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Table 1 Distribution of clinical and pathological patient characteristics among the included studies

From: CDKN2A/B deletions are strongly associated with meningioma progression: a meta-analysis of individual patient data

Parameters

Sievers et al. [37]

Wang et al. [46]

Driver et al. [6]

Khan et al. [16]

p

Sex

0.45

 Female

350/528

698/1059 (65.9%)

353/527 (67.0%)

NA (only available among those with CDKN2A/B deletions)

 Male

(66.28%)

391/1059 (36.9%)

174/527 (33.0%)

 

178/528 (33.71%)

  

Age (in years)

58.5 (median) (IQR: 48.0–67.0)

NA

57 (mean) (range: 9–90)

NA (only available among those with CDKN2A/B deletions)

 

Extent of resection

   

NA (only available among those with CDKN2A/B deletions)

0.013

 GTR

NA

418/588 (71.1%)

338/527 (64.1%)

 STR

NA

170/588 (28.9%)

189/527 (35.9%)

Location

   

 Skull base

95/528 (18.0%)

NA

NA

NA

 Convexity

308/528 (58.3%)

 Posterior fossa

38/528 (7.2%)

 Spinal

 

 Supratentorial

27/528 (5.1%)

 NA

34/528 (6.4%)

 

24/528 (4.6%)

TERT promoter mutation

6/293 (2.05%)

NA

6/244 (2.46%)

NA (only available among those with CDKN2A/B deletions)

0.75

  1. GTR, gross total resection; IQR, interquartile range; NA, not available; STR, subtotal resection; TERT, telomerase reverse transcriptase