Fig. 4
From: Low-intensity open-field blast exposure effects on neurovascular unit ultrastructure in mice
Ultrastructural abnormalities of basement membranes in mouse brains post-LIB exposure. (a) Representative electron micrographs of microvessels in sham controls and LIB-exposed mice. Basement membranes (BM) are highlighted in blue in sham controls and pink in LIB-exposed mice at 7 DPI. Scale bar, 1 μm. (b) Quantifications of electron micrographs reveal basement membrane thickness in sham controls and LIB-exposed mice at 7 and 30 DPI. **, p < 0.01 and ***, p < 0.001. Data are expressed as median and interquartile range. (c) Blue arrows indicate normal basement membrane (BM) structure in sham control mice (c1); red arrows indicate abnormal basement membrane structures in LIB-exposed mice with bulges (c2), fragmentations (c3), corrugations (c4), and vacuoles within basement membranes (c5) at 7 DPI, as well as fragmentations (c6) at 30 DPI. Scale bar, 0.5 μm