Fig. 1

Collagen content of healthy and FSHD muscles. a Representative pictures of picrosirius red staining in healthy, FSHD STIR− and FSHD STIR+ muscle sections (20× magnification). b The graph shows the percentage of fibrosis per field in healthy (n = 12), FSHD STIR− (n = 28) and FSHD STIR+ (n = 27) muscles. The results are reported as mean ± SD and were compared using Kruskal–Wallis test (§§§§p < 0.0001) followed by Dunn’s test (*p < 0.05, ***p < 0.001, ****p < 0.0001). c Pearson correlation between the percentage of fibrosis and the MRI T1-score of sampled FSHD muscles