Fig. 4

a Forest plot displaying log (hazard ratio), HR, and 95% CI estimates for PFS in a random effect model with the inverse variance method of the included studies [3, 12, 27, 36] evaluating any type (hetero- or homozygous) CDKN2A/B compared with wild-type. Risk of meningioma progression in patients with homozygous CDKN2A/B deletions compared with wild-type is shown in b. c Forest plot displaying the increased risk of meningioma progression in patients with heterozygous CDKN2A/B deletions compared with wild-type. X-axis locations of squares display the hazard ratio. The weight of the included studies is also presented. The diamond corresponds to the hazard ratio of the pooled data. The diamond corresponds to the hazard ratio of the pooled data. Het, Heterozygous; Hom, Homozygous; SE, Standard error; WT, Wild-type