Fig. 5

a Kaplan–Meier chart displaying probability of progression-free survival stratified by the combination of previous 2016 WHO grading combined with CDKN2A/B status (heterozygous, homozygous, and wild-type). B Kaplan–Meier chart displaying probability of progression-free survival stratified by WHO grade 1 or 2 meningiomas with a heterozygous CDKN2A/B deletion (red line) and WHO grade 1, 2 or 3 meningiomas with a CDKN2A/B wild-type status (turquoise line) c Forest plots from multivariable Cox regression analysis: Homozygous or heterozygous CDKN2A/B deletions, male sex, and WHO grade 2 or 3 are independent predictors of progression-free survival. The dashed line represents a hazard ratio of 1.0. p values in italics display statistically significant results. Het, Heterozygous; Hom, Homozygous; WT, Wild-type