Fig. 3
From: Determinants of astrocytic pathology in stem cell models of primary tauopathies
Validation of cell differentiation. Stem cells show positive staining for OCT3/4 and NANOG (top left), and neuronal precursor cells stain positive for Nestin, SOX1, and PAX6 (top right). Astrocytes show positive staining for S100β and GFAP (bottom left) with little to no DCX (bottom right). A single cell showing neuronal differentiation is indicated by white arrow (bottom right). Scale bars = 200 μm. Individuals panels for each stain are shown in Figs. S1, S2, and S3 for stem cells, neural progenitors, and astrocytes, respectively