Fig. 5
From: Cryo-EM structures of tau filaments from the brains of mice transgenic for human mutant P301S Tau
Common structural motif of Tg2541 and PS19 Tau filament folds. a, Superposition of Tau filament folds with a common substructure (N296-K311, sticks). P301S Tau folds from transgenic mouse lines Tg2541 and PS19 are shown in green and blue, whereas the wild-type Tau folds of LNT (PDB:7P6) and 20a (PDB:7QL2) are shown in magenta and yellow, respectively. b, Superposition of the Tg2541 common motif, shown in green, onto the structure of the first intermediate amyloid (FIA) (PDB:8PP0), shown in orange