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Fig. 2 | Acta Neuropathologica Communications

Fig. 2

From: Determinants of astrocytic pathology in stem cell models of primary tauopathies

Fig. 2

Astrocytes do not upregulate tau mRNA in astrocytic tauopathies. (A) Mean number of mRNA puncta per astrocyte in control, AD, PSP, and CBD. (B) Proportion of tau mRNA positive astrocytes in control, AD, PSP, and CBD. (C) Mean number of puncta comparing tau-positive and negative astrocytes within cases of PSP. (D) Representative low power ROI with insets of tau-positive and negative astrocytes shown in (E) and (F), respectively. Scale bars = 1000 μm in (D) and 20 μm in (E) and (F); n = 3 individual cases per condition in (A) and (B) and n = 4 individual cases in (C)

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