Fig. 2From: Molecular profiling of pre- and post-treatment pediatric high-grade astrocytomas reveals acquired increased tumor mutation burden in a subset of recurrencesSummary of two newly-identified pHGG cases with increased TMB at recurrence. Radiologic, histologic, immunohistochemical, and genetic features are summarized. Scale bars for histology = 50 microns. Radiology images are T2-weighted FLAIR for pre-treatment pTMZ-01 and T1-weighted post-contrast for all other imagesBack to article page