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Fig. 8 | Acta Neuropathologica Communications

Fig. 8

From: Selective neuroimmune modulation by type I interferon drives neuropathology and neurologic dysfunction following traumatic brain injury

Fig. 8

IFNAR deficiency reduces thalamic neuronal loss following TBI. Neuronal loss was quantified by IHC using NeuN (green) staining in WT and IFNAR KO subjects. Representative NeuN staining in the thalamus at 7 (A and B) and 31 days (D and E) following TBI or control. Scale bar = 100 μm. Quantification of NeuN+ cells in the thalamus (C and F). Error bars depict mean ± SEM. Statistical analysis by two-way ANOVA with Tukey’s test for multiple comparisons. *p < 0.05, n = 4–8 control mice/group, n = 6–10 TBI mice/group

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