Table 1 Clinical features of pathology-confirmed CTE cases
From: TDP43 pathology in chronic traumatic encephalopathy retinas
No. | Age | Sex | Primary pathologic diagnosis | Cause of death | Athletic history | Position played | No. of concussions | p-TDP43 presence | p-TDP43 positive regions |
|---|---|---|---|---|---|---|---|---|---|
1 | 86 | M | CTE Stage IV | Not available | Semi-professional football | Not available | Not available | Unknown | Unknown |
2 | 80 | M | CTE Stage IV | Respiratory failure | NFL | Running back | 1 (0 LOC) | Yes | Spinal cord, Amygdala, Hippocampus, Entorhinal cortex/Inferior temporal cortex, Neocortex |
3 | 93 | M | CTE Stage IV | Dementia related | Amateur boxing | Not applicable | Unknown | Yes | Spinal cord, Amygdala, Hippocampus, neocortex |
4 | 82 | M | CTE Stage IV | Respiratory failure | NFL | Defensive back, safety, special teams | ~ 100 (unknown LOC) | Yes | Amygdala, hHppocampus, Entorhinal cortex/Inferior temporal cortex |
5 | 77 | M | CTE Stage IV | Cardiac condition | Australian Rugby | Flanker, break-away | “1000 s” (0 LOC) | Yes | Spinal cord, Amygdala, Hippocampus |
6 | 70 | M | CTE Stage IV | Dementia related | “Professional football” | Defensive back, safety | 10 (1 LOC) | Yes | Spinal cord, Amygdala, neocortex |
7 | 62 | M | CTE Stage IV | Cardiac condition | NFL | Defensive back, safety | 25 (1 LOC) | Yes | Amygdala, Hippocampus |
8 | 70 | M | CTE Stage IV | Cardiac condition | NFL, recreational rugby | Offensive lineman | 10 (1 LOC) | Yes | Amygdala, Hippocampus, Entorhinal cortex/Inferior temporal cortex |