%)

173 (73.00%)

AT8

23 (10.95%)

28 (11.81%)

92 (100%)

CP13

12 (5.71%)

pan-tau

37 (17.62%)

36 (15.19%)

  1. For each cohort we include the demographics (sex, age at death, and race/ethnicity), the number of cases in each Braak NFT stage, and the distribution of WSI stained with different tau antibodies. The NFT Braak stage is provided for each case during neuropathology assessment.
  2. M male, F female, std. dev. standard deviation