Fig. 2

Evaluation of immune cell infiltrates in healthy and FSHD muscles. a Representative pictures of peroxidase staining of CD4⁺, CD8⁺, CD20⁺ and BDCA1⁺ cells in healthy, FSHD STIR− and FSHD STIR+ muscle sections (20× magnification). The graphs show the total distribution of CD4⁺ cells/mm² (b) in healthy (n = 6), FSHD STIR− (n = 16) and FSHD STIR+ (n = 15) muscles, CD8⁺ cells/mm² (c) in healthy (n = 6), FSHD STIR− (n = 14) and FSHD STIR+ (n = 15) muscles, CD20⁺ cells/mm² (d) in healthy (n = 6), FSHD STIR− (n = 16) and FSHD STIR+ (n = 15) muscles and BDCA1⁺ cells/mm² (e) in healthy (n = 6), FSHD STIR− (n = 17) and FSHD STIR+ (n = 15) muscles. The results are reported as mean ± SD. Groups were compared using Kruskal–Wallis test (§ < 0.05, §§ < 0.01, §§§p < 0.001) followed by Dunn’s multiple comparison test (*p < 0.05, **p < 0.01, ***p  < 0.001)