Model | All regions | Cortical regions | Subcortical regions |
|---|
CB density | 0.69 | 0.29** | 0.47 |
NFT density | 0.82 | 0.29** | 10.52** |
TA density | 0.84 | 0.31** | N/A |
TF density | 0.83 | 1.10 | 0.95 |
- The comparison is made in 3 regional groupings; logarithmic tau density quantified across all brain regions, and separately for cortical and subcortical regions. **Indicates BF > 3 (substantial evidence for tau type-specific density that it correlates better with PSPRS score than total tau density) or BF < 1/3 (substantial evidence for total tau model as compared to tau type-specific model). Where 1/3 < BF < 3, the evidence from the available data is inconclusive. Not applicable (N/A) as TA density is only quantifiable in putamen. PSPRS PSP rating scale. BF Bayes’ factor, CB coiled body, NFT neurofibrillary tangle, TA tufted astrocyte, TF tau fragments
