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Fig. 6 | Acta Neuropathologica Communications

Fig. 6

From: Rare germline variants in POLE and POLD1 encoding the catalytic subunits of DNA polymerases ε and δ in glioma families

Fig. 6

Clinical features of 37 brain tumor patients carrying rare POLE or POLD1 germline variants reported in this study or previously (patients and references are listed in the Additional file 1: Table S6). (a) Types of brain tumors observed in patients with rare POLE/POLD1 germline variants. Giant cell glioblastomas are overrepresented. (b) Additional features reported in brain tumor patients with rare POLE/POLD1 germline variants. Gastrointestinal and cutaneous phenotypes are particularly frequent. NOS, not otherwise specified

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Acta Neuropathologica Communications

ISSN: 2051-5960

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