Fig. 4
From: Determinants of astrocytic pathology in stem cell models of primary tauopathies
hESC-derived astrocytes preferentially take up 4R tau. hESC-derived astrocytes exposed to either labeled recombinant 3R or 4R tau over the course of 24 h exhibit preferential uptake of 4R. Image stills of hESC-derived astrocytes exposed to labeled recombinant 3R or 4R tau (magenta) over the course of 24 h show more 4R in cells than 3R. Scale bar = 200 μm; n = 3 biological replicates per condition