Accurate digital quantification of tau pathology in progressive supranuclear palsy

Table 7 Spearman’s correlation coefficients between tau density and PSP stage

Tau type	All regions	Cortical regions	Subcortical regions
Total tau density	0.37**	0.57**	0.27*
CB + NFT + TA density	0.47**	0.59**	0.39**
CB density	0.46**	0.58**	0.38**
NFT density	0.37**	0.51**	0.24*
TA density	0.37**	0.62**	N/A
TF density	0.36**	0.56**	0.26*

Correlation coefficients are reported when considering all brain regions, only cortical regions, and only subcortical regions. *Correlations significant at P < 0.05, **Correlations are significant at P < 0.001. Not applicable (N/A) as TA density is only quantifiable in putamen. CB coiled body, NFT neurofibrillary tangle, TA tufted astrocyte, TF tau fragments

ISSN: 2051-5960